Where are intermediate filaments found?
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Throughout the cytoplasm
At cell junctions called desmosomes
Inside the nucleus
What is the organizing center for microtubules in cilium and flagellum?
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The basal body
Not the centrosome
,Does the plus end of a microtubule have beta-tubulins or alpha-tubulins exposed?
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Beta-tubulins
The end of with the beta-tubulin showing is the plus end
What is the general structure of an IF tetramer?
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It is made up of 2 dimers that form a staggered, antiparallel
conformation.
The tetramer is staggered because the dimers are not
completely lined up with each other
The tetramer is antiparallel because the C-terminal of one
dimer is facing the the N-terminal of another dimer.
What is the function of actin binding proteins?
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, They control the assemble and stability of actin filaments.
What do intermediate filaments do at desmosomes?
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They indirectly connect to the intermediate filaments of
surrounding cells to create a continuous mechanical link
from cell to cell.
This helps distribute local mechanical stress over multiple
cells of the same tissue.
Instead of one cell experiencing a lot of mechanical stress
and breaking, local tension can be spread out among a
group of surrounding cells.
Progeria is a rare class of premature aging disorders. Defects in nuclear lamins can
cause progeria. Mutated nuclear lamins cause the nuclei to loose their stability. What
affect does this have on the individual?
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, Nuclear lamins are directly connected to chromatin in the
nucleus. Loss of nuclear stability will affect gene expression,
chromosomal positioning, and cause defects in cell division.
An important characteristic of the cytoskeleton is its flexibility. How does this help the
cell carry out its functions?
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The flexibility of the cytoskeleton helps the cell change shape, move, and
divide.
Motor proteins can either bind to cargo directly or they can bind to vesicles via
adaptor proteins. What benefit do adaptor proteins provide to motor proteins?
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Adaptor proteins allow for kinesin and dyein to bind to
many different types of cargo.
Instead of having a binding site that only recognizes a
specific vesicle, kinesin and dynein proteins can have
binding sites that recognize a whole class of adaptor
proteins that all carry different types of cargo.
What kind of proteins form intermediate filaments?
Give this one a try later!
Throughout the cytoplasm
At cell junctions called desmosomes
Inside the nucleus
What is the organizing center for microtubules in cilium and flagellum?
Give this one a try later!
The basal body
Not the centrosome
,Does the plus end of a microtubule have beta-tubulins or alpha-tubulins exposed?
Give this one a try later!
Beta-tubulins
The end of with the beta-tubulin showing is the plus end
What is the general structure of an IF tetramer?
Give this one a try later!
It is made up of 2 dimers that form a staggered, antiparallel
conformation.
The tetramer is staggered because the dimers are not
completely lined up with each other
The tetramer is antiparallel because the C-terminal of one
dimer is facing the the N-terminal of another dimer.
What is the function of actin binding proteins?
Give this one a try later!
, They control the assemble and stability of actin filaments.
What do intermediate filaments do at desmosomes?
Give this one a try later!
They indirectly connect to the intermediate filaments of
surrounding cells to create a continuous mechanical link
from cell to cell.
This helps distribute local mechanical stress over multiple
cells of the same tissue.
Instead of one cell experiencing a lot of mechanical stress
and breaking, local tension can be spread out among a
group of surrounding cells.
Progeria is a rare class of premature aging disorders. Defects in nuclear lamins can
cause progeria. Mutated nuclear lamins cause the nuclei to loose their stability. What
affect does this have on the individual?
Give this one a try later!
, Nuclear lamins are directly connected to chromatin in the
nucleus. Loss of nuclear stability will affect gene expression,
chromosomal positioning, and cause defects in cell division.
An important characteristic of the cytoskeleton is its flexibility. How does this help the
cell carry out its functions?
Give this one a try later!
The flexibility of the cytoskeleton helps the cell change shape, move, and
divide.
Motor proteins can either bind to cargo directly or they can bind to vesicles via
adaptor proteins. What benefit do adaptor proteins provide to motor proteins?
Give this one a try later!
Adaptor proteins allow for kinesin and dyein to bind to
many different types of cargo.
Instead of having a binding site that only recognizes a
specific vesicle, kinesin and dynein proteins can have
binding sites that recognize a whole class of adaptor
proteins that all carry different types of cargo.
What kind of proteins form intermediate filaments?
