HESI PHARMACOLOGY PRACTICE TEST – NURSING PHARMACOLOGY REVIEW – COMPLETE
PRACTICE QUESTIONS AND RATIONALES A+ VERIFIED LATEST VERSION
1. The nurse reviews the new prescription, phenelzine (Nardil), a monoamine
oxidase inhibitor (MAOI), for a client with depression on the psychiatric unit.
Which information is most important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose: A
2. The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first
time. What side effects should the nurse assess thr client during the initial
dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia: B
3. While reviewing the client's electronic medical record (EMR), the nurse as-
sesses a client who is at risk for a possible interaction with an over-the-counter
(OTC) decongestant. Which client health history should the nurse report to the
health care provider concerning the OTC medication? (Select all that apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucome
C. Chronic hypertension
D. Rheumatoid arthritis
E. Crohn's disease: B,C
4. A client prescribed ipratropium reports nausea, blurred vision, headaches,
and insomnia after using the inhaler. Which action should the nurse imple-
ment first?
A. Withhold the medication and report symptoms and vital signs to the health-
care provider
, HESI PHARMACOLOGY PRACTICE TEST – NURSING PHARMACOLOGY REVIEW – COMPLETE
PRACTICE QUESTIONS AND RATIONALES A+ VERIFIED LATEST VERSION
B. Give PRN medication for nausea and vomiting and evaluate client in 30
minutes
C. reassure client that the ipratropium given will alleviate the symptoms
D. Delay administration of ipratropium until the next maintenance medication
is scheduled: A
5. A client diagnosed with multiple sclerosis is experiencing profound weak-
ness, blurry vision, and shooting pains in both legs. Which medication is
considered the best course of treatment for the nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically: A
6. The nurse administers 30 mL of lactulose for a client with stage 2 hepatic
encephalopathy. Which assessment finding would indicate the medication is
being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification: A
7. The nurse is teaching a client who is newly diagnosed with type 1 diabetes
about neutral protamine Hagedor (NPH) insulin. Which statement by the client
indicates an understanding of how the medication works?
A. It facilitates the transport of glucose into the cells
B. It stimulates the function of beta cells in the pancreas
C. It increases the intracellular receptor site sensitivity
D. It delays the carbohydrate digestion and absorption: A
8. The nurse should withhold which medication if a client reports nausea,
vomiting, and diarrhea?
, HESI PHARMACOLOGY PRACTICE TEST – NURSING PHARMACOLOGY REVIEW – COMPLETE
PRACTICE QUESTIONS AND RATIONALES A+ VERIFIED LATEST VERSION
A. Colchicine (Mitigare, Colcrys)
B. Erythromycin (E-mycin)
C. Naproxen (Aleve, Naprosyn)
D. Labetolol (Normodyne): A
9. A client newly prescribed esomeprazole for gastroesophageal reflux disease
(GERD) asks the nurse how the medication will help. Which is the best expla-
nation to provide the client?
A. It will promote rapid tissue healing
B. It will increase gastric emptying
C. It will improve esophageal peristalsis
D. It will neutralize gastric secretions: A
10. A nurse is providing medication education for a client prescribed a
beta-blocking agent for treatment of glaucoma. Which statement by the client
demonstrates an understanding of the mechanism of the medication?
A. It inhibits the aqueous humor production
B. It enhances the aqueous humor outflow
C. It increases the intraocular pressure
D. It prevents extraocular infection: A
11. A nurse is planning a teaching session for a client newly prescribed a miotic
drug for the treatment of glaucoma. Which information should the nurse
include in the teaching session?
A. The medication enhances the aqueous humor outflow
B. The medication inhibits the aqueous humor production
C. The medication dilates the pupils
D. The medication prevents extraocular infection: A
12. The healthcare provider (HCP) prescribes a medication for an older adult
client who is reporting insomnia, and the HCP instructs the client to return in
two weeks. The nurse should question which prescription?
PRACTICE QUESTIONS AND RATIONALES A+ VERIFIED LATEST VERSION
1. The nurse reviews the new prescription, phenelzine (Nardil), a monoamine
oxidase inhibitor (MAOI), for a client with depression on the psychiatric unit.
Which information is most important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose: A
2. The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first
time. What side effects should the nurse assess thr client during the initial
dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia: B
3. While reviewing the client's electronic medical record (EMR), the nurse as-
sesses a client who is at risk for a possible interaction with an over-the-counter
(OTC) decongestant. Which client health history should the nurse report to the
health care provider concerning the OTC medication? (Select all that apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucome
C. Chronic hypertension
D. Rheumatoid arthritis
E. Crohn's disease: B,C
4. A client prescribed ipratropium reports nausea, blurred vision, headaches,
and insomnia after using the inhaler. Which action should the nurse imple-
ment first?
A. Withhold the medication and report symptoms and vital signs to the health-
care provider
, HESI PHARMACOLOGY PRACTICE TEST – NURSING PHARMACOLOGY REVIEW – COMPLETE
PRACTICE QUESTIONS AND RATIONALES A+ VERIFIED LATEST VERSION
B. Give PRN medication for nausea and vomiting and evaluate client in 30
minutes
C. reassure client that the ipratropium given will alleviate the symptoms
D. Delay administration of ipratropium until the next maintenance medication
is scheduled: A
5. A client diagnosed with multiple sclerosis is experiencing profound weak-
ness, blurry vision, and shooting pains in both legs. Which medication is
considered the best course of treatment for the nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically: A
6. The nurse administers 30 mL of lactulose for a client with stage 2 hepatic
encephalopathy. Which assessment finding would indicate the medication is
being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification: A
7. The nurse is teaching a client who is newly diagnosed with type 1 diabetes
about neutral protamine Hagedor (NPH) insulin. Which statement by the client
indicates an understanding of how the medication works?
A. It facilitates the transport of glucose into the cells
B. It stimulates the function of beta cells in the pancreas
C. It increases the intracellular receptor site sensitivity
D. It delays the carbohydrate digestion and absorption: A
8. The nurse should withhold which medication if a client reports nausea,
vomiting, and diarrhea?
, HESI PHARMACOLOGY PRACTICE TEST – NURSING PHARMACOLOGY REVIEW – COMPLETE
PRACTICE QUESTIONS AND RATIONALES A+ VERIFIED LATEST VERSION
A. Colchicine (Mitigare, Colcrys)
B. Erythromycin (E-mycin)
C. Naproxen (Aleve, Naprosyn)
D. Labetolol (Normodyne): A
9. A client newly prescribed esomeprazole for gastroesophageal reflux disease
(GERD) asks the nurse how the medication will help. Which is the best expla-
nation to provide the client?
A. It will promote rapid tissue healing
B. It will increase gastric emptying
C. It will improve esophageal peristalsis
D. It will neutralize gastric secretions: A
10. A nurse is providing medication education for a client prescribed a
beta-blocking agent for treatment of glaucoma. Which statement by the client
demonstrates an understanding of the mechanism of the medication?
A. It inhibits the aqueous humor production
B. It enhances the aqueous humor outflow
C. It increases the intraocular pressure
D. It prevents extraocular infection: A
11. A nurse is planning a teaching session for a client newly prescribed a miotic
drug for the treatment of glaucoma. Which information should the nurse
include in the teaching session?
A. The medication enhances the aqueous humor outflow
B. The medication inhibits the aqueous humor production
C. The medication dilates the pupils
D. The medication prevents extraocular infection: A
12. The healthcare provider (HCP) prescribes a medication for an older adult
client who is reporting insomnia, and the HCP instructs the client to return in
two weeks. The nurse should question which prescription?
