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PCB 4233 IMMUNOLOGY EXAM 2 MATERIALQUESTIONS WITH COMPLETE ANSWERS

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PCB 4233 IMMUNOLOGY EXAM 2 MATERIALQUESTIONS WITH COMPLETE ANSWERS

Institution
PCB 4233
Course
PCB 4233

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Synthesized de novo, released by all effector T cells


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Cytokines




IFN-γ, activate macrophages to kill intravesicular bacteria


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TH1 cells




neonatal Fc receptor

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FcRn




during presentation, many TCRs are bound to MHC-peptide complexes, possible
micro clustering


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Aggregation




The process of destroying B and T cells that react to self antigens


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clonal deletion




antigen: antibody complex, bind Fc receptors and/or complement receptors


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Immune complex




highly expressed during heavy and light chain rearrangement, briefly reduced in
between

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RAG1/2




Macrophages can be activated by


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antigens from intravesicular pathogens




phosphorylates LAT and SLP76


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ZAP70




-Morphology change
-No more phagocytosis
-MHC class II (green) are reaching the cell surface


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DCs in lymphatic circulation




bone marrow and thymus

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central lymphoid organs




ITIM recruits phosphatase, binds to B7 ligand family PD-L1/2


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PD-1




high expression during heavy chain rearrangement


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TdT




CAM that allows white blood cells to "anchor" at damage sites


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selectin




SH2 domain-containing leukocyte protein of 76 kDa; cytoskeleton rearrangement


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PCB 4233

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