Stanhvlococcusaureus
Dr. Deepashree C L
Associate Professor
MRSA stands for Methicillin-resistant Staphylococcus aureus. It is type
of Staphylococcus aureus bacterium. These bacteria are resistant to common
antibiotics, including methicillin.
Morphology:
Methicillin-resistant
Staphylococcus
aureus(MRSA)is a groupof
gram-positive bacteria that are genetically distinct from
Other strains Of Staphylococcus aureus
It is ovoid or spherical cocci,
non motile, rarely capsulated.
non spore forming stain with ordinary aniline dye and is gram •eve,
I micrometer in diameter
It is arranged in clusters.
MODE OF TRANSMISSION:
Transmitted from person to person by contaminated hands.
Lack of access to hand hygiene products can increasethe risk of transmission.
Additionalrisk factorsincludes,sharingpersonalproductssuch as shampooor
nail clippers. infrequent showers and hand washing,
Unsanitary tattoo practices
In other settings close physical contact. body shaving. turf burns and sharing
athletic equipment have been associated with MRSA transmission.
Persons With asymptomatic MRSA nasal carriage can shed MRSA resulting in
transmissionto otherpersonsor contamination
of foodthat maycausetoxin
mediated acute gastroenteritis.
Path enesisand clinicalmanifestation
MRSA is responsible for several difficult-to-treat infections in humans. It caused
more than 100,000 deaths attributable to antimicrobial resistance in 2019.
MRSAis any strain of S. aureusthat has developed(throughnaturalselection)or
acquired (through horizontal gene transfer) a multiple drug resistance to beta-lactam
antibiotics.
Beta-lactam (B-lactam) antibiotics are a broad-spectrum group that include
some penams (penicillin derivatives such as methicillin and oxacillin)
and cephems such as the cephalosporms. Strains unable to resist these antibiotics are
classified as methicillin-susceptible S. aureus. or MSSA,