NBME CBSE (USMLE STEP 1)
TESTBANK EXAM QUESTIONS WITH
100% CORRECT ANSWERS |
VERIFIED || ACTUAL EXAM 2026
TEST!! GRADED A+ | 2026|2027 EXAM
UPDATE
70yomMmdiesminmammotormvehiclemcollision.mWasmundergoingmevaluationmformoccultmbloodminmthem
stool.mPhotomofmtransversemcolonmshown.mDx?m-mCORRECTmANSWERmTubularmadenoma
38yomMmwithm1-
weekmhxmofmwatery,mitchymeyesmandmamrunnymnose.mPhysicalmshowsminflamedmnasalmmucosa.mNomc
ongestionminmlowermlung.mPharmacotherapy?m-mCORRECTmANSWERmLoratadine
16yomgirlmwithm3-daymhxmofmfever,mnonproductivemcough,mandmfatigue.mTm38.3,mPm88/min,mBPm102-
70.mPEmshowsmpalemconjunctivae.mCXRmshowsmbilateralminterstitialminfiltrates.mBloodmspontaenous
lymagglutinatesmwhilemawaitingmtransportmtomthemlaboratory.mAntibodymisotypesmcausingmagglutin
ation?m-mCORRECTmANSWERmIgM
24yomMmwithmsmallmtendermblistersmonmhismpenism3mdaysmaftermunprotectedmsex.mPhotographmsho
wn.mCausalmagent?m-mCORRECTmANSWERmHSV-2
42yomFmwithm3-
yearmhxmofmanmintermittentmfacialmrash,mincludingmthemforehead,meyelids,mnose,mandmcheeks.mRash
mseemsmtombemgettingmworsemsincemshemmovedmfrommNewmYorkmtomFloridamlastmyear.mSpicymfoodsm
precipitatemamflushingmreactionmthatmseemsmtomexacerbatemthemrash.mPEmshowsmerythemamovermt
hemnosemandmcheeks,mwithmscatteredmtelangiectasiasmandmamfewmpapules.mDx?m-
mCORRECTmANSWERmRosacea
,53yomMmreturnedmfrommAfrica,mhasmfever,mheadache,mandmabdominalmdiscomfort.mReceivedmappr
opriatemvaccinationsmpriormtomthemtrip.mTm39.4C.mAmwright-
stainedmperipheralmsmearmshown.mDx?m-mCORRECTmANSWERmMalaria
68yomFmwithmT2DMmandmhypertensionmthatmhasmbeenmpoorlymcontrolledmdespitemhydrochlorothia
zidemtreatment.mBPm150/96,mLabsmshowmserummglucosemconcentrationmofm130mandmproteinuria.mI
nmadditionmtomcurrentmRx,mwhichmismmostmappropriatempharmacotherapy?m-
mCORRECTmANSWERmLisinopril
66yomMmwithmstagemIVmcolonmcancermwithm3-
daymhxmofmseveremdiarrheamaftermreceivingmchemotherapymwithmfluorouracil,mleucovorin,mandmIrin
otecan.mprescribedmopioidmantidiarrhealmagentmwithmnomCNSmeffects.mWhichmmed?m-
mCORRECTmANSWERmLoperamide
35yomMminmEDmwithm2-
hourmhxmofmsevermfatiguemandmdizziness.mHadmprofuse,mwaterymdiarrheamform8mhoursmdespitemamla
ckmofmoralmintake.mRecentlymreturnedmfrommammedicalmreliefmtripmtomamremovemvillageminmHondura
s.mTm36.7mC,mPm122/min,mBPm90/50.mPEmshowsmdrymskinmandmdecreasedmcapillarymrefill.mStoolmform
occultmbloodmismnegative;mstoolmismgraymandmturbid.mGrammstainmshowsmgram-negative,mcomma-
shapedmbacteria;mnomerythrocytesmofmleukocytes.mMOAmofmtoxin?m-
mCORRECTmANSWERmActivationmofmadenylylmcyclase
59yomFmwithmgradualmonsetmofmlackmofmmusclemcontrolminmhermleftmarmmandmleg.mSxm1mmomagomaft
ermdxmwithmmetastaticmbreastmcancer.mPEmshowsmataxiamofmleftmuppermandmlowermextremities.mMu
sclemstrength,mDTR,msensation,mproprioceptionmnormal.mMetastaticmtumorminmwhichmlocation?m-
mCORRECTmANSWERmcerebellum
Newbornmdeliveredmatm38mweeks'mgestationmweighsm1800mg.mPEmshowsmpetechialmrash,mmicrocep
haly,mandmhepatosplenomegaly.mSerologicmtestmformCMV:mIgGm+minmmother,m+minmnewborn;mIGMm-
minmmother,m+minmnewborn.mExplanation?m-
mCORRECTmANSWERmCongenitalmcytomegalovirusminfection
,Femalemnewbornmismdeliveredmatm38mweeks'mgestation.mApgarm8mandm8matm1/5mmin.mPEmshowsmam
bulging,mfluod0filledmmassmapproximatelym5mcmminmdiameterminmthemmidlinemovermthemlumbosacr
almregion.mNomspontaneousmmovementsmofmthemlowermextremities.mAbnormalitymmostmlikelymocc
urredmbecausemofmabnormalmdevelopmentmduringmwhichmperiodsmofmpostconceptionm(inmdays)?m-
mCORRECTmANSWERm15mtom40
64yomMminmEDm3mhoursmaftermSOBmwithmexertionmandmextrememfatigue.mHasmischemicmheartmdisea
se.mPm125/min,mBPm105/60.mECGmshowsmatrialmfibrillation.mIntravenousmibutilidemismadministered.m
Tenmminutesmlater,mECGmshowsmnormalmsinusmrhythm.mRiskmformwhichmdrugmeffectminmthemnextm6m
hours?m-mCORRECTmANSWERmtorsadesmdempointes
65yomFmwithm20-
yearmhxmofmosteoarthritismofmthemhandsmnowmhasmpainmradiatingmdownmthemdistalmanteriormthigh,m
knee,mmedialmleg,mandmfood.mBonymoutgrowthmofmvertebraemcompressingmonemofmthemspinalmnerv
esmismsuspected.mNervemrootminmwhichmintervertebralmforaminamismeffected?m-
mCORRECTmANSWERmL3mtomL4
38yomMmwithm3-
yearmhxmofmT2DM.mTakingmanmoralmantihyperglycemicmagent,mhemhasmtriedmdietmandmexercise.mBMI
m32.mPEmnormal.mHbmA1cmism10%.mPhysicianmrecommendsminitiationmofminsulinminjections.mRespon
ds,m"Imknowmthatminsulinmwouldmhelpmcontrolmmymbloodmsugar.mButmamlotmofmpeopleminmmymfamilym
havemdiabetes,mandminsulinmmademthemmreallymsickmatmtimes.mPatientmismatmwhichmstagemofmchang
e?m-mCORRECTmANSWERmcontemplation
24yomMmwithm2-
daymhistorymofmanmitchymrashmonmhismarmsmandmlegs.mReturnedmfrommamcampingmtripminmthemwood
sm5mdaysmago.mPEmshowsmedematous,merythematousmrashmwithmlinearmvesicles.mCausemismactivatio
nmofmwhichmcellmtypes?m-mCORRECTmANSWERmTmlymphocytes
70yomMmfrommchinamwithmpoorlymdifferentiatedmmonoclonalmcarcinomamofmthemnasopharynx.mDN
Amprobesmofmneoplasticmcellsmaremmostmlikelymtomdetectmgenomemofmwhichmvirus?m-
mCORRECTmANSWERmEBV
, Epidemiologicmstudymofmanilinemdye,m500mworkersmwithmbladdermcancermandm200mworkersmwitho
ut.mExposedmtomanilinemdyes/HavemBladdermcancer:mYes/Yesm(250),mYes/Nom(50),mNo/Yesm(250),mN
o/Nom(150).mOddsmratio?m-mCORRECTmANSWERm3
24yomMmwithmhxmofmIVDAmcouldmnotmbemaroused.mFriendmreportsmthatmthempatientminjectedmhims
elfmwithmamdrugm6mhoursmago.mLabsmshowmdrugmconcentrationmofm0.3.mAssumingmfirst-ordermone-
compartmentmkinetics,mhasmamhalf-
lifemofm2mhours,mandmamvolumemofmdistributionmofm200mLminmthismpatient.mWhatmismquantitymofmdru
gm(inmmg)minjected?m-mCORRECTmANSWERm480
Compoundmismtakenmupmbymbacterialmcells.mNomenergymismnecessarymformuptake,mandmthemcompou
ndmismnotmconcentratedminmthemcell.mWhichmdescribesmthismmechanismmofmtransport?m-
mCORRECTmANSWERmcarrier-mediatedmdiffusion
Newbornmhasmmalemgenitalmductsmbutmfemalemexternalmgenitalia.mCytogeneticmanalysismshowsmam
46,XYmkaryotype,mandmgeneticmtestingmshowsmammutationmofmthemgenemencodingm5alpha-
reductase.mInmabsencemofmthismmutation,mlabiammajoramwouldmhavembeen?m-
mCORRECTmANSWERmscrotum
StudymdesignedmtomevaluatemthemefficacymofmcoenzymemQ10minmimprovingmcardiacmoutputminmpati
entsmwithmCHF.mSixtympatientsmwithmCHFmaremrecruited.mEachmassignedmbymcoinmtossmtomonemofmtw
omgroups.mDesign?m-mCORRECTmANSWERmrandomizedmclinicalmtrial
12yomboymimmersedmupmtomhismneckminm60Fmwatermform20mminutes.mPhysiologicalmchanges?m-
mCORRECTmANSWERmCentralmbloodmvolumemINCREASED,mADHm(vasopressin)mDECREASED,mAtrialm
NatriureticmPeptidemINCREASED?mCm(block3,mq23)
Randomizedmcontrolledmstudymofm2000mpatientsmwithminsomniamismconductedmtomevaluatemthemef
ficacymofmamnewmmedicationmtomtreatmthismcondition.mTenmsubjectsmfrommbothmthemcontrolmandmtr
eatmentmgroupsmdomnotmcompletemthemstudymaremnotmincludedminmthemanalysis.mTreatmentmgrou
pmablemtomfallmasleepm5mminutesmfastermthanmcontrolm(p=0.001).mNeithermgroupmreportmanmimprov
ementminmqualitymofmlife.mConcludemthatmnewmmedmismefficaciousminmtreatingminsomnia.mTypemofme
TESTBANK EXAM QUESTIONS WITH
100% CORRECT ANSWERS |
VERIFIED || ACTUAL EXAM 2026
TEST!! GRADED A+ | 2026|2027 EXAM
UPDATE
70yomMmdiesminmammotormvehiclemcollision.mWasmundergoingmevaluationmformoccultmbloodminmthem
stool.mPhotomofmtransversemcolonmshown.mDx?m-mCORRECTmANSWERmTubularmadenoma
38yomMmwithm1-
weekmhxmofmwatery,mitchymeyesmandmamrunnymnose.mPhysicalmshowsminflamedmnasalmmucosa.mNomc
ongestionminmlowermlung.mPharmacotherapy?m-mCORRECTmANSWERmLoratadine
16yomgirlmwithm3-daymhxmofmfever,mnonproductivemcough,mandmfatigue.mTm38.3,mPm88/min,mBPm102-
70.mPEmshowsmpalemconjunctivae.mCXRmshowsmbilateralminterstitialminfiltrates.mBloodmspontaenous
lymagglutinatesmwhilemawaitingmtransportmtomthemlaboratory.mAntibodymisotypesmcausingmagglutin
ation?m-mCORRECTmANSWERmIgM
24yomMmwithmsmallmtendermblistersmonmhismpenism3mdaysmaftermunprotectedmsex.mPhotographmsho
wn.mCausalmagent?m-mCORRECTmANSWERmHSV-2
42yomFmwithm3-
yearmhxmofmanmintermittentmfacialmrash,mincludingmthemforehead,meyelids,mnose,mandmcheeks.mRash
mseemsmtombemgettingmworsemsincemshemmovedmfrommNewmYorkmtomFloridamlastmyear.mSpicymfoodsm
precipitatemamflushingmreactionmthatmseemsmtomexacerbatemthemrash.mPEmshowsmerythemamovermt
hemnosemandmcheeks,mwithmscatteredmtelangiectasiasmandmamfewmpapules.mDx?m-
mCORRECTmANSWERmRosacea
,53yomMmreturnedmfrommAfrica,mhasmfever,mheadache,mandmabdominalmdiscomfort.mReceivedmappr
opriatemvaccinationsmpriormtomthemtrip.mTm39.4C.mAmwright-
stainedmperipheralmsmearmshown.mDx?m-mCORRECTmANSWERmMalaria
68yomFmwithmT2DMmandmhypertensionmthatmhasmbeenmpoorlymcontrolledmdespitemhydrochlorothia
zidemtreatment.mBPm150/96,mLabsmshowmserummglucosemconcentrationmofm130mandmproteinuria.mI
nmadditionmtomcurrentmRx,mwhichmismmostmappropriatempharmacotherapy?m-
mCORRECTmANSWERmLisinopril
66yomMmwithmstagemIVmcolonmcancermwithm3-
daymhxmofmseveremdiarrheamaftermreceivingmchemotherapymwithmfluorouracil,mleucovorin,mandmIrin
otecan.mprescribedmopioidmantidiarrhealmagentmwithmnomCNSmeffects.mWhichmmed?m-
mCORRECTmANSWERmLoperamide
35yomMminmEDmwithm2-
hourmhxmofmsevermfatiguemandmdizziness.mHadmprofuse,mwaterymdiarrheamform8mhoursmdespitemamla
ckmofmoralmintake.mRecentlymreturnedmfrommammedicalmreliefmtripmtomamremovemvillageminmHondura
s.mTm36.7mC,mPm122/min,mBPm90/50.mPEmshowsmdrymskinmandmdecreasedmcapillarymrefill.mStoolmform
occultmbloodmismnegative;mstoolmismgraymandmturbid.mGrammstainmshowsmgram-negative,mcomma-
shapedmbacteria;mnomerythrocytesmofmleukocytes.mMOAmofmtoxin?m-
mCORRECTmANSWERmActivationmofmadenylylmcyclase
59yomFmwithmgradualmonsetmofmlackmofmmusclemcontrolminmhermleftmarmmandmleg.mSxm1mmomagomaft
ermdxmwithmmetastaticmbreastmcancer.mPEmshowsmataxiamofmleftmuppermandmlowermextremities.mMu
sclemstrength,mDTR,msensation,mproprioceptionmnormal.mMetastaticmtumorminmwhichmlocation?m-
mCORRECTmANSWERmcerebellum
Newbornmdeliveredmatm38mweeks'mgestationmweighsm1800mg.mPEmshowsmpetechialmrash,mmicrocep
haly,mandmhepatosplenomegaly.mSerologicmtestmformCMV:mIgGm+minmmother,m+minmnewborn;mIGMm-
minmmother,m+minmnewborn.mExplanation?m-
mCORRECTmANSWERmCongenitalmcytomegalovirusminfection
,Femalemnewbornmismdeliveredmatm38mweeks'mgestation.mApgarm8mandm8matm1/5mmin.mPEmshowsmam
bulging,mfluod0filledmmassmapproximatelym5mcmminmdiameterminmthemmidlinemovermthemlumbosacr
almregion.mNomspontaneousmmovementsmofmthemlowermextremities.mAbnormalitymmostmlikelymocc
urredmbecausemofmabnormalmdevelopmentmduringmwhichmperiodsmofmpostconceptionm(inmdays)?m-
mCORRECTmANSWERm15mtom40
64yomMminmEDm3mhoursmaftermSOBmwithmexertionmandmextrememfatigue.mHasmischemicmheartmdisea
se.mPm125/min,mBPm105/60.mECGmshowsmatrialmfibrillation.mIntravenousmibutilidemismadministered.m
Tenmminutesmlater,mECGmshowsmnormalmsinusmrhythm.mRiskmformwhichmdrugmeffectminmthemnextm6m
hours?m-mCORRECTmANSWERmtorsadesmdempointes
65yomFmwithm20-
yearmhxmofmosteoarthritismofmthemhandsmnowmhasmpainmradiatingmdownmthemdistalmanteriormthigh,m
knee,mmedialmleg,mandmfood.mBonymoutgrowthmofmvertebraemcompressingmonemofmthemspinalmnerv
esmismsuspected.mNervemrootminmwhichmintervertebralmforaminamismeffected?m-
mCORRECTmANSWERmL3mtomL4
38yomMmwithm3-
yearmhxmofmT2DM.mTakingmanmoralmantihyperglycemicmagent,mhemhasmtriedmdietmandmexercise.mBMI
m32.mPEmnormal.mHbmA1cmism10%.mPhysicianmrecommendsminitiationmofminsulinminjections.mRespon
ds,m"Imknowmthatminsulinmwouldmhelpmcontrolmmymbloodmsugar.mButmamlotmofmpeopleminmmymfamilym
havemdiabetes,mandminsulinmmademthemmreallymsickmatmtimes.mPatientmismatmwhichmstagemofmchang
e?m-mCORRECTmANSWERmcontemplation
24yomMmwithm2-
daymhistorymofmanmitchymrashmonmhismarmsmandmlegs.mReturnedmfrommamcampingmtripminmthemwood
sm5mdaysmago.mPEmshowsmedematous,merythematousmrashmwithmlinearmvesicles.mCausemismactivatio
nmofmwhichmcellmtypes?m-mCORRECTmANSWERmTmlymphocytes
70yomMmfrommchinamwithmpoorlymdifferentiatedmmonoclonalmcarcinomamofmthemnasopharynx.mDN
Amprobesmofmneoplasticmcellsmaremmostmlikelymtomdetectmgenomemofmwhichmvirus?m-
mCORRECTmANSWERmEBV
, Epidemiologicmstudymofmanilinemdye,m500mworkersmwithmbladdermcancermandm200mworkersmwitho
ut.mExposedmtomanilinemdyes/HavemBladdermcancer:mYes/Yesm(250),mYes/Nom(50),mNo/Yesm(250),mN
o/Nom(150).mOddsmratio?m-mCORRECTmANSWERm3
24yomMmwithmhxmofmIVDAmcouldmnotmbemaroused.mFriendmreportsmthatmthempatientminjectedmhims
elfmwithmamdrugm6mhoursmago.mLabsmshowmdrugmconcentrationmofm0.3.mAssumingmfirst-ordermone-
compartmentmkinetics,mhasmamhalf-
lifemofm2mhours,mandmamvolumemofmdistributionmofm200mLminmthismpatient.mWhatmismquantitymofmdru
gm(inmmg)minjected?m-mCORRECTmANSWERm480
Compoundmismtakenmupmbymbacterialmcells.mNomenergymismnecessarymformuptake,mandmthemcompou
ndmismnotmconcentratedminmthemcell.mWhichmdescribesmthismmechanismmofmtransport?m-
mCORRECTmANSWERmcarrier-mediatedmdiffusion
Newbornmhasmmalemgenitalmductsmbutmfemalemexternalmgenitalia.mCytogeneticmanalysismshowsmam
46,XYmkaryotype,mandmgeneticmtestingmshowsmammutationmofmthemgenemencodingm5alpha-
reductase.mInmabsencemofmthismmutation,mlabiammajoramwouldmhavembeen?m-
mCORRECTmANSWERmscrotum
StudymdesignedmtomevaluatemthemefficacymofmcoenzymemQ10minmimprovingmcardiacmoutputminmpati
entsmwithmCHF.mSixtympatientsmwithmCHFmaremrecruited.mEachmassignedmbymcoinmtossmtomonemofmtw
omgroups.mDesign?m-mCORRECTmANSWERmrandomizedmclinicalmtrial
12yomboymimmersedmupmtomhismneckminm60Fmwatermform20mminutes.mPhysiologicalmchanges?m-
mCORRECTmANSWERmCentralmbloodmvolumemINCREASED,mADHm(vasopressin)mDECREASED,mAtrialm
NatriureticmPeptidemINCREASED?mCm(block3,mq23)
Randomizedmcontrolledmstudymofm2000mpatientsmwithminsomniamismconductedmtomevaluatemthemef
ficacymofmamnewmmedicationmtomtreatmthismcondition.mTenmsubjectsmfrommbothmthemcontrolmandmtr
eatmentmgroupsmdomnotmcompletemthemstudymaremnotmincludedminmthemanalysis.mTreatmentmgrou
pmablemtomfallmasleepm5mminutesmfastermthanmcontrolm(p=0.001).mNeithermgroupmreportmanmimprov
ementminmqualitymofmlife.mConcludemthatmnewmmedmismefficaciousminmtreatingminsomnia.mTypemofme
