NR 546 NEWEST& LATEST EXAM VERSION OF () With Expected real and comprehensive Questions and Revised Correct Answers Guarantee Pass A+.

NR 546 NEWEST AND LATEST EXAM
VERSION OF (2026-2027) With
Expected real and comprehensive
Questions and Revised Correct
Answers Guarantee Pass A+
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,Prefrontal Cortex Symptoms of MDD - correct ans:Concentration

Mental Fatigue

Mood



PFC & Amygdala Symptoms of MDD - correct ans:Guilt

Suicidality

Worthlessness



Striatum Symptoms of MDD - correct ans:Physical fatigue



Nucleus Accumbens Symptoms of MDD - correct ans:Pleasure interests



Hypothalamus Symptoms of MDD - correct ans:Sleep

Appetite



Thalamus & Hypothalamus Symptoms of Mania - correct ans:Decreased sleep/arousal



Striatum Symptoms of Mania - correct ans:Motor/agitation



Prefrontal cortex (PFC) Symptoms of Mania - correct ans:Risk-taking

Talkative/pressured speech



Nucleus Accumbens & PFC Symptoms of Mania - correct ans:Racing thoughts, grandiosity



PFC & Amygdala Symptoms of Mania - correct ans:Mood



Medication Management - correct ans:SSRI-Selective Serotonin Reuptake Inhibitors

*Inhibit 5 HT reuptake

,SNRI-Serotonin Norepinephrine Reuptake Inhibitors

*inhibit 5-HT reuptake

*inhibit NE reuptake (increase energy, focus)

*increase DA in prefrontal cortex (increase cognition)

NDRI-Norepinephrine Dopamine Reuptake inhibitors

*inhibit DA reuptake (increase alertness, motivation)

*inhibit NE reuptake (increase energy)

SARI-Serotonin Antagonist Reuptake Inhibitors



Selective Serotonin Reuptake Inhibitors (SSRIs): Most adverse effects will subside after 4-5 days once the
body adjusts to increased serotonin levels. - correct ans:diarrhea

headache

weight gain

sexual side effects



Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): Medications should not be abruptly stopped to
avoid discontinuation symptoms. NE effects of the medication may increase anxiety in some clients.
Report worsening anxiety to the provider. - correct ans:elevated blood pressure

anxiety

insomnia

constipation



Norepinephrine Dopamine Reuptake Inhibitors (NDRI): Take medication in the morning. Stop taking
medication if seizures occur. Stop taking medication if anxiety is noted. - correct ans:agitation

headache

dry mouth

constipation

weight loss



escitalopram (Lexapro) SSRI - correct ans:no known drug interactions

, best tolerated SSRI

27-32 hour half-life good for forgetful prone clients

least CYP reactions

Substrate for 3A4



citalopram (Celexa) SSRI - correct ans:mild antihistamine effects; Half-Life: 23-45 hours

Weak Inhibitor of 2D6



fluoxetine (Prozac) SSRI - correct ans:longest half-life

Use caution in patients with comorbid anxiety due to risk for activation and panic attacks

Half-Life: 2-3 days parent, 2 week metabolite

Inhibits 2D6 and 3A4



paroxetine (Paxil) SSRI - correct ans:also treats social anxiety and insomnia

associated with weight gain

will experience withdrawal with missed dose or abrupt stop

Half-Life: 24 hours

Inhibits 2D6



fluvoxamine (Luvox) SSRI - correct ans:treats anxious depression smokers require an increased dose

Half-Life: 9-28 hours

Inhibits 3A4, 2C9, 1A2



sertraline (Zoloft) SSRI - correct ans:also treats social anxiety and hypersomnolence

Half-Life: 22-36 hour parent; 62-104 hour metabolite

Inhibits 2D6 and 3A4 weakly at low doses



venlafaxine (Effexor) - correct ans:treats both depression and anxiety disorders, ensure trial of higher
dose before switching to a different medication