Maryville University Pharmacology NURS615 Pharm
Exam 3
1. UPDATED ACTUAL QUESTIONS AND CORRECT Answers What hormones are pro-
Corticosteroids/glucocorticoids/steroids
duced by the adrenal gland
and maintain homeostasis?
2. Cortisol What is an endogenous
glucocorticoid?
3. 1. Glucocorticoids What are the 3 categories
2. Mineralcorticoids of steroid hormones?
3. Adrenal Sex Hormones
4. 1. Inhibits the immune and inflammatory system What is the MOA of corti-
2. Inhibits arachidonic acid metabolism costeroids?
3. Inhibits production of ILK-1, TNF, and other cy-
tokines
4. Impairs lymphocytes and inhibits tissue repair
5. hydrocortisone, prednisone, methyprednisolone, Examples of glucocorticoid
dexamethasone medications
6. Life-threatening conditions or severe disabling symp- What is long-term glu-
toms cocorticoid use indicated
for?
7. Self-limiting conditions What is short-term glu-
cocorticoid use indicated
for?
8. 1. Osteoporosis What are the adverse ef-
2. Worsens diabetic control and increases blood glu- fects of glucocorticoids af-
cose (diabetics need more insulin) ter 6 months of use?
3. Promotes gastric secretion and causes abdominal
pain, N/V (Report black tarry stools)
, Maryville University Pharmacology NURS615 Pharm
Exam 3
9. UPDATED
Within ACTUAL
the first QUESTIONS AND CORRECT Answers When does bone density
3 months
begin to decline because of
a decrease in calcium from
glucocorticosteroid use?
10. 1. Retains sodium and water General adverse effects of
2. Increases appetite glucocorticosteroids
3. Promotes fat deposit in cervical area and face
4. Increases uric acid
5. Delerium, insomnia, mood alterations, anxiety
6. Adrenal suppression
7. Poor wound healing, thin skin, acne, ocular dam-
age
11. 1. To avoid recurrent activity of underlying disease Why must glucocorticos-
2. To avoid possible cortisol deficiency resulting from teroids be tapered?
the HPA axis and HPA suppression during steroid
therapy
12. 1. Administer for short courses and then taper; do How should glucocorticos-
NOT abruptly withdrawal teroids be discontinued?
13. In the morning When is the ideal time to
administer prednisone?
14. 1. Severe infections When are glucocorticos-
2. Allergy teroids contraindicated?
15. 1. Low carb, low sodium, and high protein diet What is patient education
2. Increase calcium and vitamin D for glucocorticosteroid use?
3. Monitor weight, edema, blood glucose, blood pres-
sure, potassium, electrolytes, and CBC
, Maryville University Pharmacology NURS615 Pharm
Exam 3
16. Decreases
UPDATED inflammation by decreasing
ACTUAL QUESTIONS the move-
AND CORRECT Answers What is the MOA of
ment of leukocytes into tissues containing urate crys- colchicine?
tals -- this affects the way the body responds to the
uric acid -- DECREASES swelling and pain
17. Prophylaxis of gout flares in adults (or to treat Be- What is the indication of
hcets syndrome) colchicine?
18. Not a cure and does not prevent the disease from Is colchicine curative?
progressing
19. 1.2mg followed by 0.6mg 1 hr later (for 1.8mg total) What is low-dose
colchicine?
20. 1.2mg followed by 0.6mg every 4-6hours (for 4.8mg What is high-dose
total) colchicine?
21. Low-dose is AS EFFECTIVE as high-dose with LESS side Is high or low-dose
effects colchicine preferred?
22. DIARRHEA (make sure this is in patient teaching) What is the main side effect
of colchicine?
23. Prevents formation of uric acid by inhibiting xanthine What is the MOA of allop-
oxidase urinol (Zyloprim)?
24. Taken DAILY to prevent formation of uric acid crystals How often is allopurinol
(Zyloprim) taken?
25. Gout may worsen initially with therapy What is important pa-
tient teaching for febuxo-
stat (Uloric)?
26. Patients should be treated with NSAIDs concurrently
Exam 3
1. UPDATED ACTUAL QUESTIONS AND CORRECT Answers What hormones are pro-
Corticosteroids/glucocorticoids/steroids
duced by the adrenal gland
and maintain homeostasis?
2. Cortisol What is an endogenous
glucocorticoid?
3. 1. Glucocorticoids What are the 3 categories
2. Mineralcorticoids of steroid hormones?
3. Adrenal Sex Hormones
4. 1. Inhibits the immune and inflammatory system What is the MOA of corti-
2. Inhibits arachidonic acid metabolism costeroids?
3. Inhibits production of ILK-1, TNF, and other cy-
tokines
4. Impairs lymphocytes and inhibits tissue repair
5. hydrocortisone, prednisone, methyprednisolone, Examples of glucocorticoid
dexamethasone medications
6. Life-threatening conditions or severe disabling symp- What is long-term glu-
toms cocorticoid use indicated
for?
7. Self-limiting conditions What is short-term glu-
cocorticoid use indicated
for?
8. 1. Osteoporosis What are the adverse ef-
2. Worsens diabetic control and increases blood glu- fects of glucocorticoids af-
cose (diabetics need more insulin) ter 6 months of use?
3. Promotes gastric secretion and causes abdominal
pain, N/V (Report black tarry stools)
, Maryville University Pharmacology NURS615 Pharm
Exam 3
9. UPDATED
Within ACTUAL
the first QUESTIONS AND CORRECT Answers When does bone density
3 months
begin to decline because of
a decrease in calcium from
glucocorticosteroid use?
10. 1. Retains sodium and water General adverse effects of
2. Increases appetite glucocorticosteroids
3. Promotes fat deposit in cervical area and face
4. Increases uric acid
5. Delerium, insomnia, mood alterations, anxiety
6. Adrenal suppression
7. Poor wound healing, thin skin, acne, ocular dam-
age
11. 1. To avoid recurrent activity of underlying disease Why must glucocorticos-
2. To avoid possible cortisol deficiency resulting from teroids be tapered?
the HPA axis and HPA suppression during steroid
therapy
12. 1. Administer for short courses and then taper; do How should glucocorticos-
NOT abruptly withdrawal teroids be discontinued?
13. In the morning When is the ideal time to
administer prednisone?
14. 1. Severe infections When are glucocorticos-
2. Allergy teroids contraindicated?
15. 1. Low carb, low sodium, and high protein diet What is patient education
2. Increase calcium and vitamin D for glucocorticosteroid use?
3. Monitor weight, edema, blood glucose, blood pres-
sure, potassium, electrolytes, and CBC
, Maryville University Pharmacology NURS615 Pharm
Exam 3
16. Decreases
UPDATED inflammation by decreasing
ACTUAL QUESTIONS the move-
AND CORRECT Answers What is the MOA of
ment of leukocytes into tissues containing urate crys- colchicine?
tals -- this affects the way the body responds to the
uric acid -- DECREASES swelling and pain
17. Prophylaxis of gout flares in adults (or to treat Be- What is the indication of
hcets syndrome) colchicine?
18. Not a cure and does not prevent the disease from Is colchicine curative?
progressing
19. 1.2mg followed by 0.6mg 1 hr later (for 1.8mg total) What is low-dose
colchicine?
20. 1.2mg followed by 0.6mg every 4-6hours (for 4.8mg What is high-dose
total) colchicine?
21. Low-dose is AS EFFECTIVE as high-dose with LESS side Is high or low-dose
effects colchicine preferred?
22. DIARRHEA (make sure this is in patient teaching) What is the main side effect
of colchicine?
23. Prevents formation of uric acid by inhibiting xanthine What is the MOA of allop-
oxidase urinol (Zyloprim)?
24. Taken DAILY to prevent formation of uric acid crystals How often is allopurinol
(Zyloprim) taken?
25. Gout may worsen initially with therapy What is important pa-
tient teaching for febuxo-
stat (Uloric)?
26. Patients should be treated with NSAIDs concurrently
