Using what you know about positive and negative selection, which of the following is
false?
a.) Double positive thymocytes are the most abundant subpopulation in the thymus
b.) Mature T cells will recognize foreign MHC/peptide combinations
c.) Negative selection results in self-tolerance
d.) The majority of double positive thymocytes never meet selection criteria and die
by apoptosis in the thymus
e.) All of the above are correct
Give this one a try later!
Answer: b; Mature T cells recognize only foreign antigen combined with
self-MHC molecules
,MHC restriction of (AB) T cells and (YG) T cells?
Give this one a try later!
(AB) T cells:
CD4: MHC class 2 restricted
CD8: MCH class 1 restricted
(YG) T cells:
Not MHC restricted
What is the primary immune response which is responsible for dealing with helminths?
a) Tc cell-mediated
b) TH2 cell-mediated
c) Plasma cell-mediated
d) Humoral (antibody)
e) Complement
Give this one a try later!
Answer: b) TH2 cell-mediated
\alpha\betaαβ T cells differ from \gamma\deltaγδ T cells in all of the following ways
except:
A) \gamma\deltaγδ T cells utilize a small TCR V gene germ-line repertoire, while
,\alpha\betaαβ T cells have access to a large repertoire.
B) \gamma\deltaγδ T cells make up only a small portion of the total T cell population.
C) Unlike the more well-known \alpha\betaαβ T cell surface markers, \gamma\deltaγδ
T cells generally express the surface markers CD4+CD8+ and CD4-CD8-.
D) The \gamma\deltaγδ T cells MHC restrictions are the exact opposite to
\alpha\betaαβ T cell MHC restrictions.
E) More than one of the above statements is correct.
Give this one a try later!
Answer: E (neither C nor D describe the correct differences between the 2
types of T cells)
Why should babies drink the liquid-y runny breast milk that is cloudy and not white?
What is it called?
Give this one a try later!
Colostrum.
Breasts produce colostrum and is normally yellow or orange. It also tends
to be sticky and low in fat, high in carbs and most importantly, antibodies.
Colostrum contains immune cells and many antibodies such as IgA, IgM
and Ig M
What is the TCR V gene germ-line repertoir for (AB) and (YG) T cells?
Give this one a try later!
, (AB) T cells: large
(YG) T cells: small
Apoptosomes are initiated to induce apoptosis. In regard to the complex, what
biological substrates are required to create the apoptosome?
A: CD3, CCR7, Caspase-8
B: Cytochrome C, Pro-Caspase 9, Apaf-1
C: Cytochrome C, Caspase 9, Apaf-1
D: Bim, Cytochrome C, Caspase 3
Give this one a try later!
Answer: C. Caspase 9 is activate, and is within this form, as it becomes part
of the apoptosome complex.
Where is the IgA plasma-producing cell found within the GI system?
A. Mucosal Epithelium
B. Lamina Propria
C. Lumen
Give this one a try later!
Answer: B. Lamina Propria
false?
a.) Double positive thymocytes are the most abundant subpopulation in the thymus
b.) Mature T cells will recognize foreign MHC/peptide combinations
c.) Negative selection results in self-tolerance
d.) The majority of double positive thymocytes never meet selection criteria and die
by apoptosis in the thymus
e.) All of the above are correct
Give this one a try later!
Answer: b; Mature T cells recognize only foreign antigen combined with
self-MHC molecules
,MHC restriction of (AB) T cells and (YG) T cells?
Give this one a try later!
(AB) T cells:
CD4: MHC class 2 restricted
CD8: MCH class 1 restricted
(YG) T cells:
Not MHC restricted
What is the primary immune response which is responsible for dealing with helminths?
a) Tc cell-mediated
b) TH2 cell-mediated
c) Plasma cell-mediated
d) Humoral (antibody)
e) Complement
Give this one a try later!
Answer: b) TH2 cell-mediated
\alpha\betaαβ T cells differ from \gamma\deltaγδ T cells in all of the following ways
except:
A) \gamma\deltaγδ T cells utilize a small TCR V gene germ-line repertoire, while
,\alpha\betaαβ T cells have access to a large repertoire.
B) \gamma\deltaγδ T cells make up only a small portion of the total T cell population.
C) Unlike the more well-known \alpha\betaαβ T cell surface markers, \gamma\deltaγδ
T cells generally express the surface markers CD4+CD8+ and CD4-CD8-.
D) The \gamma\deltaγδ T cells MHC restrictions are the exact opposite to
\alpha\betaαβ T cell MHC restrictions.
E) More than one of the above statements is correct.
Give this one a try later!
Answer: E (neither C nor D describe the correct differences between the 2
types of T cells)
Why should babies drink the liquid-y runny breast milk that is cloudy and not white?
What is it called?
Give this one a try later!
Colostrum.
Breasts produce colostrum and is normally yellow or orange. It also tends
to be sticky and low in fat, high in carbs and most importantly, antibodies.
Colostrum contains immune cells and many antibodies such as IgA, IgM
and Ig M
What is the TCR V gene germ-line repertoir for (AB) and (YG) T cells?
Give this one a try later!
, (AB) T cells: large
(YG) T cells: small
Apoptosomes are initiated to induce apoptosis. In regard to the complex, what
biological substrates are required to create the apoptosome?
A: CD3, CCR7, Caspase-8
B: Cytochrome C, Pro-Caspase 9, Apaf-1
C: Cytochrome C, Caspase 9, Apaf-1
D: Bim, Cytochrome C, Caspase 3
Give this one a try later!
Answer: C. Caspase 9 is activate, and is within this form, as it becomes part
of the apoptosome complex.
Where is the IgA plasma-producing cell found within the GI system?
A. Mucosal Epithelium
B. Lamina Propria
C. Lumen
Give this one a try later!
Answer: B. Lamina Propria
