Lehninger Principles of Biochemistry
David L. Nelson
Seventh Edition
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,Contents — Lehninger Principles of Biochemistry (7th Edition)
1. The Foundations of Biochemistry
Part I — Structure and Catalysis
2. Water
3. Amino Acids, Peptides, and Proteins
4. The Three-Dimensional Structure of Proteins
5. Protein Function
6. Enzymes
7. Carbohydrates and Glycobiology
8. Nucleotides and Nucleic Acids
9. DNA-Based Information Technologies
10. Lipids
11. Biological Membranes and Transport
12. Biosignaling
Part II — Bioenergetics and Metabolism
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13. Bioenergetics and Biochemical Reaction Types
14. Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
15. Principles of Metabolic Regulation
16. The Citric Acid Cycle
17. Fatty Acid Catabolism
18. Amino Acid Oxidation and the Production of Urea
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19. Oxidative Phosphorylation
20. Photosynthesis and Carbohydrate Synthesis in Plants
21. Lipid Biosynthesis
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22. Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
23. Hormonal Regulation and Integration of Mammalian Metabolism
Part III — Information Pathways
24. Genes and Chromosomes
25. DNA Metabolism
26. RNA Metabolism
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27. Protein Metabolism
28. Regulation of Gene Expression
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,1. In a bacterial cell, the DNA is in the:
A) cell envelope.
B) cell membrane.
C) nucleoid.
D) nucleus.
E) ribosomes.
2. A major change occurring in the evolution of eukaryotes from prokaryotes was the
development of:
A) DNA.
B) photosynthetic capability.
C) plasma membranes.
D) ribosomes.
E) the nucleus.
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3. In eukaryotes, the nucleus is enclosed by a double membrane called the:
A) cell membrane.
B) nuclear envelope.
C) nucleolus.
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D) nucleoplasm.
E) nucleosome.
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4. The dimensions of living cells are limited, on the lower end by the minimum number of
biomolecules necessary for function, and on the upper end by the rate of diffusion of
solutes such as oxygen. Except for highly elongated cells, they usually have lengths and
diameters in the range of:
A) 0.1 m to 10 m.
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B) 0.3 m to 30 m.
C) 0.3 m to 100 m.
D) 1 m to 100 m.
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E) 1 m to 300 m.
5. Which group of single-celled microorganisms has many members found growing in
extreme environments?
A) bacteria
B) archaea
C) eukaryotes
D) heterotrophs
E) None of the answers is correct.
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, 6. The bacterium E. coli requires simple organic molecules for growth and energy—it is
therefore a:
A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) photoautotroph.
E) photoheterotroph.
7. Which is a list of organelles?
A) mitochondria, chromatin, endoplasmic reticulum
B) peroxisomes, lysosomes, plasma membrane
C) proteasomes, peroxisomes, lysosomes
D) mitochondria, endoplasmic reticulum, peroxisomes
E) All of the answers are correct.
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8. Which list has the cellular components arranged in order of INCREASING size?
A) amino acid < protein < mitochondrion < ribosome
B) amino acid < protein < ribosome < mitochondrion
C) amino acid < ribosome < protein < mitochondrion
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D) protein < amino acid < mitochondrion < ribosome
E) protein < ribosome < mitochondrion < amino acid
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9. The three-dimensional structure of macromolecules is formed and maintained primarily
through noncovalent interactions. Which one of the following is NOT considered a
noncovalent interaction?
A) carbon-carbon bonds
B) hydrogen bonds
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C) hydrophobic interactions
D) ionic interactions
E) van der Waals interactions
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10. Which element is NOT among the four most abundant in living organisms?
A) carbon
B) hydrogen
C) nitrogen
D) oxygen
E) phosphorus
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