TEST BANK
.
Genetics and Genomics in Nursing and Health Care
. . . . . . .
by Theresa A. Beery, M. Linda Workman
. . . . . .
Second Edition
.
FULL TEST BANK!!!
. .
, Chapter 1: DNAStructure and Function
. . . . .
Multiple.Choice
Identify.the.choice.that.best.completes.the.statement.or.answers.the.question.
. . A. 1.. In.which.body.or.cell.area.are.most.genes.in.humans.located?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma.membrane
. . A. 2.. Which.condition.or.statement.exemplifies.the.concept.of.genomics.rather.than.genetics?
A. The.gene.for.insulin.is.located.on.chromosome.11.in.all.people.
B. Expression.of.any.single.gene.is.dependent.on.inheriting.two.alleles.
C. Sex-linked.recessive.disorders.affect.males.more.often.than.females.
D. One.allele.for.each.gene.is.inherited.from.the.mother,.and.one.is.inherited.from.the.father
.
. . A. 3.. What.is.the.purpose.of.phosphorous.in.a.DNA.strand?
A. Linking.the.nucleotides.into.a.strand
B. Holding.complementary.strands.together
C. Ensuring.that.a.purine.is.always.paired.with.a.pyrimidine
D. Preventing.the.separation.of.double-stranded.DNA.into.single-stranded.DNA
. A.
4..What.is.the.term.used.to.define.alternative.forms.of.a.gene.that.may.result.in.different.expre
ssion.of.the.trait.coded.for.by.that.gene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
. D. 5..What.percentage.of.bases.in.a.stretch.of.double-
stranded.DNA.that.contains.30%.guanine.(G).bases.would.be.adenine.(A)?
A. 70%
B. 60%
C. 30%
D. 20%
. C.
6..What.is.the.term.used.to.describe.the.organized.picture.of.the.paired.chromosomes.within.
a.cell.used.to.determine.whether.chromosome.numbers,.structures,.and.banding.patterns.are.normal
?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
. D.
7..What.would.be.the.sequence.of.DNA.that.is.complementary.to.a.DNA.section.with.th
e.base.sequence.of.GGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
,. . B. 8.. Which.of.these.complementary.base.pairs.form.the.strongest.or.“tightest”.association?
A. Adenine.and.thymine
B. Cytosine.and.guanine
C. Guanine.and.thymine
D. Cytosine.and.adenine
. . A 9.. What.activity.occurs.during.M.phase.of.the.cell.cycle?
A. The.cell.undergoes.cytokinesis.
B. Activity.stops,.and.the.cell.“sleeps.”
C. All.DNA.is.completely.replicated.
D. The.cell.greatly.increases.protein.synthesis.
. . B.. . 10.. Which.chromosome.number.represents.the.euploid.state.for.normal.human.somatic.cells?
A. 44
B. 46
C. 47
D. 48
. . A.. 11.. How.does.the.proteome.differ.from.the.genome?
A. The.proteome.changes.in.response.to.intracellular.and.extracellular.signals.
B. The.genome.changes.in.response.to.intracellular.and.extracellular.signals.
C. The.proteome.is.stable.in.somatic.cells.and.unstable.in.germ.cells,.whereas.the.geno
me.is.stable.in.both.somatic.cells.and.germ.cells.
D. The.genome.is.stable.in.somatic.cells.and.unstable.in.germ.cells,.whereas.the.prot
eome.is.stable.in.both.somatic.cells.and.germ.cells.
. . C.. . 12.. What.is.the.most.outstanding.feature.of.a.mature.haploid.cell?
A. It.is.usually.homozygous.
B. The.sex.chromosomes.are.missing.
C. Only.one.chromosome.of.each.pair.is.present.
D. DNA.synthesis.occurs.after.mitosis.instead.of.before.
. . D.. . 13.. At.what.phase.of.the.cell.cycle.are.chromosomes.visible.as.separate.structures?
A. G1
B. G2
C. S
D. M
. . B.. 14.. Which.statement.about.the.cell.cycle.phase.of.G0. is.true?
A. Hyperplastic.growth.in.place.of.hypertrophic.growth
B. Performance.of.specific.differentiated.functions
C. Initiation.and.completion.of.nucleokinesis
D. Replication.of.DNA
. . B.. 15.. What.is.the.result.of.normal.DNA.replication?
A. Formation.of.two.new.daughter.cells
B. Formation.of.two.identical.sets.of.DNA
C. Disappearance.of.the.original.parent.cell
D. Activation.and.attachment.of.spindle.fibers
, . . A.. 16.. Which.statement.regarding.chromosome.structure.or.function.is.true?
A. The.chromatids.of.any.single.chromosome.are.known.as.“sister.chromatids.”
B. The.genes.located.on.the.telomeres.of.chromosomes.are.identical.to.the.genes.in.the.c
entromeres.
C. Immediately.before.the.mitosis.phase.of.cell.division,.the.chromosomes.of.all.som
atic.cells.are.haploid.
D. A.specific.gene.allele.on.one.chromosome.has.a.complementary.allele.on.the.other.chro
mosome.of.a.pair.
. . C.. . 17.. Why.does.a.person.with.normal.chromosomes.only.have.two.alleles.for.any.single.gene.trait?
A. A.minimum.of.two.alleles.is.required.for.the.expression.of.monogenic.traits.
B. When.a.dominant.allele.is.paired.with.a.recessive.allele,.only.the.dominant.allele.is.expr
essed,.and.the.recessive.allele.is.silent.
C. One.allele.for.the.monogenic.trait.is.on.the.paternally.derived.chromosome,.and.the.
other.allele.is.on.the.maternally.derived.chromosome.
D. Expression.of.more.than.two.alleles.of.any.single-
gene.trait.results.in.enhanced.expression.of.recessive.alleles.and.suppressed.expres
sion.of.dominant.alleles.
. . C 18.. Under.what.normal.condition.are.genotype.and.phenotype.always.the.same?
A. Euploidy.of.alleles
B. Aneuploidy.of.alleles
C. Homozygosity.of.alleles
D. Heterozygosity.of.alleles
.. D.. 19.. What.would.be.the.expected.result.of.a.drug.that.affected.a.particular.tissue.by.causing.new.DNA.to.fo
rm.with.covalent.bonds.instead.of.hydrogen.bonds?
A. None.of.the.cells.in.the.affected.tissue.would.be.able.to.leave.G0. and.enter.the.cell.cycle.
B. Replication.of.DNA.would.result.in.identical.DNA.strands.instead.of.co
mplementary.strands.
C. Mitosis.of.cells.in.the.tissue.would.result.in.the.production.of.three.new.daughter.cells.
instead.of.just.two.
D. The.new.cells.that.formed.within.this.tissue.would.not.be.able.to.complete.the.next.roun
d.of.mitosis.successfully.
. . B.. 20.. How.does.the.DNA.enzyme.topoisomerase.contribute.to.DNA.replication?
A. Unwinds.the.double.helix.and.separates.the.double-stranded.DNA
B. Creates.a.“nick”.in.the.DNA.supercoils,.allowing.them.to.straighten.before.repl
ication
C. Initiates.DNA.synthesis.in.multiple.sites.down.the.strand,.making.the.process.more.effic
ient
D. Connects.and.links.the.individual.pieces.of.newly.synthesized.DNA.to.form.a.sing
le.strand
. . A.. 21.. Where.is.telomeric.DNA.located?
A. At.the.tips.of.the.p.and.q.arms.of.chromosomes.
B. In.the.mitochondria.of.all.somatic.cells
C. Only.in.the.germ.cells.(ova.and.sperm)
D. Within.the.histones.of.the.solenoid
.
Genetics and Genomics in Nursing and Health Care
. . . . . . .
by Theresa A. Beery, M. Linda Workman
. . . . . .
Second Edition
.
FULL TEST BANK!!!
. .
, Chapter 1: DNAStructure and Function
. . . . .
Multiple.Choice
Identify.the.choice.that.best.completes.the.statement.or.answers.the.question.
. . A. 1.. In.which.body.or.cell.area.are.most.genes.in.humans.located?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma.membrane
. . A. 2.. Which.condition.or.statement.exemplifies.the.concept.of.genomics.rather.than.genetics?
A. The.gene.for.insulin.is.located.on.chromosome.11.in.all.people.
B. Expression.of.any.single.gene.is.dependent.on.inheriting.two.alleles.
C. Sex-linked.recessive.disorders.affect.males.more.often.than.females.
D. One.allele.for.each.gene.is.inherited.from.the.mother,.and.one.is.inherited.from.the.father
.
. . A. 3.. What.is.the.purpose.of.phosphorous.in.a.DNA.strand?
A. Linking.the.nucleotides.into.a.strand
B. Holding.complementary.strands.together
C. Ensuring.that.a.purine.is.always.paired.with.a.pyrimidine
D. Preventing.the.separation.of.double-stranded.DNA.into.single-stranded.DNA
. A.
4..What.is.the.term.used.to.define.alternative.forms.of.a.gene.that.may.result.in.different.expre
ssion.of.the.trait.coded.for.by.that.gene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
. D. 5..What.percentage.of.bases.in.a.stretch.of.double-
stranded.DNA.that.contains.30%.guanine.(G).bases.would.be.adenine.(A)?
A. 70%
B. 60%
C. 30%
D. 20%
. C.
6..What.is.the.term.used.to.describe.the.organized.picture.of.the.paired.chromosomes.within.
a.cell.used.to.determine.whether.chromosome.numbers,.structures,.and.banding.patterns.are.normal
?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
. D.
7..What.would.be.the.sequence.of.DNA.that.is.complementary.to.a.DNA.section.with.th
e.base.sequence.of.GGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
,. . B. 8.. Which.of.these.complementary.base.pairs.form.the.strongest.or.“tightest”.association?
A. Adenine.and.thymine
B. Cytosine.and.guanine
C. Guanine.and.thymine
D. Cytosine.and.adenine
. . A 9.. What.activity.occurs.during.M.phase.of.the.cell.cycle?
A. The.cell.undergoes.cytokinesis.
B. Activity.stops,.and.the.cell.“sleeps.”
C. All.DNA.is.completely.replicated.
D. The.cell.greatly.increases.protein.synthesis.
. . B.. . 10.. Which.chromosome.number.represents.the.euploid.state.for.normal.human.somatic.cells?
A. 44
B. 46
C. 47
D. 48
. . A.. 11.. How.does.the.proteome.differ.from.the.genome?
A. The.proteome.changes.in.response.to.intracellular.and.extracellular.signals.
B. The.genome.changes.in.response.to.intracellular.and.extracellular.signals.
C. The.proteome.is.stable.in.somatic.cells.and.unstable.in.germ.cells,.whereas.the.geno
me.is.stable.in.both.somatic.cells.and.germ.cells.
D. The.genome.is.stable.in.somatic.cells.and.unstable.in.germ.cells,.whereas.the.prot
eome.is.stable.in.both.somatic.cells.and.germ.cells.
. . C.. . 12.. What.is.the.most.outstanding.feature.of.a.mature.haploid.cell?
A. It.is.usually.homozygous.
B. The.sex.chromosomes.are.missing.
C. Only.one.chromosome.of.each.pair.is.present.
D. DNA.synthesis.occurs.after.mitosis.instead.of.before.
. . D.. . 13.. At.what.phase.of.the.cell.cycle.are.chromosomes.visible.as.separate.structures?
A. G1
B. G2
C. S
D. M
. . B.. 14.. Which.statement.about.the.cell.cycle.phase.of.G0. is.true?
A. Hyperplastic.growth.in.place.of.hypertrophic.growth
B. Performance.of.specific.differentiated.functions
C. Initiation.and.completion.of.nucleokinesis
D. Replication.of.DNA
. . B.. 15.. What.is.the.result.of.normal.DNA.replication?
A. Formation.of.two.new.daughter.cells
B. Formation.of.two.identical.sets.of.DNA
C. Disappearance.of.the.original.parent.cell
D. Activation.and.attachment.of.spindle.fibers
, . . A.. 16.. Which.statement.regarding.chromosome.structure.or.function.is.true?
A. The.chromatids.of.any.single.chromosome.are.known.as.“sister.chromatids.”
B. The.genes.located.on.the.telomeres.of.chromosomes.are.identical.to.the.genes.in.the.c
entromeres.
C. Immediately.before.the.mitosis.phase.of.cell.division,.the.chromosomes.of.all.som
atic.cells.are.haploid.
D. A.specific.gene.allele.on.one.chromosome.has.a.complementary.allele.on.the.other.chro
mosome.of.a.pair.
. . C.. . 17.. Why.does.a.person.with.normal.chromosomes.only.have.two.alleles.for.any.single.gene.trait?
A. A.minimum.of.two.alleles.is.required.for.the.expression.of.monogenic.traits.
B. When.a.dominant.allele.is.paired.with.a.recessive.allele,.only.the.dominant.allele.is.expr
essed,.and.the.recessive.allele.is.silent.
C. One.allele.for.the.monogenic.trait.is.on.the.paternally.derived.chromosome,.and.the.
other.allele.is.on.the.maternally.derived.chromosome.
D. Expression.of.more.than.two.alleles.of.any.single-
gene.trait.results.in.enhanced.expression.of.recessive.alleles.and.suppressed.expres
sion.of.dominant.alleles.
. . C 18.. Under.what.normal.condition.are.genotype.and.phenotype.always.the.same?
A. Euploidy.of.alleles
B. Aneuploidy.of.alleles
C. Homozygosity.of.alleles
D. Heterozygosity.of.alleles
.. D.. 19.. What.would.be.the.expected.result.of.a.drug.that.affected.a.particular.tissue.by.causing.new.DNA.to.fo
rm.with.covalent.bonds.instead.of.hydrogen.bonds?
A. None.of.the.cells.in.the.affected.tissue.would.be.able.to.leave.G0. and.enter.the.cell.cycle.
B. Replication.of.DNA.would.result.in.identical.DNA.strands.instead.of.co
mplementary.strands.
C. Mitosis.of.cells.in.the.tissue.would.result.in.the.production.of.three.new.daughter.cells.
instead.of.just.two.
D. The.new.cells.that.formed.within.this.tissue.would.not.be.able.to.complete.the.next.roun
d.of.mitosis.successfully.
. . B.. 20.. How.does.the.DNA.enzyme.topoisomerase.contribute.to.DNA.replication?
A. Unwinds.the.double.helix.and.separates.the.double-stranded.DNA
B. Creates.a.“nick”.in.the.DNA.supercoils,.allowing.them.to.straighten.before.repl
ication
C. Initiates.DNA.synthesis.in.multiple.sites.down.the.strand,.making.the.process.more.effic
ient
D. Connects.and.links.the.individual.pieces.of.newly.synthesized.DNA.to.form.a.sing
le.strand
. . A.. 21.. Where.is.telomeric.DNA.located?
A. At.the.tips.of.the.p.and.q.arms.of.chromosomes.
B. In.the.mitochondria.of.all.somatic.cells
C. Only.in.the.germ.cells.(ova.and.sperm)
D. Within.the.histones.of.the.solenoid
