PHAR 501 EXAM 1 DRUGS + DOSING QUESTIONS AND
ANSWERS
Alli Generic - CORRECT ANSWER✅✅Orlistat
Alli Indicaition - CORRECT ANSWER✅✅Weight loss in overweight adults when used along with a
reduced-calorie and low-fat diet
Alli MOA - CORRECT ANSWER✅✅A reversible inhibitor of intestinal lipases
Alli Dosing - CORRECT ANSWER✅✅60 mg PO TID during or within 1 hour of each fat-containing meals
Alli Counseling Points - CORRECT ANSWER✅✅- reduced absorption of fat-soluble vitamins A,D,E,K and
beta-carotene
- doses may be skipped if a meal is missed or contains no fat
- do not take more than three times a day
- GI adverse effects decrease after the first month of therapy
TUMS generic - CORRECT ANSWER✅✅Calcium Carbonate
Antacids MOA - CORRECT ANSWER✅✅react with stomach acid to form salt (NaCl, CaCl2, Al2Cl2) and
water -> neutralizes acid, byproduct is CO2 = causes gas
Antacids Onset - CORRECT ANSWER✅✅5 minutes
Antacids Duration - CORRECT ANSWER✅✅20 mins (empty stomach) to 3 hours
Calcium Carbonate Dosing - CORRECT ANSWER✅✅Adults and Children ≥ 12 y of age: 2-4 tablets po q2h
prn (max 8g calcium carbonate per 24h).
,Children 6-11 y of age: 364 mg po q2h prn (max 966/24 h)
Children 2-5 y of age: 161 mg po q2h prn (max 483 mg/24 h)
Calcium Carbonate: Prevention or Treatment? - CORRECT ANSWER✅✅Treatment
Calcium Carbonate Class - CORRECT ANSWER✅✅Antacids
Antacids Counseling Points - CORRECT ANSWER✅✅- chewable tablets should be chewed completely
and followed with a glass of water
- dosing is product specific but should not be taken more than 4 times a day
- ADRs: diarrhea with Mg or Mg/Al products, constipation with Ca to Al products
- watch for drug interactions
Milk of Magnesia generic - CORRECT ANSWER✅✅Magnesium Hydroxide
Magnesium Hydroxide Class - CORRECT ANSWER✅✅Antacids
Magnesium Hydroxide Dosing - CORRECT ANSWER✅✅Adult and Children ≥12 y of age: 400-1200 mg po
prn up to qid
Magnesium Hydroxide: Treatment or Prevention? - CORRECT ANSWER✅✅Treatment
Magnesium Hydroxide Counseling Points - CORRECT ANSWER✅✅- Diarrhea with Mg products (Most
Common)
- Nausea, vomiting, cramping, abdominal pain, dehydration (Less Common)
- Electrolyte imbalance, fluid imbalance
- Take the product with 240 mL of liquid
, H2RAs MOA - CORRECT ANSWER✅✅Bind competitively and reversibly to H2 receptors of gastric
parietal cells --> increase gastric pH
H2RAs Onset - CORRECT ANSWER✅✅30-45 minutes
H2RAs Duration - CORRECT ANSWER✅✅4-10 hours
H2RAs ADRs - CORRECT ANSWER✅✅- Diarrhea, constipation, headache
- generally well tolerated
H2RAs Drug Interactions - CORRECT ANSWER✅✅- Cimetidine is a CYP 450 inhibitor (3A4, 2D6, 1A2, and
2C9)
- reduced absorption of ketoconazole, itraconazole, and iron in. a low-acid environment
Pepcid generic - CORRECT ANSWER✅✅Famotidine
Famotidine Class - CORRECT ANSWER✅✅H2RAs
Famotidine Dosing - CORRECT ANSWER✅✅Adults and Children ≥ 12 y of age: 10-20 mg po bid for up to
14 d; max 40 mg/d
Famotidine: Treatment or Prevention? - CORRECT ANSWER✅✅Both
Prevention: 15-60 minutes before known irritating foods
PPI MOA - CORRECT ANSWER✅✅Bind irreversibly to H+/K+ ATPase pump (proton pump) in gastric
parietal cells --> inhibition of gastric acid secretion
PPI Onset - CORRECT ANSWER✅✅2-3 hours
ANSWERS
Alli Generic - CORRECT ANSWER✅✅Orlistat
Alli Indicaition - CORRECT ANSWER✅✅Weight loss in overweight adults when used along with a
reduced-calorie and low-fat diet
Alli MOA - CORRECT ANSWER✅✅A reversible inhibitor of intestinal lipases
Alli Dosing - CORRECT ANSWER✅✅60 mg PO TID during or within 1 hour of each fat-containing meals
Alli Counseling Points - CORRECT ANSWER✅✅- reduced absorption of fat-soluble vitamins A,D,E,K and
beta-carotene
- doses may be skipped if a meal is missed or contains no fat
- do not take more than three times a day
- GI adverse effects decrease after the first month of therapy
TUMS generic - CORRECT ANSWER✅✅Calcium Carbonate
Antacids MOA - CORRECT ANSWER✅✅react with stomach acid to form salt (NaCl, CaCl2, Al2Cl2) and
water -> neutralizes acid, byproduct is CO2 = causes gas
Antacids Onset - CORRECT ANSWER✅✅5 minutes
Antacids Duration - CORRECT ANSWER✅✅20 mins (empty stomach) to 3 hours
Calcium Carbonate Dosing - CORRECT ANSWER✅✅Adults and Children ≥ 12 y of age: 2-4 tablets po q2h
prn (max 8g calcium carbonate per 24h).
,Children 6-11 y of age: 364 mg po q2h prn (max 966/24 h)
Children 2-5 y of age: 161 mg po q2h prn (max 483 mg/24 h)
Calcium Carbonate: Prevention or Treatment? - CORRECT ANSWER✅✅Treatment
Calcium Carbonate Class - CORRECT ANSWER✅✅Antacids
Antacids Counseling Points - CORRECT ANSWER✅✅- chewable tablets should be chewed completely
and followed with a glass of water
- dosing is product specific but should not be taken more than 4 times a day
- ADRs: diarrhea with Mg or Mg/Al products, constipation with Ca to Al products
- watch for drug interactions
Milk of Magnesia generic - CORRECT ANSWER✅✅Magnesium Hydroxide
Magnesium Hydroxide Class - CORRECT ANSWER✅✅Antacids
Magnesium Hydroxide Dosing - CORRECT ANSWER✅✅Adult and Children ≥12 y of age: 400-1200 mg po
prn up to qid
Magnesium Hydroxide: Treatment or Prevention? - CORRECT ANSWER✅✅Treatment
Magnesium Hydroxide Counseling Points - CORRECT ANSWER✅✅- Diarrhea with Mg products (Most
Common)
- Nausea, vomiting, cramping, abdominal pain, dehydration (Less Common)
- Electrolyte imbalance, fluid imbalance
- Take the product with 240 mL of liquid
, H2RAs MOA - CORRECT ANSWER✅✅Bind competitively and reversibly to H2 receptors of gastric
parietal cells --> increase gastric pH
H2RAs Onset - CORRECT ANSWER✅✅30-45 minutes
H2RAs Duration - CORRECT ANSWER✅✅4-10 hours
H2RAs ADRs - CORRECT ANSWER✅✅- Diarrhea, constipation, headache
- generally well tolerated
H2RAs Drug Interactions - CORRECT ANSWER✅✅- Cimetidine is a CYP 450 inhibitor (3A4, 2D6, 1A2, and
2C9)
- reduced absorption of ketoconazole, itraconazole, and iron in. a low-acid environment
Pepcid generic - CORRECT ANSWER✅✅Famotidine
Famotidine Class - CORRECT ANSWER✅✅H2RAs
Famotidine Dosing - CORRECT ANSWER✅✅Adults and Children ≥ 12 y of age: 10-20 mg po bid for up to
14 d; max 40 mg/d
Famotidine: Treatment or Prevention? - CORRECT ANSWER✅✅Both
Prevention: 15-60 minutes before known irritating foods
PPI MOA - CORRECT ANSWER✅✅Bind irreversibly to H+/K+ ATPase pump (proton pump) in gastric
parietal cells --> inhibition of gastric acid secretion
PPI Onset - CORRECT ANSWER✅✅2-3 hours
