Summary NSG 6005 Week 2 Quiz / NSG6005 Week 2 Quiz (Latest 2022/2023): South University 1. Question 1: Question A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to prescribing because: Distribution of drugs to target tissue ma

NSG 6005 Week 2 Quiz / NSG6005 Week 2 Quiz (Latest 2022/2023): South University 1. Question 1: Question A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to prescribing because: Distribution of drugs to target tissue may be affected The solubility of the drug will not match the site of absorption There will be less free drug available to generate an effect Drugs bound to albumin are readily excreted by the kidney Question 2. Question : The first step in the prescribing process according to the World Health Organization is: Choosing the treatment Educating the patient about the medication Diagnosing the patient’s problem Starting the treatment Question 3. Question : Which of the following factors may adversely affect a patient’s adherence to a therapeutic drug regimen? Complexity of the drug regimen Patient’s perception of the potential adverse effects of the drugs Both A and B Neither A nor B Question 4. Question : Which one of the following statements about bioavailability is true? Bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained release mechanisms. All brands of a drug have the same bioavailability. Drugs that are administered more than once a day have greater bioavailability than drugs given once daily. Combining an active drug with an inert substance does not affect bioavailability. Question 5. Question : Drugs that have a significant first-pass effect: Must be given by the enteral (oral) route only Bypass the hepatic circulation Are rapidly metabolized by the liver and may have little if any desired action Are converted by the liver to more active and fat-soluble forms Question 6. Question : Carbamazepine has a black box warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to: Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine 0 of 2.5 Question 7. Question : The major reason for not crushing a sustained release capsule is that, if crushed, the coated beads of the drugs could possibly result in: Disintegration Toxicity Malabsorption Deterioration Question 8. Question : The role of the nurse practitioner in the use of herbal medication is to: Maintain competence in the prescribing of common herbal remedies. Recommend common OTC herbs to patients. Educate patients and guide them to appropriate sources of care. Encourage patients to not use herbal therapy due to the documented dangers. Question 9. Question : The time required for the amount of drug in the body to decrease by 50% is called: Steady state Half-life Phase II metabolism Reduced bioavailability time Question 10. Question : The angiotensin converting enzyme (ACE) inhibitor lisinopril is a known teratogen. Teratogens cause Type ____ ADR. A B C D Question 11. Question : Genetic polymorphisms account for differences in metabolism, including: Poor metabolizers (PMs) that lack a working enzyme Intermediate metabolizers (IMs) that have one working, wild-type allele and one mutant allele Extensive metabolizers (EMs), with two normally functioning alleles All of the above Question 12. Question : Pharmacokinetic factors that affect prescribing include: Therapeutic index Minimum effective concentration Bioavailability Ease of titration Question 13. Question : Warfarin resistance may be seen in patients with VCORC1 mutation, leading to: Toxic levels of warfarin building up Decreased response to warfarin Increased risk for significant drug interactions with warfarin Less risk of drug interactions with warfarin Question 14. Question : Patient education regarding prescribed medication includes: Instructions written at the high school reading level Discussion of expected ADRs How to store leftover medication such as antibiotics Verbal instructions always in English Question 15. Question : The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the: Minimum adverse effect level Peak of action Onset of action Therapeutic range Question 16. Question : Herbs and supplements are tested for safety by the FDA. True False Question 17. Question : The elderly are at high risk of ADRs due to: Having greater muscle mass than younger adults, leading to higher volume of distribution The extensive studies that have been conducted on drug safety in this age group The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect Age-related decrease in renal function Question 18. Question : Common OTC pain relievers such as acetaminophen or ibuprofen: Are always safer for the patient than prescription pain medication Are harmful if taken in higher-than-recommended amounts Have minimal interaction with prescription medications Should never be given to children unless recommended by their provider