Pharmacotherapeutics for Advanced Practice: A Practical Approach 5th Edition | Advanced Nursing Pharmacology Textbook

lOMoARcPSD|327 b 44 6 9
l1OM oARcPSD|327 b 441
b 69




Study Guide For
b b b




Pharmacotherapeutics For Advanced Practice: Ab b b b




PracticalApproach 5th Edition | Advanced
b b b b b b




Pharmacology Review Questions& Answers |
b b b b b b




APRN Exam Prep 2025/2026
b b b b

, lOMoARcPSD|327 b441 b69




TABLE OF CONTENT
b b




o Chapter 1: Issues for the Practitioner in Drug Therapy
b b b b b b b b




o Chapter 2: Pharmacokinetic Basis of Therapeutics and Pharmacodynamic Principles
b b b b b b b b




o Chapter 3: Impact of Drug Interactions and Adverse Events on Therapeutics
b b b b b b b b b b




o Chapter 4: Principles of Pharmacotherapy in Pediatrics, Pregnancy and Lactation
b b b b b b b b b




o Chapter 5: Pharmacotherapy Principles in Older Adults
b b b b b b




o Chapter 6: Principles of Antimicrobial Therapy
b b b b b




o Chapter 7: Pharmacogenomics b b




o Chapter 8: The Economics of Pharmacotherapeutics
b b b b b




o Chapter 9: Principles of Pharmacology in Pain Management
b b b b b b b




o Chapter 10: Pain Management in Opioid Use Disorder (OUD) Patients
b b b b b b b b b




o Chapter 11: Cannabis and Pain Management
b b b b b




o Chapter12: Dermatitis b b




o Chapter 13: Bacterial, Fungal, and Viral Infections of the Skin
b b b b b b b b b




o Chapter14: Psoriasis b b




o Chapter15: AcneVulgaris and Rosacea
b b b b b




o Chapter 16: Ophthalmic Disorders
b b b




o Chapter17: OtitisMedia and OtitisExterna
b b b b b b




o Chapter18: Hypertension b b




o Chapter19: Hyperlipidemia b b




o Chapter 20: Chronic Stable Angina and Myocardial Infarction
b b b b b b b




o Chapter 21: Heart Failure b b b




o Chapter22: Arrhythmias b b




o Chapter 23: Respiratory Infections
b b b




o Chapter 24: Asthma and Chronic Obstructive Pulmonary Disease
b b b b b b b




o Chapter 25: Gastric, Functional and Inflammatory Bowel Disorders
b b b b b b b b




o Chapter 26: Gastroesophageal Reflux Disease and Peptic Ulcer Disease
b b b b b b b b




o Chapter27:LiverDiseases b b b




o Chapter 28: Urinary Tract Infection
b b b b




o Chapter 29: Prostatic Disorders and Erectile Dysfunction
b b b b b b b




o Chapter30: Overactive Bladder b b b




o Chapter 31: Sexually Transmitted Infections
b b b b




o Chapter 32: Osteoarthritis and Gout
b b b b




o Chapter33: Osteoporosis b b




o Chapter 34: Rheumatoid Arthritis
b b b




o Chapter35: Headaches b b




o Chapter 36: Seizure Disorders
b b b




o Chapter 37: Alzheimer’s Disease
b b b




o Chapter 38: Parkinson Disease
b b b




o Chapter 39: Major Depressive Disorder and Bipolar Disorders
b b b b b b b




o Chapter 40: Anxiety Disorders b b b




o Chapter 41: Sleep Disorders b b b




o Chapter 42: Attention Deficit Hyperactivity Disorder
b b b b b




o Chapter 43: Substance Use Disorders
b b b b




o Chapter 44: Diabetes Mellitusb b b




o Chapter 45: Thyroid and Parathyroid Disorders
b b b b b




o Chapter 46: Allergies and Allergic Reactions o
b b b b b b




Chapter 47: Human Immunodeficiency Virus o
b b b b b b




Chapter 48: Organ Transplantation
b b b b




o Chapter 49: Pharmacotherapy for Select Thromboembolic Disorders
b b b b b b




o Chapter50: Anemias b b




o Chapter51:Immunizations b b




o Chapter 52: Smoking Cessation
b b b




o Chapter53: Weight Loss b b b




o Chapter54: Contraception b b

, lOMoARcPSD|327 b441 b69




o Chapter55: Menopause b b




o Chapter56: Vaginitis b b




Chapter 1Issuesforthe Practitioner in Drug Therapy
b b b b b b b b




MULTIPLECHOICE b




1. Nursepractitioner prescriptive authorityisregulated by:
b b b b b b




A. TheNational Councilof StateBoards of Nursing
b b b b b b b




B. TheU.S.DrugEnforcement Administration
b b b b




C. The State Board ofNursing for each state
b b b b b b b




D. The State Board of Pharmacy b b b b




ANS: C b PTS: 1

2. PhysicianAssistant (PA) prescriptiveauthority is regulated by:
b b b b b b b




A. TheNational Councilof StateBoards of Nursing
b b b b b b b




B. TheU.S.DrugEnforcement Administration
b b b b




C. The State Board of Nursing b b b b




D. The State Board of Medical Examiners
b b b b b




ANS: D b PTS: 1

3. Clinicaljudgment inprescribingincludes:
b b b b




A. Factoring inthe costto the patient ofthemedication prescribed b b b b b b b b b b




B. Always prescribing the newest medication available for the disease process
b b b b b b b b b




C. Handing out drug samples to poor patients b b b b b b




D. Prescribingall genericmedications tocut costs b b b b b b




ANS: A b PTS: 1

4. Criteriafor choosingan effectivedrugforadisorder include:
b b b b b b b b b




A. Askingthepatientwhatdrugtheythink wouldworkbestforthem
b b b b b b b b b b b




B. Consultingnationallyrecognizedguidelinesfordisease management b b b b b b




C. Prescribing medications that are available as samples before writing a prescription b b b b b b b b b b




D. FollowingU.S.Drug EnforcementAdministration(DEA)guidelinesfor b b b b b b b




prescribing
b




ANS: B b PTS: 1

5. Nurse practitioner practice maythrive under health-carereform due to:
b b b b b b b b b




A. The demonstrated ability of nurse practitioners to control costs and improve patient
b b b b b b b b b b b




outcomes
b




B. Thefactthatnursepractitionerswillbeabletopracticeindependently
b b b b b b b b b b




C. The fact that nurse practitioners will have full reimbursement under health-care
b b b b b b b b b b




reform
b




D. The abilityto shiftaccountabilityforMedicaidtothestate level
b b b b b b b b b b




ANS: A b PTS: 1

, lOMoARcPSD|327 b441 b69




Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
b b b b b b




MULTIPLECHOICE b




1. Apatient’snutritionalintakeandlabworkreflectshypoalbuminemia.Thisis criticalto
b b b b b b b b b b b b




bprescribingbecause:
A. Distribution of drugs totargettissue may beaffected b b b b b b b b




B. Thesolubility ofthe drug will not matchthe siteofabsorption
b b b b b b b b b b b




C. Therewill beless freedrugavailable togenerate aneffect b b b b b b b b b b




D. Drugsbound toalbumin arereadilyexcreted bythekidney b b b b b b b b b




ANS: A b PTS: 1

2. Drugs that haveasignificantfirst-passeffect:
b b b b b b




A. Mustbegivenbythe enteral(oral)routeonly b b b b b b b b




B. Bypassthehepaticcirculation b b b




C. Are rapidly metabolized bytheliver and mayhave little if anydesired action
b b b b b b b b b b b b b




D. Areconvertedbythe livertomoreactiveandfat-solubleforms
b b b b b b b b b b




ANS: C b PTS: 1

3. Theroute ofexcretionof avolatiledrug willlikelybe:
b b b b b b b b b b




A. Thekidneys b




B. Thelungs b




C. The bile and feces b b b




D. The skin b




ANS: B b PTS: 1

4. Medroxyprogesterone (DepoProvera)isprescribedIM tocreatea storagereservoir ofthe drug. b b b b b b b b b b b b b




Storagereservoirs:
b b




A. Assurethat the drug willreach its intendedtarget tissue b b b b b b b b b




B. Arethe reasonfor giving loadingdoses b b b b b b




C. Increasethelengthoftimea drug isavailableandactive b b b b b b b b b b




D. Aremost common in collagentissues b b b b b




ANS: C b PTS: 1

5. The NP chooses to give cephalexin every 8 hours based on knowledgeof thedrug’s:
b b b b b b b b b b b b b b




A. Propensitytogotothetarget receptor b b b b b b




B. Biologicalhalf-life b




C. Pharmacodynamics
D. Safetyand sideeffects b b b




ANS: B b PTS: 1

6. Azithromycindosingrequiresthefirstday’sdosebetwicethose ofthe other4 days ofthe b b b b b b b b b b b b b b b b




prescription.Thisisconsideredaloadingdose.Aloadingdose:
b b b b b b b b b b




A. Rapidly achievesdruglevelsinthetherapeuticrange b b b b b b b




B. Requiresfour tofive half-livesto attain b b b b b b




C. Is influenced by renal function
b b b b