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PCB 4233 IMMUNOLOGY EXAM 1 QUESTIONS WITH COMPLETE ANSWERS

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PCB 4233 IMMUNOLOGY EXAM 1 QUESTIONS WITH COMPLETE ANSWERS

Institution
PCB 4233
Course
PCB 4233

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Bcl-2


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transcription factor that inhibits apoptosis
-decreased levels in activated lymphocytes (homeostasis)




MMR vaccine


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protects against measles, mumps, and rubella; should be given to children
12-15 m/o and again between age 4-6 or 11-12 if not former

,pattern recognition receptors


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receptors that recognize PAMPs; some trigger phagocytosis or activate
another resopnse




syngeneic stem cell transplant


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transfer of stem cells from identical twins tissue




B cell receptor (BCR)


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Molecule on the surface of a B cell that binds to a specific antigen;
essentially an antibody with transmembrane domain
-ability to recognize molecules other than proteins (unlike T cells)




herd immunity


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, works by decreasing the number of individuals who can harbor and spread
an infectious agent; significantly decreasing the chances that susceptible
individuals will become infected




CD4


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-present on T helper cells
-adhesion molecule that binds to MHC II
-involved in signal transduction




pluripotent stem cells


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Stem cells that can become almost all types of tissues and cells in the
body.
-embryonic stem cells
-HSCs




mumps


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, contagious viral disease that leads to painful swelling of the salivary glands
-most common in age 2-12 if not vaccinated
-12-24 day incubation period




kidney macrophages


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mesangial cells




necrosis


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unplanned cell death -- cells swell up and burst; signifies danger/problems
-chromatic clumping
-swollen organelles
-flocculent mitochondria
-leads to inflammation




monocytes


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highly phagocytic mononuclear leukocytes; circulate for ~8 hours and then
mature into macrophages

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PCB 4233

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