limb bud
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early stage of the arm
The haltere is a
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balancer organ on flies
Case Study: Chick Embryo -> "how babies get made"
What is the experiment, result, interpretation/conclusion, and comments?
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experiment: transplant thigh tissue to the tip of the wing
results: the transplanted cells make a toe
conclusion: the leg and wing use the same coordinate system
comments: a single "universe" gradient is used in all organisms
interpretation mode
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same coordinate system, different interpretations
totipotent cells
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can differentiate into any cell type
,Pattern = set of all ___,___
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Positions, state
state meaning color, kidney, skin, etc
fate mapping
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general territorial diagrams of embryonic development
Case Study: Frog Retina & Tectum Experiment: Half of retina becomes radioactive &
pours those cells on tectum
What are the results, interpretation/conclusion, and comments?
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results: cells stuck to the "correct" half of the tectum
conclusion: validates Sperry's neurospecificity hypothesis
comments: radioactivity lets you test whether specificity to positional is
involved
Recording definition
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measuring the concentration of a morphogen and sourcing that
information as a positional value which then involves turning genes "on" or
"off."
Homeotic mutations in Drosophila
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transforms haltere into new wings
Recombination
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crossing over between homologous chromosomes
The sea shell case takeaway
What is the experiment, result, interpretation/conclusion, and comments?
Give this one a try later!
Give this one a try later!
early stage of the arm
The haltere is a
,Give this one a try later!
balancer organ on flies
Case Study: Chick Embryo -> "how babies get made"
What is the experiment, result, interpretation/conclusion, and comments?
Give this one a try later!
experiment: transplant thigh tissue to the tip of the wing
results: the transplanted cells make a toe
conclusion: the leg and wing use the same coordinate system
comments: a single "universe" gradient is used in all organisms
interpretation mode
Give this one a try later!
same coordinate system, different interpretations
totipotent cells
Give this one a try later!
can differentiate into any cell type
,Pattern = set of all ___,___
Give this one a try later!
Positions, state
state meaning color, kidney, skin, etc
fate mapping
Give this one a try later!
general territorial diagrams of embryonic development
Case Study: Frog Retina & Tectum Experiment: Half of retina becomes radioactive &
pours those cells on tectum
What are the results, interpretation/conclusion, and comments?
Give this one a try later!
results: cells stuck to the "correct" half of the tectum
conclusion: validates Sperry's neurospecificity hypothesis
comments: radioactivity lets you test whether specificity to positional is
involved
Recording definition
, Give this one a try later!
measuring the concentration of a morphogen and sourcing that
information as a positional value which then involves turning genes "on" or
"off."
Homeotic mutations in Drosophila
Give this one a try later!
transforms haltere into new wings
Recombination
Give this one a try later!
crossing over between homologous chromosomes
The sea shell case takeaway
What is the experiment, result, interpretation/conclusion, and comments?
Give this one a try later!
