BIOL 351/ BIOL351 Module 3: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
The neural tube forms from the folding of the neural plate. Which region of the neural tube is the
first to close?
B
The brain is derived from which of the following:
ectoderm
The nervous system begins as a flat neural plate that runs along the midline from rostral to
caudal. Folding is initiated with the [ Select ] anchored to the [ Select ] and changes shape while
the epidermal cells move toward the dorsal midline.
medial hingepoint cells
notochord
Crosstalk between the and ectoderm establish patterning that forms the neural tube.
mesoderm
Which of the following defects is a severe open neural tube defect caused by failure of rostral
neural tube closure?
anencephaly
, BIOL 351/ BIOL351 Module 3: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
The neural tube forms from the folding of the neural plate. Which region of the neural plate fuses
together to form the dorsal neural tube?
C
Which of the following is an occult, and not an open, neural tube defect?
Spina bifida occulta
Folate promotes neural tube closure. On a cellular basis, it is necessary for
.
nucleotide biosynthesis
The neural tube is regionalized by developmental gene regulation. Which of the following
correctly matches the gene and specified region?
Shh - ventralizing the neural tube
Which of the following regulates the segmentation of the hindbrain rhombomeres?
Hox gene expression
Which of these central nervous system structures are correctly listed in a rostral to caudal order?
, BIOL 351/ BIOL351 Module 3: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
Cerebrum, Pons, Spinal Cord
Which of the following represent antagonistic cues used in patterning the rostral/caudal axis if
the neural tube:
RA/FGF8
In the diagram of neural tube folding, indicate the region of tissue that will eventually form the
neural crest.
C
The process the neural crest cells use to delaminate from the dorsal neural tube is .
EMT, epithelial mesenchymal transition
Neural crest cells derive from the [ Select ] layer and give rise to the [ Select ].
ectoderm
peripheral nervous system
Neural crest cells can differentiate into multiple cells types. The following statement is TRUE or
FALSE: A unique feature of neural crest cells is that they have intrinsic programs that
predetermine their fate prior to delamination from the neural tube; Neural crest cells are not
influenced by extrinsic cues to instruct the outcome of the ultimate cell fate.
, BIOL 351/ BIOL351 Module 3: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
False
In developing radial glia, and are necessary to maintain the
progenitor state. Pick the best answer to fill in the blank below
Notch, Par3
In the diagram above, use the letters to indicate where proliferative neuroepithelial progenitors
are located?
D
Mitosis in neural epithelial progenitors occurs at the ventricular surface. A allows
one cell to differentiate while the other cell maintains as a NEP.
asymmetric division
Radial glia give rise to neurons and glia. Radial glia also direct cell migration because they
.
anchor to the ventricular and pial surface to provide structural support
Neurons in the central nervous system are nourished by , and myelinated by .
astrocytes, oligodendrocytes
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
The neural tube forms from the folding of the neural plate. Which region of the neural tube is the
first to close?
B
The brain is derived from which of the following:
ectoderm
The nervous system begins as a flat neural plate that runs along the midline from rostral to
caudal. Folding is initiated with the [ Select ] anchored to the [ Select ] and changes shape while
the epidermal cells move toward the dorsal midline.
medial hingepoint cells
notochord
Crosstalk between the and ectoderm establish patterning that forms the neural tube.
mesoderm
Which of the following defects is a severe open neural tube defect caused by failure of rostral
neural tube closure?
anencephaly
, BIOL 351/ BIOL351 Module 3: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
The neural tube forms from the folding of the neural plate. Which region of the neural plate fuses
together to form the dorsal neural tube?
C
Which of the following is an occult, and not an open, neural tube defect?
Spina bifida occulta
Folate promotes neural tube closure. On a cellular basis, it is necessary for
.
nucleotide biosynthesis
The neural tube is regionalized by developmental gene regulation. Which of the following
correctly matches the gene and specified region?
Shh - ventralizing the neural tube
Which of the following regulates the segmentation of the hindbrain rhombomeres?
Hox gene expression
Which of these central nervous system structures are correctly listed in a rostral to caudal order?
, BIOL 351/ BIOL351 Module 3: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
Cerebrum, Pons, Spinal Cord
Which of the following represent antagonistic cues used in patterning the rostral/caudal axis if
the neural tube:
RA/FGF8
In the diagram of neural tube folding, indicate the region of tissue that will eventually form the
neural crest.
C
The process the neural crest cells use to delaminate from the dorsal neural tube is .
EMT, epithelial mesenchymal transition
Neural crest cells derive from the [ Select ] layer and give rise to the [ Select ].
ectoderm
peripheral nervous system
Neural crest cells can differentiate into multiple cells types. The following statement is TRUE or
FALSE: A unique feature of neural crest cells is that they have intrinsic programs that
predetermine their fate prior to delamination from the neural tube; Neural crest cells are not
influenced by extrinsic cues to instruct the outcome of the ultimate cell fate.
, BIOL 351/ BIOL351 Module 3: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
False
In developing radial glia, and are necessary to maintain the
progenitor state. Pick the best answer to fill in the blank below
Notch, Par3
In the diagram above, use the letters to indicate where proliferative neuroepithelial progenitors
are located?
D
Mitosis in neural epithelial progenitors occurs at the ventricular surface. A allows
one cell to differentiate while the other cell maintains as a NEP.
asymmetric division
Radial glia give rise to neurons and glia. Radial glia also direct cell migration because they
.
anchor to the ventricular and pial surface to provide structural support
Neurons in the central nervous system are nourished by , and myelinated by .
astrocytes, oligodendrocytes
