California Certified Pharmacy
Technician Advanced (Cpht-Adv) Exam
Questions And Correct Answers
(Verified Answers) Plus Rationales 2025
Q&A | Instant Download Pdf
1. What is the primary purpose of the USP Chapter <800>?
A. To establish billing guidelines for hazardous drugs
B. To protect healthcare personnel from hazardous drug exposure
C. To define reimbursement policies for specialty medications
D. To regulate controlled substance storage
USP <800> sets standards to minimize exposure to hazardous drugs for
healthcare workers and patients.
2. Which of the following is a Schedule II controlled substance?
A. Diazepam
B. Tramadol
C. Oxycodone
D. Pregabalin
Oxycodone is a Schedule II drug due to its high potential for abuse and
dependence.
,3. What is the maximum allowable beyond-use date for a non-sterile
compounded oral suspension with water as a solvent?
A. 14 days refrigerated
B. 14 days refrigerated or frozen
C. 30 days at room temperature
D. 7 days refrigerated
USP <795> states that water-containing oral formulations should not
exceed 14 days refrigerated.
4. Which enzyme is primarily responsible for drug metabolism in the liver?
A. MAO
B. CYP450
C. COMT
D. GGT
Cytochrome P450 (CYP450) enzymes are the primary enzymes in hepatic
drug metabolism.
5. Which federal law created the requirement for child-resistant
packaging?
A. Durham-Humphrey Amendment
B. Food, Drug, and Cosmetic Act
C. Poison Prevention Packaging Act
D. Orphan Drug Act
The Poison Prevention Packaging Act of 1970 mandates child-resistant
packaging for many medications.
6. Which of the following insulin types is long-acting?
A. Insulin lispro
B. Insulin regular
C. Insulin glargine
D. Insulin NPH
, Insulin glargine (e.g., Lantus) is a long-acting insulin used for basal glucose
control.
7. What is the correct technique for reconstituting a lyophilized powder in
a vial?
A. Add solvent quickly and shake the vial
B. Add solvent slowly and gently swirl
C. Add solvent slowly and vigorously shake
D. Add solvent quickly and roll the vial
To preserve drug stability, add diluent slowly and gently swirl to dissolve
the powder.
8. What is the role of the laminar airflow workbench in sterile
compounding?
A. Temperature control
B. Drug identification
C. Provide a contaminant-free environment
D. Label verification
Laminar airflow workbenches filter air to protect sterile products from
contamination.
9. Which of the following antibiotics should NOT be taken with calcium-
containing foods?
A. Ciprofloxacin
B. Amoxicillin
C. Cephalexin
D. Azithromycin
Ciprofloxacin interacts with calcium, reducing its absorption and
effectiveness.
10. What type of IV solution is D5NS?
A. Hypotonic
B. Isotonic
Technician Advanced (Cpht-Adv) Exam
Questions And Correct Answers
(Verified Answers) Plus Rationales 2025
Q&A | Instant Download Pdf
1. What is the primary purpose of the USP Chapter <800>?
A. To establish billing guidelines for hazardous drugs
B. To protect healthcare personnel from hazardous drug exposure
C. To define reimbursement policies for specialty medications
D. To regulate controlled substance storage
USP <800> sets standards to minimize exposure to hazardous drugs for
healthcare workers and patients.
2. Which of the following is a Schedule II controlled substance?
A. Diazepam
B. Tramadol
C. Oxycodone
D. Pregabalin
Oxycodone is a Schedule II drug due to its high potential for abuse and
dependence.
,3. What is the maximum allowable beyond-use date for a non-sterile
compounded oral suspension with water as a solvent?
A. 14 days refrigerated
B. 14 days refrigerated or frozen
C. 30 days at room temperature
D. 7 days refrigerated
USP <795> states that water-containing oral formulations should not
exceed 14 days refrigerated.
4. Which enzyme is primarily responsible for drug metabolism in the liver?
A. MAO
B. CYP450
C. COMT
D. GGT
Cytochrome P450 (CYP450) enzymes are the primary enzymes in hepatic
drug metabolism.
5. Which federal law created the requirement for child-resistant
packaging?
A. Durham-Humphrey Amendment
B. Food, Drug, and Cosmetic Act
C. Poison Prevention Packaging Act
D. Orphan Drug Act
The Poison Prevention Packaging Act of 1970 mandates child-resistant
packaging for many medications.
6. Which of the following insulin types is long-acting?
A. Insulin lispro
B. Insulin regular
C. Insulin glargine
D. Insulin NPH
, Insulin glargine (e.g., Lantus) is a long-acting insulin used for basal glucose
control.
7. What is the correct technique for reconstituting a lyophilized powder in
a vial?
A. Add solvent quickly and shake the vial
B. Add solvent slowly and gently swirl
C. Add solvent slowly and vigorously shake
D. Add solvent quickly and roll the vial
To preserve drug stability, add diluent slowly and gently swirl to dissolve
the powder.
8. What is the role of the laminar airflow workbench in sterile
compounding?
A. Temperature control
B. Drug identification
C. Provide a contaminant-free environment
D. Label verification
Laminar airflow workbenches filter air to protect sterile products from
contamination.
9. Which of the following antibiotics should NOT be taken with calcium-
containing foods?
A. Ciprofloxacin
B. Amoxicillin
C. Cephalexin
D. Azithromycin
Ciprofloxacin interacts with calcium, reducing its absorption and
effectiveness.
10. What type of IV solution is D5NS?
A. Hypotonic
B. Isotonic
