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attacks, NTG
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1 Combining bile acid-binding resins with ___________ or________ can lower LDL by 40% to 50%
beta-blockers are used in the tx of angina as they have been shown to reduce the number of anginal
2
___________; and reduce_____ use
the action of this drug class works by inhibiting the enzyme responsible for converting HMG-CoA to
3
mevalonate, ultimately reducing liver cholesterol
_______________ is a potent vasodilator that acts directly on the________ muscle of blood vessels. It
4
produces both ________________ and__________ vasodilation, thus reducing both preload and afterload on
the heart
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Terms in this set (182)
Combining bile acid-binding niacin, statin
resins with ___________ or ___________
can lower LDL by 40% to 50%
cholestyramine bile-acid binding resin
colestipol bile-acid binding resin
colesevelam bile-acid binding resin
The action of this class of drugs bile-acid binding resins
works by binding to bile acids,
promoting an increased
metabolism of cholesterol
, common adverse effects of bile- constipation, bloating, fullness, nausea, flatulence
acid binding resins include GI sx
such as:
- (hint: lack of BM)
- (hint: air in stomach)
or a feeling of _______________
- (hint: pre puke)
- _____________ (farting)
serious adverse effect of bile- K
acid binding resins is vitamin
_______ deficiency, but this is rare
________________ to niacin (nicotinic tolerance
acid) develops quickly
niacin (nicotinic acid) is used to hyperlipidemias
treat _________________
the patient taking niacin orthostatic hypotension
(nicotinic acid) should be on
______________ ______________
precautions
symptoms of adverse effects aspirin, ibuprofen, food
from niacin can be reduced by
taking ___________ or _________ 30
minutes before each dose, or by
taking it with ____________
HMG-CoA Reductase Inhibitors statins
the action of this drug class statins (HMG-CoA reductase inhibitors)
works by inhibiting the enzyme
responsible for converting
HMG-CoA to mevalonate,
ultimately reducing liver
cholesterol
Serious adverse effects of liver, myopathy, rhabdomyolysis, myoglobinuria
statins (HMG-CoA reductase
inhibitors) include:
- __________ (hepatic) dysfunction
-(hint: muscle tissue)
- ________________ (breakdown of
muscle tissue)
- _________________ (excess
myoglobin in the urine, can lead
to AKI)
early signs of myopathy: muscle aches, soreness, weakness
___________,__________ , and
______________
pinkish or red-tinged urine may rhabdomyolysis
be a sign of____________ in the
patient using statin therapy for
hyperlipidemia
rhabdomyolysis causes damage kidneys, myopathy
to the__________ and is a result
of progressing ______________