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NR 507 PATHOPHYSIOLOGY MIDTERM QUESTIONS WITH COMPLETE ANSWERS

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NR 507 PATHOPHYSIOLOGY MIDTERM QUESTIONS WITH COMPLETE ANSWERS

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NR 507
Course
NR 507

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Define polycythemia vera


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Overproduction of RBCs and splenomegaly




What does a reduced FEV1, FVC, and TLC show?

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A restrictive lung disorder




Mediators for Type 1 hypersensitivity reaction


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*Histamine: contracts bronchial smooth muscles, increases vascular
permeability, and causes vasodilation
*Bioactive lipid-derived mediators (i.e. leukotrienes, PAF, prostaglandins):
released slowly, cause recruitment of other inflammatory cells (neutrophils,
eosinophils) to promote vascular permeability and edema,
bronchoconstriction or rhinitis, induces further release of histamine




Define normochromic anemia


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RBCs have normal hgb, normal color
MCHC is normal (bt 32-36%)
Types: aplastic, post-hemorrhagic, and hemolytic




Define thrombocytopenia


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, platelet count less than 150K of blood; decreased platelet production,
increased consumption, or both




Define obstructive pulmonary disease


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Airway obstruction that worsens with expiration
More force or more time is required to expire air and emptying lungs is
slowed
*infiltration of the lung by inflammatory cells with the release of numerous
cytokines that contribute to airway damage and mucus production
*decreased FEV1 (<80%)
*FEV1/FVC <70%
*FVC <80%
*TLC >120%




Define right heart failure


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Inability of the right ventricle to provide adequate blood flow into the
pulmonary circulation
*results from severe LHF




Posthemorrhagic anemia


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, Normocytic-normochromic anemia: caused by acute blood loss
# of RBCs lost is greater than # of RBCs produced
MCV and MCHC are normal, high reticulocyte count




Define peripheral artery disease


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Atherosclerotic disease of arteries that perfuses the limbs, especially the
lower extremities




Define spirometry


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Measures exhaled flow rates and volumes such as TV, VC, and FEV1




Transfusion reaction


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a serious, and potentially fatal, complication of a blood transfusion in which
a severe immune response occurs because the patient's blood and the
donated blood do not match




Define transient myocardial ischemia

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