r r r r r r r r r
ATE 2024/25
r
ANTI-GLAUCOMArDRUGSr-
rcorrectranswerrDrugsrThatrReducerIntraocularrPressurerByrLoweringrTherAmountrOfrAqueousrHumorrInrTh
erEyeball,rReducingrItsrProduction,rOrrIncreasingrItsrOutflow
OPHTHALMICrCATEGORIESr-rcorrectranswerrCholinergicrDrugsr(Miotics)
Sympathomimeticsr(Mydriatics)
Beta-AdrenergicrBlockers
CarbonicrAnnhydraserInhibitors
ProstaglandinrAgonists
LubricantsrandrMoisturizers
Aminoglycosides
MacroliderAntibiotics
PolypeptiderAntibiotics
QuinolonerAntibiotics
Sulfonamides
Corticosteroid
DiagnosticrDrugs=rCycloplegicrMydriatics
TYPESrOFrANTI-GLAUCOMArDRUGSr-rcorrectranswerrCHOLINERGICrDRUGS
SYMPATHOMIMETICS
BETA-ADRENERGICrBLOCKERS
CARBONICrANHYDRASErINHIBITORS
OSMOTICrDIURETICS
PROSTAGLANDINrAGONISTS
,CHOLINERGICrDRUGSr-
rcorrectranswerrTheserDrugsrArerMotifs.rTheyrArerAgentsrThatrStimulaterTherParasympatheticrNervousrSyst
emrInrTherSamerMannerrAsrAcetylcholine.
ThererArerDirectrActingrAndrIndirectrActingrDrugs.
INDIRECTrACTINGrMIOTICSr-rcorrectranswerrECHOTHIOPHATE
ECHOTHIOPHATEr-
rcorrectranswerrOrganophosphaterCholinesteraserInhibitor:rLessrLipidrSolublerThanrMostrOrganophosphat
es;rUsedrInrGlaucoma.rLongerrLastingr-r7rTor28rDays.
DIRECTrACTINGrMIOTICSr-rcorrectranswerrPILOCARPINE
CARBACHOL
ACETYLCHOLINE
ACETYLCHOLINE
PILOCARPINEr-rcorrectranswerrDirectrActingrCholinergicrDrug
Indication-PrimaryrOpenrAngledrAndrAcuterAnglerClosurerGlaucomarOrrOcularrHypertension
IncreasesrAqueousrHumorrDrainagerAndrDecreasesrIntra-OcularrPressure
Moa-MimicsrAcetylcholinerByrStimulatingrCholinergicrReceptors
DurationrOfrActionrPilocarpine=r4-8rHours
DurationrOfrActionrAcetylcholine=10rMin
SolutionrOrrGel
SYMPATHOMIMETICrDRUGSr-rcorrectranswerrMydriaticrDrug
UsedrForrTherTreatmentrOfrGlaucomarAndrOcularrHypertension.
TheyrMimicrTherSympatheticrNeurotransmittersrNoepinephrinerAndrEpinephrine.
TYPESrOFrSYMPATHOMIMETICrDRUGSr-rcorrectranswerrDIPIVEFRIN
APRACLONIDINE
, DIPIVEFRINr-rcorrectranswerrAKA:rPropine
APRACLONIDINEr-rcorrectranswerrAKA:rIopidine
BETA-ADRENERGICrBLOCKERSr-
rcorrectranswerrAnrOphthalmicrBetarBlockerrThatrReducesrBothrElevatedrAndrNormalrIntra-
OcularrPressure.rTheyrReducerIntra-OcularrPressurerByrReducingrAqueousrHumorrFormation.
TYPESrOFrBETA-ADRENERGICrBLOCKERSr-rcorrectranswerrBETAXOLOL
TIMOLOL
BETAXOLOLr-rcorrectranswerrAKA:rBetoptic
ChronicrOpen-AnglerGlaucoma,rOcularrHtn
OnerOfrTherMostrPotentrAndrSelectiverBetarBlockingrDrugs.
TIMOLOLr-rcorrectranswerrAKA:rTimoptic
ThisrBetarBlockerrIsrTherOnlyrOnerThatrMayrIncreaserTherOutflowrOfrAqueousrHumorrAsrWellrAsrDecreaserIt
srFormation.rThisrIsrAvailablerInrGelrAndrLiquidrForm.
CARBONICrANHYDRASErINHIBITORSr-
rcorrectranswerrTreatsrGlaucomarByrDecreasingrAqueousrHumorrProduction.r
OnlyrAvailablerInrTopicalrOphthalmicrForm.rTheserDrugsrWorkrByrInhibitingrTherEnzymerCarbonicrAnhydras
e,rWhichrResultsrInrDecreasedrIntra-
OcularrPressurerByrReducingrAqueousrHumorrFormation.rPrimarilyrUsedrForrGlaucoma.
TYPESrOFrCARBONICrANHYDRASErINHIBITORrDRUGSr-rcorrectranswerrBRINZOLAMIDE
DORZOLAMIDE
BRINZOLAMIDEr-rcorrectranswerrAKA:rAzopt