NR507 Midterm Exam 2025: Advanced Pathophysiology Practice Questions & Study Guide

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MIDTERM EXAM: NR507 / NR-507 (LATEST UPDATE

STUDY BUNDLE WITH COMPLETE

SOLUTIONS) ADVANCED PATHOPHYSIOLOGY |

QUESTIONS & VERIFIED ANSWERS | 100% CORRECT |

GRADE A - CHAMBERLAIN

Hypersensitivity: Type 1 .....ANSWER.....-Mediated IgE

-inflammation due to mast cell degranultion

-anaphylactic, asthma, hay fever

treatment: epinephrine

Hypersensitivity: Type 2 .....ANSWER.....-Cytotoxic reaction: tissue

specific

-binds to the antigen ON THE CELL SURFACE

-macrophages are primary effectors cells involved

cause tissue damage or alter function

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Hypersensitivity 2 .....ANSWER.....-Graves Disease

(hyperthyroidism) -alters function not destroy

-blood transfusions reaction- transfused erythrocytes are

destroyed by agglutination or lysis

-drug allergies

-hemolytic anemia

Hypersensitivity: type 3 .....ANSWER.....-Not organ specific

-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE

that was released into the blood or bodily fluids, and the

complex is then deposited in the tissues

Hypersensitivity: Type 3 .....ANSWER.....-rheumatoid arthritis

-Systemic Lupus Erythematosus (SLE)

-Raynaud's

Hives (urticaria) .....ANSWER.....Hypersensitivity Type 1

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First responders to innate the immune system

.....ANSWER.....Neutrophils

Allergic contact dermatitis .....ANSWER.....Hypersensitivity Type

IV

Type 2 cytotoxic hypersensitivity mediated by: .....ANSWER.....-

IgG IgM

-macrophages are primary effort cells

-

Serum Sickness .....ANSWER.....type 3 hypersensitivity

Hypersensitivity IV, .....ANSWER.....-is more of a delayed immune

response.

-mediated T-cells attack tissue directly (no antibodies)

Autoimmune .....ANSWER.....-diseases in which the body makes

antibodies directed against its own tissues

-

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Primary immunodeficiency .....ANSWER.....-Genetic; inherited

-result of single gene defects

-B and T cell deficiencies

secondary immunodeficiency .....ANSWER.....-acquired

Common cause of secondary immunodeficiency

.....ANSWER.....Malnutrition

Most patients diagnosed with SLE will have a positive ?

.....ANSWER.....antinuclear antibody (ANA)

SLE (lupus) .....ANSWER.....-Facial rash

-vasculitis

- tissue inflammation

Renal disease associated with autoimmunity?

.....ANSWER.....Glomerulonephritis