1|Page
NSG 6005 WEEK 2 Pharmacology Questions and Answers
with Solutions UPDATED!!!
Carbamazepine has a black box warning recommending testing
for the HLA-B*1502 allele in patients with Asian ancestry prior
to starting therapy due to:
A. Decreased effectiveness of carbamazepine in treating
seizures in Asian patients with the HLA-B*1502 allele
B. Increased risk for drug interactions in Asian patients with the
HLA-B*1502 allele
C. Increased risk for Stevens-Johnson syndrome in Asian
patients with HLA-B*1502 allele
D. Patients who have the HLA-B*1502 allele being more likely to
have a resistance to carbamazepine - ANSWER C. Increased risk
for Stevens-Johnson syndrome in Asian patients with HLA-
B*1502 allele
The elderly are at high risk of ADRs due to:
A. Having greater muscle mass than younger adults, leading to
higher volume of distribution
B. The extensive studies that have been conducted on drug
safety in this age group
, 2|Page
C. The blood-brain barrier being less permeable, requiring
higher doses to achieve therapeutic effect
D. Age related decrease in renal function - ANSWER D. Age
related decrease in renal function
Factors that affect gastric drug absorption include:
A. Liver enzyme activity
B. Protein-binding properties of the drug molecule
C. Lipid solubility of the drug
D. Ability to chew and swallow - ANSWER C. Lipid solubility of a
drug
A twenty-four-year-old male received multiple fractures in a
motor vehicle accident that required significant amounts of
opioid medication to treat his pain. He is at risk for Type __ ADR
when he no longer requires the opioids. - ANSWER E
A patient's nutritional intake and lab work reflect
hypoalbuminemia. This is critical to prescribing because: A.
Distribution of drugs to target tissue may be affected
NSG 6005 WEEK 2 Pharmacology Questions and Answers
with Solutions UPDATED!!!
Carbamazepine has a black box warning recommending testing
for the HLA-B*1502 allele in patients with Asian ancestry prior
to starting therapy due to:
A. Decreased effectiveness of carbamazepine in treating
seizures in Asian patients with the HLA-B*1502 allele
B. Increased risk for drug interactions in Asian patients with the
HLA-B*1502 allele
C. Increased risk for Stevens-Johnson syndrome in Asian
patients with HLA-B*1502 allele
D. Patients who have the HLA-B*1502 allele being more likely to
have a resistance to carbamazepine - ANSWER C. Increased risk
for Stevens-Johnson syndrome in Asian patients with HLA-
B*1502 allele
The elderly are at high risk of ADRs due to:
A. Having greater muscle mass than younger adults, leading to
higher volume of distribution
B. The extensive studies that have been conducted on drug
safety in this age group
, 2|Page
C. The blood-brain barrier being less permeable, requiring
higher doses to achieve therapeutic effect
D. Age related decrease in renal function - ANSWER D. Age
related decrease in renal function
Factors that affect gastric drug absorption include:
A. Liver enzyme activity
B. Protein-binding properties of the drug molecule
C. Lipid solubility of the drug
D. Ability to chew and swallow - ANSWER C. Lipid solubility of a
drug
A twenty-four-year-old male received multiple fractures in a
motor vehicle accident that required significant amounts of
opioid medication to treat his pain. He is at risk for Type __ ADR
when he no longer requires the opioids. - ANSWER E
A patient's nutritional intake and lab work reflect
hypoalbuminemia. This is critical to prescribing because: A.
Distribution of drugs to target tissue may be affected
