NSG 552 EXAM REVIEW QUESTIONS AND ANSWERS
naltrexone class - (answer)Opioid receptor antagonist
Naltrexone can be used for - (answer)both ETOH and opioid use disorders
What does naltrexone do - (answer)Reduces desire/cravings, First line treatment, Will precipitate
withdrawal in patients with physical opioid dependence
First line treatment in maintaining abstinence after detox - (answer)acamprosate
acamprosate can be used - (answer)in liver disease- not metabolized by the liver (not impacted by ETOH
use). Can be administered to patients with hepatitis, liver disease, and those who continue drinking
alcohol
acamprosate Contraindicated in - (answer)severe renal disease
acamprosate helps with - (answer)Decreasing cravings
ETOH 2nd line treatment - (answer)disulfiram (Antabuse)
disulfiram (Antabuse) causes - (answer)aversion reaction to ETOH (flushing, headaches, n/v, palpitation,
SOB, vertigo, hypotension)
disulfiram (Antabuse) Do not - (answer)administer until the person has been alcohol free at least 12
hours
disulfiram (Antabuse) MOA - (answer)Blocks enzyme (aldehyde dehydrogenase) in the liver
ETOH withdrawal- Benzos - (answer)To keep patient calm and lightly sedated
Benzos MOA - (answer)Enhance the effects of GABA
, NSG 552 EXAM REVIEW QUESTIONS AND ANSWERS
Meds used in mild alcohol withdrawal - (answer)Tegretol, Valproic or Gabapentin
ETHO meds for nutritional deficiencies - (answer)Thiamine, folic acid, and multivitamin - 'Banana bag'
Wernicke's encephalopathy treatment - (answer)Parenteral Thiamine and Folate
Wernicke's encephalopathy cause - (answer)B1 deficiency
Cocaine mechanism - (answer)reuptake of dopamine, epinephrine, and NE = Stimulant effect
Cocaine effects on the body - (answer)has vasoconstrictive effects = can cause MI, stroke
Cocaine treatment options - (answer)NO FDA approved med; Off-label = naltrexone, modafinil, Topamax
Antabuse in cocaine use disorder - (answer)increase synaptic dopamine in the brain reward circuit and
act as an agonist treatment in the setting of cocaine use disorder
Medications for cocaine-induced chest pain - (answer)nitroglycerin & aspirin = No metoprolol
Amphetamine treatment - (answer)Rehydrate, correct electrolyte, and treat hyperthermia
PCP symptoms of intoxication - (answer)Nystagmus
Sedatives intoxication treatment - (answer)Benzos = Flumazenil in OD (Benzo antagonist)
PCP treatment options - (answer)Supportive care (rehydration, electrolyte balance etc.); Benzos for
agitation, anxiety, muscle spasms; Haldol for severe agitation and psychosis
naltrexone class - (answer)Opioid receptor antagonist
Naltrexone can be used for - (answer)both ETOH and opioid use disorders
What does naltrexone do - (answer)Reduces desire/cravings, First line treatment, Will precipitate
withdrawal in patients with physical opioid dependence
First line treatment in maintaining abstinence after detox - (answer)acamprosate
acamprosate can be used - (answer)in liver disease- not metabolized by the liver (not impacted by ETOH
use). Can be administered to patients with hepatitis, liver disease, and those who continue drinking
alcohol
acamprosate Contraindicated in - (answer)severe renal disease
acamprosate helps with - (answer)Decreasing cravings
ETOH 2nd line treatment - (answer)disulfiram (Antabuse)
disulfiram (Antabuse) causes - (answer)aversion reaction to ETOH (flushing, headaches, n/v, palpitation,
SOB, vertigo, hypotension)
disulfiram (Antabuse) Do not - (answer)administer until the person has been alcohol free at least 12
hours
disulfiram (Antabuse) MOA - (answer)Blocks enzyme (aldehyde dehydrogenase) in the liver
ETOH withdrawal- Benzos - (answer)To keep patient calm and lightly sedated
Benzos MOA - (answer)Enhance the effects of GABA
, NSG 552 EXAM REVIEW QUESTIONS AND ANSWERS
Meds used in mild alcohol withdrawal - (answer)Tegretol, Valproic or Gabapentin
ETHO meds for nutritional deficiencies - (answer)Thiamine, folic acid, and multivitamin - 'Banana bag'
Wernicke's encephalopathy treatment - (answer)Parenteral Thiamine and Folate
Wernicke's encephalopathy cause - (answer)B1 deficiency
Cocaine mechanism - (answer)reuptake of dopamine, epinephrine, and NE = Stimulant effect
Cocaine effects on the body - (answer)has vasoconstrictive effects = can cause MI, stroke
Cocaine treatment options - (answer)NO FDA approved med; Off-label = naltrexone, modafinil, Topamax
Antabuse in cocaine use disorder - (answer)increase synaptic dopamine in the brain reward circuit and
act as an agonist treatment in the setting of cocaine use disorder
Medications for cocaine-induced chest pain - (answer)nitroglycerin & aspirin = No metoprolol
Amphetamine treatment - (answer)Rehydrate, correct electrolyte, and treat hyperthermia
PCP symptoms of intoxication - (answer)Nystagmus
Sedatives intoxication treatment - (answer)Benzos = Flumazenil in OD (Benzo antagonist)
PCP treatment options - (answer)Supportive care (rehydration, electrolyte balance etc.); Benzos for
agitation, anxiety, muscle spasms; Haldol for severe agitation and psychosis
