Clinical Medicine III (Clin Med III) – Arthropathies Q&A (60+ Questions) | 2025 | RA vs OA, Gout, CPPD, PsA, Sjogren's

This document contains over 60 expertly structured practice questions and answers from the Clinical Medicine III (Clin Med III) course, focusing on the comparative features and clinical presentations of various arthropathies. It provides a detailed breakdown of rheumatoid arthritis (RA) vs. osteoarthritis (OA), gout vs. pseudogout (CPPD), and distinctions among psoriatic arthritis (PsA), Sjogren's syndrome, Felty’s syndrome, and septic arthritis. Key topics include hallmark signs like Heberden’s and Bouchard’s nodes, pencil-in-cup deformity, dactylitis (sausage digits), and classic radiological findings such as rat bite lesions and chondrocalcinosis. The document also explains diagnostic markers (e.g., CRP, HLA-B27, HLA-DR4), synovial fluid analysis, and treatment options for acute and chronic gout (colchicine, probenecid). Ideal for medical students, nursing students, physician associate/assistant programs, and other health science learners reviewing rheumatologic conditions, musculoskeletal pathology, or preparing for clinical exams and OSCEs. Keywords: rheumatoid arthritis, osteoarthritis, gout, pseudogout, CPPD, psoriatic arthritis, Sjogren's syndrome, Felty’s syndrome, dactylitis, synovitis, colchicine, probenecid, rat bite lesions, Heberden’s nodes, Bouchard’s nodes, chondrocalcinosis, arthropathy comparison