Illustrated Reviews: Pharmacology 8th
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Edition by Karen Whalen
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COMPLETE CHAPTERS 1-48 WITH RATIONALES| A+
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100% EXPERT VERIFIED Q&As
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, 3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
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coated tablet. Which statement by the patient indicates understanding of the teaching?
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a. I may crush the tablet and put it in applesauce to improve absorption.
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b. I should consume acidic foods to enhance absorption of this medication.
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c. I should expect a delay in onset of the drugs effects after taking the tablet.
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d. I should take this medication with high-fat foods to improve its action. CORRECT ANSWER: C
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Enteric-coated tablets resist disintegration in the acidic environment of the stomach and disintegrate
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when they reach the small intestine. There is usually some delay in onset of actions after taking
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these medications. Enteric-coated tablets should not be crushed or chewed, which would alter the
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time and location of absorption. Acidic foods will not enhance the absorption of the medication. The
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patient should not to eat high-fat food before ingesting an enteric-coated tablet, because high-fat
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foods decrease the absorption rate.
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DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP: NURSING PROCESS: Nursing
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Intervention
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MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
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4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
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given by subcutaneous injection instead of by mouth. The nurse will explain that this is
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because
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a. absorption is diminished by the first-pass effects in the liver.
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b. absorption is faster when insulin is given subcutaneously.
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c. digestive enzymes in the gastrointestinal tract prevent absorption.
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d. the oral form is less predictable with more adverse effects. CORRECT ANSWER: C
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Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
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digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
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enzymes, it would not make it to the liver for metabolism with a first-pass effect. Subcutaneous
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tissue has fewer blood vessels, so absorption is slower in such tissue. Insulin is given
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subcutaneously because it is desirable to have it absorb slowly.
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DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3 TOP: NURSING PROCESS:
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Nursing Intervention: Patient Teaching
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MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
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