PMHNP EXAM PRACTICE QUESTIONS COMPLETE WITH 100% VERIFIED ANSWERS AND DETAILED EXPLANATIONS

PMHNP EXAM PRACTICE QUESTIONS COMPLETE QITH 100% VERIFIED ANSWERS AND DETAILED EXPLANATIONS 1. What is dissemination in research? A) Collecting data from study participants B) Getting research information out to those who need to know it C) Analyzing statistical results D) Designing the research methodology Correct Answer: B Explanation: Dissemination is the process of sharing research findings with those who can benefit from or apply the information. This includes publication (highest level), presenting at national and local conferences, and journal clubs where one person reviews an article. ________________________________________ 2. What does a score of 17 on the MMSE indicate? A) Normal cognitive function B) Mild cognitive impairment C) Moderate cognitive impairment D) Severe cognitive impairment Correct Answer: C Explanation: The Mini-Mental State Examination (MMSE) scoring: 25-30 = Normal, 21-24 = Mild/Early impairment, 10-21 = Moderate impairment, 0-9 = Severe impairment. A score of 17 falls in the moderate cognitive impairment range. ________________________________________ 3. How does Tegretol (carbamazepine) affect the CYP450 system? A) Inhibitor - will increase Lamictal levels B) Inducer - will lower dose of Lamictal and BCPs C) No effect on CYP450 system D) Substrate only Correct Answer: B Explanation: Tegretol (carbamazepine) is a CYP450 inducer, which means it speeds up the metabolism of other drugs, reducing their levels. This requires dose adjustments for medications like Lamictal and oral contraceptives. ________________________________________ 4. What effect do BCPs (birth control pills) have on Lamictal? A) Inhibitor - increases Lamictal levels B) No effect C) Inducer - will lower dose of Lamictal D) Both are substrates Correct Answer: C Explanation: Oral contraceptives are CYP450 inducers that lower Lamictal levels. When starting or stopping BCPs, Lamictal doses may need adjustment. ________________________________________ 5. What is a Type I research error? A) There is NO difference but you say there is a difference B) There IS a difference but you say there isn't a difference C) The study design is flawed D) The sample size is too small Correct Answer: B Explanation: A Type I error (false positive) occurs when you reject the null hypothesis when it is actually true - concluding there IS a difference when one does not exist. ________________________________________ 6. What is a Type II research error? A) There IS a difference but you say there isn't a difference B) There is NO difference but you say there is a difference C) The data collection method is invalid D) The statistical test is inappropriate Correct Answer: B Explanation: A Type II error (false negative) occurs when you fail to reject the null hypothesis when it is false - concluding there is NO difference when one actually exists. ________________________________________ 7. What is pseudo-dementia? A) Dementia that improves with treatment of depression B) Irreversible cognitive decline C) Normal age-related memory changes D) Early-stage Alzheimer's disease Correct Answer: A Explanation: Pseudo-dementia is cognitive impairment secondary to depression that resolves when the depression is treated, particularly in the elderly. True dementia will not improve. ________________________________________ 8. Is it normal for a 1-month-old to have a palmar grasp? A) No, this indicates a neurological problem B) Yes, this is a normal infantile reflex C) Only if the infant was born prematurely D) No, this should have disappeared by birth Correct Answer: B Explanation: The palmar grasp reflex is present at birth and typically lasts until about 5-6 months of age. Stroking the palm causes the infant to close their fingers in a grasp. ________________________________________ 9. What is a drug half-life? A) The time it takes for 100% of the drug to be eliminated B) The time it takes for 50% of the drug to be eliminated C) The time it takes for the drug to reach peak concentration D) The duration of therapeutic effect Correct Answer: B Explanation: Drug half-life is the time required for the concentration of a drug in the body to decrease by 50%. ________________________________________ 10. Which 3 atypical antipsychotics can be used with teens? A) Risperdal, Clozaril, Geodon B) Zyprexa, Abilify, Seroquel C) Haldol, Thorazine, Prolixin D) Latuda, Fanapt, Invega Correct Answer: B Explanation: Zyprexa (olanzapine), Abilify (aripiprazole), and Seroquel (quetiapine) can be used in adolescents at low doses. Other atypicals may not have sufficient safety data in this population. ________________________________________ 11. What is a risk of using Tramadol? A) Serotonin Syndrome B) Severe hypotension C) Liver failure D) Kidney damage Correct Answer: A Explanation: Tramadol is highly serotonergic and carries a significant risk of Serotonin Syndrome, especially when combined with other serotonergic agents like SSRIs, SNRIs, or MAOIs. ________________________________________ 12. What allele seen in Asians increases the risk of SJS (Stevens-Johnson Syndrome)? A) HLA-B27 B) HLA-DR4 C) HLA-B1502 D) HLA-Cw6 Correct Answer: C Explanation: The HLA-B*1502 allele is strongly associated with increased risk of Stevens-Johnson Syndrome and toxic epidermal necrolysis in Asian populations when taking carbamazepine and other AEDs. ________________________________________ 13. When might you see toxic epidermal necrolysis (TEN)? A) As a separate condition from SJS B) With worsening of SJS C) Only in pediatric patients D) Only with topical medications Correct Answer: B