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FINAL EXAM ADVANCED PATHOPHYSIOLOGY, PATHOPHYSIOLOGY FINALS QUESTIONS AND CORRECT ANSWERS

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Master your advanced pathophysiology final exam with this comprehensive collection of over 150 practice questions and correct answers, designed for nurse practitioners, graduate nursing students, and medical professionals. This resource covers high-yield topics including cellular biology (lysosomes, peroxisomes, mitochondria, apoptosis), genetics and epigenetics (Down syndrome, Klinefelter, Turner, cystic fibrosis, oncogenes, tumor suppressor genes), immunology and inflammation (complement pathways, exotoxins, endotoxins, HIV, AIDS), endocrinology (Graves disease, type 1 and type 2 diabetes, DKA, HHNKS, Cushing syndrome, acromegaly, hypothyroidism), neurology (multiple sclerosis, spinal cord injury, autonomic hyperreflexia, myasthenia gravis), cardiology (angina types, valvular disorders, pericarditis, heart failure), pulmonology (asthma, COPD, pulmonary embolism, respiratory distress syndrome), hematology (aplastic anemia, hemolytic disease of the newborn, leukemia), nephrology (nephrotic syndrome, glomerulonephritis, renal cell carcinoma), and gastroenterology (hepatitis, celiac disease, ulcerative colitis, Crohn disease, GERD). Each question mirrors the difficulty of actual final exams, providing correct answers to reinforce key pathophysiological concepts for certification and clinical success.

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Institution
Advanced Pathophysiology
Course
Advanced pathophysiology

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FINAL EXAM ADVANCED PATHOPHYSIOLOGY, PATHOPHYSIOLOGY
FINALS QUESTIONS AND CORRECT ANSWERS




physiologic jaundice - ANS✅✅A 3-day old infant is noted to have a
mildly elevated unconjugated bilirubin level and icterus. Your concern is
that this child may have:
a. physiologic jaundice
b. kernicterus
c. glucose-6-phosphate dehydrogenase deficiency
d. pathologic jaundice


Lysosomes - ANS✅✅Which cell component is capable of cellular
autodigestion when it is released during cell injury?
a. lysosomes
b. ribosomesc. smooth endoplasmi
c reticulum
d. Golgi complex


Which component of the cell produces hydrogen peroxide (H2O2) by using
oxygen to remove hydrogen atoms from specific substrates in an oxidative
reaction?


A) lysosomes
B) peroxisomes
C) ribosomes

,D) ox hydrosomes - ANS✅✅Ans: B- peroxisomes


Contain organelles and complex internal membranes - ANS✅✅The
difference between eukaryotes and prokaryotes is that eukaryotes:
a. all of these answers are correct
b. are smaller in size
c. contain organelles
d. have no nuclear membrane


What is a consequence of plasma membrane damage to the mitochondria?


A) enzymatic digestion halts deoxyribonucleic acid (DNA) synthese
B) influx of calcium ions halts adenosine triphosphate (ATP) production
C) edema from an influx in sodium causes a reduction in ATP production
D) potassium shifts out of the mitochondria, which destroys the
infrastructure - ANS✅✅Ans: B- influx of calcium ions halts adenosine
triphosphate (ATP) production


Packages protein for secretion to the outside of the cell - ANS✅✅Which
of the following is function of Golgi?
a. Packages protein for secretion to the outside of the cell
b. Produces ATP for cell function
c. Contains hydrolytic enzymes
d. Is the site of protein synthesis in a cell


Which statement is a description of one of the characteristics of apoptosis?

,A) apoptosis involves programmed cell death of scattered singel cells
B) apoptosis is characterized by the swelling of the nucleus and the
cytoplasm
C) apoptosis involves unpredictable patterns of cell death
D) apoptosis results in benign malignancies - ANS✅✅Ans: A- apoptosis
involves programmed cell death of scattered singel cells


During cell injury caused by hypoxia, sodium and water move into the cell
because:


A) during cell injury cause by hypoxia, sodium and water move into the cell
because:
B) the pump that transports sodium out of the cell cannot function because
of a decrease in adenosine triphosphate (ATP) levels
C) the osmotic pressure is increased, which pulls additional sodium across
the cell membrane
D) oxygen is not available to bind with sodium to maintain it outside of the
cell - ANS✅✅Ans: C- the osmotic pressure is increased, which pulls
additional sodium across the cell membrane


Is the site of protein synthesis in a cell - ANS✅✅Which of the following is
function of the rough endoplasmic reticulum?
a. Contains hydrolytic enzymes
b. Is the site of protein synthesis in a cell
c. Packages protein for secretion to the outside of the cell
d. Produces ATP for cell function

, Obesity creates a greater risk for dehydration in people because:


A) adipose cells contain little water because fat is water repelling
B) the metabolic rates of obese adults are slower than those of lean adults
C) the rates of urine output of obese adults are higher than thos of lean
adults
D) the thirst receptors of the hypothalamus do not function effectively -
ANS✅✅Ans: A- adipose cells contain little water because fat is water
repelling


Epigenetic modifications - ANS✅✅What genetic process is likely
responsible for the occurrence of asthma in only one of a pair of identical
twins?
a. genomic imprinting
b. epigenetic modifications
c. methylation
d. transgenerational inheritance


RNA is synthesized from a DNA template - ANS✅✅Transcription is best
defined as a process by which
a. A base pair substitution results in a mutation of the amino acid sequence
b. DNA polymerase binds to the promoter site on RNA.
c. RNA directs the synthesis of ribosomes for protein synthesis
d. RNA is synthesized from a DNA template


nondisjunction error - ANS✅✅What is the most common cause of Down
syndrome?

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Institution
Advanced pathophysiology
Course
Advanced pathophysiology

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Uploaded on
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