After isolating the rough endoplasmic reticulum from the rest of the cytoplasm, you
purify the RNAs attached to it. Which of the following proteins do you expect the
RNA from the rough endoplasmic reticulum to encode?
a. nucleus proteins
b. ER lumen proteins
c. plasma membrane proteins
d. b and c
Give this one a try later!
ER lumen proteins and plasma membrane proteins
The figure below shows the organization of a protein that resides in the ER membrane.
The N- and C-termini of the protein are labeled. Boxes 1, 2, and 3 represent
membrane-spanning sequences. Box 1 is an internal start-transfer signal. This protein
does not have an N-terminal signal sequence. W, X, Y and Z are non-membrane-
spanning regions of the protein. (SEE PICTURE #40)
,Once this protein is fully translocated, where will region X be?
a. In the cytoplasm
b. In the ER lumen
c. Inserted into the ER membrane
d. Degraded by signal peptidase
Give this one a try later!
In the ER lumen
Which of the following is triggered by the Unfolded Protein Response (UPR)?
a. Inhibition of chaperone genes
b. Increase in protein synthesis
c. Activation of genes that increase the protein-folding capacity of the ER
d. All of the above
Give this one a try later!
Activation of genes that increase the protein-folding capacity of the ER
Experiments performed by Hans Krebs in the 1930s revealed that the set of reactions
that oxidize food molecules and produce CO2 occurs in a cycle. In one experiment,
Krebs exposed pigeon muscles to malonate, a compound that inhibits succinate
dehydrogenase—the enzyme that converts succinate to fumarate (see figure below).
CITRATE-->-->-->succinate--> fumerate-->--> oxaloacetate
Which of the following observations, made in malonate-treated muscle, led Krebs to
believe that this set of reactions is cyclical?
a. If citrate were added, succinate would accumulate.
b. If succinate were added, fumarate would accumulate.
c. If oxaloacetate were added, succinate would accumulate.
d. Regardless of what he added, large amounts of oxygen would be consumed.
Give this one a try later!
, If oxaloacetate were added, succinate would accumulate.
The proton concentration gradient and the membrane potential across the inner
mitochondrial membrane tend to work __________ in driving __________ through ATP
synthase.
a. together; electrons
b. against one another; protons
c. together; protons
d. against one another; electrons
Give this one a try later!
together; protons
Glycolysis generates more stored energy than it expends. __________ are invested in the
first phase of glycolysis to generate __________, __________, and 2 pyruvates in the third
phase of glycolysis.
a. 2 ATP; 4 NADH; 2 ATP
b. 4 ATP; 4 NADH; 4 ATP
c. 2 ATP; 2 NADH; 4 ATP
d. 4 ATP; 2 NADH; 2 ATP
e. 2 ATP; 2 NADH; 2 ATP
Give this one a try later!
2 ATP; 2 NADH; 4 ATP
Endosomes are "sorting stations" for endocytosed materials.
a. True
purify the RNAs attached to it. Which of the following proteins do you expect the
RNA from the rough endoplasmic reticulum to encode?
a. nucleus proteins
b. ER lumen proteins
c. plasma membrane proteins
d. b and c
Give this one a try later!
ER lumen proteins and plasma membrane proteins
The figure below shows the organization of a protein that resides in the ER membrane.
The N- and C-termini of the protein are labeled. Boxes 1, 2, and 3 represent
membrane-spanning sequences. Box 1 is an internal start-transfer signal. This protein
does not have an N-terminal signal sequence. W, X, Y and Z are non-membrane-
spanning regions of the protein. (SEE PICTURE #40)
,Once this protein is fully translocated, where will region X be?
a. In the cytoplasm
b. In the ER lumen
c. Inserted into the ER membrane
d. Degraded by signal peptidase
Give this one a try later!
In the ER lumen
Which of the following is triggered by the Unfolded Protein Response (UPR)?
a. Inhibition of chaperone genes
b. Increase in protein synthesis
c. Activation of genes that increase the protein-folding capacity of the ER
d. All of the above
Give this one a try later!
Activation of genes that increase the protein-folding capacity of the ER
Experiments performed by Hans Krebs in the 1930s revealed that the set of reactions
that oxidize food molecules and produce CO2 occurs in a cycle. In one experiment,
Krebs exposed pigeon muscles to malonate, a compound that inhibits succinate
dehydrogenase—the enzyme that converts succinate to fumarate (see figure below).
CITRATE-->-->-->succinate--> fumerate-->--> oxaloacetate
Which of the following observations, made in malonate-treated muscle, led Krebs to
believe that this set of reactions is cyclical?
a. If citrate were added, succinate would accumulate.
b. If succinate were added, fumarate would accumulate.
c. If oxaloacetate were added, succinate would accumulate.
d. Regardless of what he added, large amounts of oxygen would be consumed.
Give this one a try later!
, If oxaloacetate were added, succinate would accumulate.
The proton concentration gradient and the membrane potential across the inner
mitochondrial membrane tend to work __________ in driving __________ through ATP
synthase.
a. together; electrons
b. against one another; protons
c. together; protons
d. against one another; electrons
Give this one a try later!
together; protons
Glycolysis generates more stored energy than it expends. __________ are invested in the
first phase of glycolysis to generate __________, __________, and 2 pyruvates in the third
phase of glycolysis.
a. 2 ATP; 4 NADH; 2 ATP
b. 4 ATP; 4 NADH; 4 ATP
c. 2 ATP; 2 NADH; 4 ATP
d. 4 ATP; 2 NADH; 2 ATP
e. 2 ATP; 2 NADH; 2 ATP
Give this one a try later!
2 ATP; 2 NADH; 4 ATP
Endosomes are "sorting stations" for endocytosed materials.
a. True
