Congenital Anomalies & Birth Defects;
Practice Quiz Questions and Answers
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Leading cause of infant mortality Ans: birth defects
Birth defects can be classified into what 5 categories? Ans:
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Structural, Functional, Metabolic, Behavioral, Hereditary
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How many children worldwide have a serious birth defect?
Ans: 8 million
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Neural tube defect is an example of which type of birth defect?
Ans: congenital abnormaility
Fetal toxoplasmosis is an example of which type of birth
defect? Ans: fetal disease
Cystic fibrosis is an example of which type of birth defect?
Ans: Genetic disease
Autism is an example of which type of birth defect? Ans:
Mental disorders
Principles of embryology, pathology and toxicology to
understand & classify developmental defects of malformed
embryos and fetuses Ans: Teratology
Effect of teratogens depend on: Ans: - Critical periods of
development
, 2
- Dose of the drug or chemical
- Genetic background of the embryo
The medical belief that baby's are protected in the womb by
sterile environment changed in what year? Ans: 1941; Rubella
virus infection in pregnant mothers cause German measles
which lead to "congenital rubella syndrome"
Congenital Rubella Syndrome: Triad Ans: - Head: microcephaly
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- Eye: anophthalmia/microphthalmia (eyeballs missing/small)
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- Heart: PDA (patent ductus arteriosis); VSD (ventricular septal
defect)
PDA and VSD result in Ans: mixing of blood and cyanosis
Congenital rubella syndrome: eye anomalies Ans: - cataracts
- primary congenital glaucoma (high pressure in eye damages
optic nerve)
- strabismus (cross-eyed)
- nystagmus (dancing eyes)
- microphthalmia
- iris dysplasia
In the 1950s what drug was given to pregnant women to
alleviate morning sickness? Ans: Thalidomide