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Nurs 611 Exam 3 Advanced Pathophysiology (Maryville University) Newest 2025 Complete 200 Questions And Correct Answers |Already Graded A

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Nurs 611 Exam 3 Advanced Pathophysiology (Maryville University) Newest 2025 Complete 200
Questions And Correct Answers |Already Graded A+



What is the most common cause of insufficient erythropoiesis in children?

a.

Folic acid deficiency

c.

Hemoglobin abnormality

b.

Iron deficiency

d.

Erythrocyte abnormality - ANSWER-B

Similar to the anemias of adulthood, ineffective erythropoiesis or premature destruction of erythrocytes
causes the anemias of childhood. The most common cause of insufficient erythropoiesis is iron
deficiency. The other options may be causes but are not common ones.



How does hemolytic disease of the newborn (HDN) cause acquired congenital hemolytic anemia?

a.

HDN develops when hypoxia or dehydration causes the erythrocytes to change shapes, which are then
recognized as foreign and removed from circulation.

b.

HDN is an alloimmune disease in which the mother's immune system produces antibodies against fetal
erythrocytes, which are recognized as foreign and removed from circulation.

c.

HDN develops when the polycythemia present in fetal life continues after birth, causing the excessive
number of erythrocytes to be removed from circulation.

d.

HDN is an autoimmune disease in which the fetus's immune system produces antibodies against fetal
erythrocytes, which are recognized as foreign and removed from circulation. - ANSWER-B

HDN is an alloimmune disease in which maternal blood and fetal blood are antigenically incompatible,
causing the mother's immune system to produce antibodies against fetal erythrocytes. Fetal
erythrocytes that have been attacked by (or bound to) maternal antibodies are recognized as foreign or

,defective by the fetal mononuclear phagocyte system and are removed from the circulation by
phagocytosis, usually in the fetal spleen. This selection is the only option that accurately explains how
HDN causes acquired congenital hemolytic anemia.



Erythroblastosis fetalis is defined as an:

a.

Allergic disease in which maternal blood and fetal blood are antigenically incompatible

b.

Alloimmune disease in which maternal blood and fetal blood are antigenically incompatible

c.

Autoimmune disease in immature nucleated cells that are released into the bloodstream

d.

Autosomal dominant hereditary disease - ANSWER-B

Erythroblastosis fetalis, also known as hemolytic disease of the newborn (HDN), is an alloimmune
disease in which maternal blood and fetal blood are antigenically incompatible, causing the mother's
immune system to produce antibodies against fetal erythrocytes. This selection is the only option that
accurately defines erythroblastosis fetalis.



In infant's hemoglobin must fall below ___ g/dl before signs of pallor, tachycardia, and systolic murmurs
occur.

a.

11

c.

7

b.

9

d.

5 - ANSWER-D

When the hemoglobin falls below 5 g/dl, pallor, tachycardia, and systolic murmurs may occur.



Which vitamin improves the absorption of oral iron taken to treat iron deficiency anemia in children?

,a.

A

c.

C

b.

B

d.

E - ANSWER-Of the available options, only additional vitamin C may be used to promote iron absorption.



Hemolytic disease of the newborn (HDN) can occur if the mother:

a.

Is Rh-positive and the fetus is Rh-negative

b.

Is Rh-negative and the fetus is Rh-positive

c.

Has type A blood and the fetus has type O

d.

Has type AB blood and the fetus has type B - ANSWER-B

HDN can occur only if antigens on fetal erythrocytes differ from antigens on maternal erythrocytes.
Maternal-fetal incompatibility exists only if the mother and fetus differ in ABO blood type or if the fetus
is Rh-positive and the mother is Rh-negative. This erythrocyte incompatibility does not exist in any of the
other options.



When diagnosed with hemolytic disease of the newborn (HDN), why does the newborn develop
hyperbilirubinemia after birth but not in utero?

a.

Excretion of unconjugated bilirubin through the placenta into the mother's circulation is no longer
possible.

b.

Hemoglobin does not break down into bilirubin in the intrauterine environment.

, c.

The liver of the fetus is too immature to conjugate bilirubin from a lipid-soluble to water-soluble form.

d.

The destruction of erythrocytes producing bilirubin is greater after birth. - ANSWER-A

Hyperbilirubinemia occurs in the neonate after birth because excretion of lipid-soluble unconjugated
bilirubin through the placenta is no longer possible. This selection is the only option that accurately
explains why HDN causes hyperbilirubinemia after birth but not in utero.



Fetuses who do not survive anemia in utero are usually stillborn with gross edema of the entire body.
Which term is used to identify this condition?

a.

Spherocytosis

c.

Erythroblastosis fetalis

b.

Icterus gravis neonatorum

d.

Hydrops fetalis - ANSWER-D

Fetuses that do not survive anemia in utero are usually stillborn with gross edema in the entire body, a
condition called hydrops fetalis. This selection is the only option that accurately identifies the condition
with these specific symptoms.



What is the name of the disorder in which levels of bilirubin remain excessively high in the newborn and
are deposited in the brain?

a.

Kernicterus

c.

Jaundice

b.

Icterus neonatorum

d.

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