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PCB 4233 EXAM 3 QUESTIONS WITH COMPLETE ANSWERS

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PCB 4233 EXAM 3 QUESTIONS WITH COMPLETE ANSWERS

Institution
PCB 4233
Course
PCB 4233

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Allergic responses to inhaled antigens occur when an individual is first sensitized to
the antigen (i.e., the allergen), inducing an immune response, and then has a
subsequent exposure to the same antigen. The sensitization phase is characterized by:


A. Recruitment of large numbers of neutrophils to the site of allergen entry
B. Induction of a CD4 T cell type II immune response
C. Activation of tissue-resident ILC3 cells following stimulation by the allergen
D. Induction of IgA antibodies against the allergen
E. Production of high concentrations of IL-12 and IL-23 by tissue-resident dendritic
cells


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B. Induction of a CD4 T cell type II immune response




A common misconception is that our immune system fails to make a productive
immune response to HIV infection, thereby leading to chronic infection. In fact,

,following a primary HIV infection, our immune system:


A. Generates immunity at the mucosal surfaces, but does not control the systemic
infection
B. Generates a response characterized by a cytokine storm that is poor at controlling
virus replication
C. Generates an inappropriate Type II instead of a Type I response
D. Generates a response that efficiently controls viral replication
E. Generates a T cell but not humoral immunity to the virus


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D. Generates a response that efficiently controls viral replication




Anaphylaxis can be triggered by cross-linking of IgE receptors on:


A. B cells
B. Mast cells
C. T cells
D. Dendritic Cells
E. Macrophages


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B. Mast cells




In type III immune response, both TH17 and ILC3 cells secrete IL-17 to activate:


A.Macrophages
B.Dendritic cells
C.Neutrophils
D.B cells
E.Eosinophils

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C. Neutrophils




The injection of tuberculin into the skin of a sensitized individual elicits:


A. Mantoux reaction
B. Serum sickness
C. Celiac disease
D. Arthus reaction
E. Netherton's syndrome


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A. Mantoux reaction




Which description of autoimmune diseases is NOT true?


A. In Type I diabetes patients, pancreatic cells are coated by IgG and consequently
removed by phagocytosis.
B. Autoimmunity is often the result of hypoactive Treg cells.
C. In Grave's disease, the body produces autoantibodies against the thyroid-
stimulating hormone (TSH) receptor.
D. Nucleosome subunits of chromatin are autoantigens in systemic lupus
erythematosus (SLE).
E. Sometimes autoimmunity is induced by infection through a mechanism called
"molecular mimicry".


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Institution
PCB 4233
Course
PCB 4233

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