Unit 3 Exam-UNE CHEM 1005 Test
Questions Solved Correctly 2026
Updated.
An 11-year-old female is brought to the emergency department by her parent. They report she
has recently been very thirsty and needs to make frequent trips to the bathroom. Physical
examination revealed a thin girl in the 30th percentile for height and weight. A rapid dipstick
test revealed glucose in her urine. Evaluation of this girl's blood would reveal decreased levels
of which of the following compounds or hormones?
Fatty acids
Glutamine
Glucose
Ketones
Insulin - Answer Insulin
Which of the following enzymes used for ketone oxidation is not found in liver cells?
HMG-CoA synthase
Thiophorase (succinyl-CoA:acetoacetate transferase)
Thiolase (acetyl-CoA C-acetyltransferase)
β-hydroxybutyrate dehydrogenase - Answer Thiophorase (succinyl-CoA:acetoacetate
transferase)
During the fasted state, lipolysis is facilitated by the action of hormone-sensitive lipase. This
enzyme requires which of the following modifications for activation?
Allosteric activator
Phosphorylation
Cleavage
Dephosphorylation
Glycosylation - Answer Phosphorylation
A 3 day-old male is brought to the emergency department by ambulance. He is unconscious on
admission. Laboratory analysis of a blood sample shows hypoglycemia and no ketones. Blood
spot analysis showed elevation of medium chain acylcarnitines as hexanoyl carnitine (C6),
, octanoyl carnitine (C8). A urine sample was positive for dicarboxylic acids. This clinical picture is
most consistent with a defect in the:
ω-oxidation of short chain fatty acids
Carnitine transporter for long chain fatty acids
β-oxidation of medium chain fatty acids
α-oxidation of very long chain fatty acids - Answer β-oxidation of medium chain fatty acids
Short-chain fatty acids and medium-chain fatty acids enter mitochondria by:
The malate-aspartate shuttle
Diffusion
Carnitine acyl-transferase mediated transporter
GLUT - Answer Diffusion
Which of the following statements describes the role of HDL particles?
HDLs carry dietary fats and cholesterol from the intestine to the liver
HDLs transport cholesterol from peripheral tissues back to the liver
HDLs are taken up by peripheral tissues using the LDL receptor
HLDs carry triacylglycerols from the liver to the adipose for storage - Answer HDLs transport
cholesterol from peripheral tissues back to the liver
Under cellular conditions when cholesterol is low, which of the following is a true statement
regarding the sterol response element-binding protein?
It will be bound to a plasma membrane receptor
It will be targeted for degradation
It will be associated with proteins in the ER
It will be associated with the sterol response element (SRE) on the DNA - Answer It will be
associated with the sterol response element (SRE) on the DNA
A 47-year-old male is prescribed a statin (HMG-CoA reductase inhibitor) to manage his elevated
LDL cholesterol. What is the direct mechanism of action of this drug?
Decreasing intestinal absorption of dietary cholesterol
Questions Solved Correctly 2026
Updated.
An 11-year-old female is brought to the emergency department by her parent. They report she
has recently been very thirsty and needs to make frequent trips to the bathroom. Physical
examination revealed a thin girl in the 30th percentile for height and weight. A rapid dipstick
test revealed glucose in her urine. Evaluation of this girl's blood would reveal decreased levels
of which of the following compounds or hormones?
Fatty acids
Glutamine
Glucose
Ketones
Insulin - Answer Insulin
Which of the following enzymes used for ketone oxidation is not found in liver cells?
HMG-CoA synthase
Thiophorase (succinyl-CoA:acetoacetate transferase)
Thiolase (acetyl-CoA C-acetyltransferase)
β-hydroxybutyrate dehydrogenase - Answer Thiophorase (succinyl-CoA:acetoacetate
transferase)
During the fasted state, lipolysis is facilitated by the action of hormone-sensitive lipase. This
enzyme requires which of the following modifications for activation?
Allosteric activator
Phosphorylation
Cleavage
Dephosphorylation
Glycosylation - Answer Phosphorylation
A 3 day-old male is brought to the emergency department by ambulance. He is unconscious on
admission. Laboratory analysis of a blood sample shows hypoglycemia and no ketones. Blood
spot analysis showed elevation of medium chain acylcarnitines as hexanoyl carnitine (C6),
, octanoyl carnitine (C8). A urine sample was positive for dicarboxylic acids. This clinical picture is
most consistent with a defect in the:
ω-oxidation of short chain fatty acids
Carnitine transporter for long chain fatty acids
β-oxidation of medium chain fatty acids
α-oxidation of very long chain fatty acids - Answer β-oxidation of medium chain fatty acids
Short-chain fatty acids and medium-chain fatty acids enter mitochondria by:
The malate-aspartate shuttle
Diffusion
Carnitine acyl-transferase mediated transporter
GLUT - Answer Diffusion
Which of the following statements describes the role of HDL particles?
HDLs carry dietary fats and cholesterol from the intestine to the liver
HDLs transport cholesterol from peripheral tissues back to the liver
HDLs are taken up by peripheral tissues using the LDL receptor
HLDs carry triacylglycerols from the liver to the adipose for storage - Answer HDLs transport
cholesterol from peripheral tissues back to the liver
Under cellular conditions when cholesterol is low, which of the following is a true statement
regarding the sterol response element-binding protein?
It will be bound to a plasma membrane receptor
It will be targeted for degradation
It will be associated with proteins in the ER
It will be associated with the sterol response element (SRE) on the DNA - Answer It will be
associated with the sterol response element (SRE) on the DNA
A 47-year-old male is prescribed a statin (HMG-CoA reductase inhibitor) to manage his elevated
LDL cholesterol. What is the direct mechanism of action of this drug?
Decreasing intestinal absorption of dietary cholesterol
