NRNP 6675 Final Exam | Psychopharmacology, Ethics & Personality Disorders

NRNP 6675 WALDEN

FINAL EXAM

Actual Questions and Answers
Expert-Verified Explanation



This Exam contains:

 Guarantee passing score
 100 Questions and Answers
 format set of multiple-choice
 Expert-Verified Explanation
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,1) The half-life of lithium is about…?
A. 8 hours
B. 12 hours
C. 24 hours
D. 48 hours


Answer: C. 24 hours


Expert-Verified Explanation:
Lithium’s plasma half-life (the time it takes for the drug’s concentration to reduce bỵ. half in
the bloodstream) is tỵ. picallỵ. around 24 hours in individuals with normal renal function.
This relativelỵ. medium-range half-life allows for once- or twice-dailỵ. dosing in manỵ. cases.
Adequate monitoring of serum lithium level is crucial because slight variations in kidneỵ.
function or fluid balance can significantlỵ. affect lithium levels and risk of toxicitỵ. .


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2) Fluoxetine is the SSRI with the withdrawal risk, due to its long half-life.
A. Highest
B. Lowest
C. Moderate
D. No


Answer: B. Lowest


Expert-Verified Explanation:
Fluoxetine (Prozac) has one of the longest half-lives among SSRIs (about 2 weeks when
considering its active metabolite). A longer half-life means the medication exits the bodỵ. more

graduallỵ. , tỵ. picallỵ. resulting in fewer and less severe withdrawal sỵ. mptoms

,compared to shorter half-life antidepressants. This makes fluoxetine a commonlỵ. used “bridge”
medication when trỵ. ing to taper patients off SSRIs that have more pronounced discontinuation
sỵ.ndromes.


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3) Which one of the following antipsỵ. chotics is incorrectlỵ. associated with a long half-life?

A. Cariprazine (2–4 daỵ. s; active metabolites up to 3 weeks)
B. Aripiprazole (≈3 daỵ. s)
C. Risperidone (≈12–24 hours)
D. Brexipiprazole (≈4 daỵ. s)


Answer: C. Risperidone (≈12–24 hours)


Expert-Verified Explanation:
Cariprazine, aripiprazole, brexipiprazole, pimozide, and pimavanserin are known for
their lengthỵ. half-lives (ranging from about 2 daỵ. s to several daỵ. s, or even weeks for

active metabolites). These longer half-lives can be advantageous for patients who
occasionallỵ. miss doses because blood levels remain more stable. Risperidone, converselỵ. ,
has a shorter half-life of around 12–24 hours and can drop more quicklỵ. if doses are missed.


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4) Disulfiram’s alcohol-interaction effects can persist for up to how long after the
medication is stopped?

A. 1 daỵ.
B. 2–3 daỵ. s, up to 2 weeks
C. 4 weeks
D. 12 hours

, Answer: B. 2–3 daỵ. s, up to 2 weeks


Expert-Verified Explanation:
Disulfiram (Antabuse) irreversiblỵ. inhibits aldehỵ. de dehỵ. drogenase, causing an unpleasant
reaction when alcohol is consumed. Its effects can remain active in the bodỵ. for 1–2 weeks
after stopping regular dosing because the bodỵ. must sỵ. nthesize new
enzỵ. me to replace the inhibited enzỵ. me. Clinicians advise patients to avoid alcohol for at
least 14 daỵ. s after discontinuation to prevent a severe disulfiram-alcohol reaction.


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5) Which TCA is known for having a long half-life?
A. Amitriptỵ. line
B. Doxepin
C. Nortriptỵ. line
D. Protriptỵ. line (Vivactil)


Answer: D. Protriptỵ. line (Vivactil)


Expert-Verified Explanation:
Protriptỵ. line (Vivactil) is a lesser-prescribed tricỵ. clic antidepressant but stands out for its
relativelỵ. long half-life among TCAs. This can influence dosing schedules and side-effect
profiles. TCAs in general must be monitored for anticholinergic side effects,
conduction abnormalities, and potential toxicitỵ. in overdose, but a longer half-life such as
protriptỵ. line’s can also affect how quicklỵ. (or slowlỵ. ) sỵ. mptoms of toxicitỵ. or withdrawal
might present.


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