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Medical-Surgical RN A Prophecy Relias 2026/2027 | Actual Questions & Verified Answers | Med-Surg Exam Prep

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Complete study guide for the Medical-Surgical RN A Prophecy/Relias Exam (2026/2027 Latest Update). Features over 200 verified questions and answers covering essential med-surg nursing topics including cardiac care (MI, heart failure, atrial fibrillation, hypertension), respiratory disorders (COPD, pneumonia, pulmonary embolism, TB), neurological conditions (CVA/stroke, increased ICP, seizures, delirium), endocrine emergencies (diabetes DKA/hypoglycemia, thyroid disorders), renal and urology (UTI, CAUTI, TURP, CKD), GI disorders (diverticulitis, cholecystitis, bowel obstruction, pancreatitis), infection control (C. diff, MRSA, PPE, isolation precautions), pharmacology (digoxin, warfarin, insulin, opioids, statins), perioperative care, fluid and electrolyte imbalances, and nursing prioritization. Essential for RN med-surg certification, Prophecy testing, and Relias competency assessments.

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MEDICAL-SURGICAL RN A PROPHECY
RELIAS LATEST QUESTIONS AND
ANSWERS
FULLY VERIFIED | NURSING EXAM
PREP RESOURCE 2026/2027




1. Your 85-year-old patient with atrial fibrillation fell at home 3 days ago. You notice she has been
having several episodes of acute confusion since being admitted to your unit. What is the MOST
important order you should anticipate from the provider?
A. Routine blood work

B. Stat CT of head

C. MRI of the brain

D. X-ray of the pelvis

Answer: B. Stat CT of head


2. Your patient has a temp of 102.3 F, HR 122, and has had 15 mL of urine from the indwelling urinary
catheter in the last 2 hours. What is your patient MOST likely experiencing?


1

, A. Dehydration

B. Heart failure

C. Sepsis

D. Fever

Answer: C. Sepsis


3. What type of personal protective equipment (PPE) is applied prior to entering a room for a
patient with C. diff? A. Mask and gloves
B. Gown and gloves

C. Face shield and goggles

D. No PPE required

Answer: B. Gown and gloves


4. Your patient continues to pull at their IV site located in their left forearm despite verbal reminders
and increased observation. The nursing assistant recommends using soft mitt restraints on the
patient. What is your recommendation?
A. Request an order for soft mitts as they are the least restrictive

B. Use hard restraints

C. Ignore the recommendation

D. Allow the patient to pull at their IV

Answer: A. Request an order for soft mitts as they are the least restrictive


5. Your patient was admitted for a hypertensive crisis and has a history of HTN, Parkinson's
disease, depression, and alcohol use. On his second hospitalized day, you notice he is more
anxious and restless than his baseline. What would be your FIRST nursing intervention?


2

, A. Ask the patient when his last drink of alcohol was

B. Administer anxiety medication

C. Call the psychiatrist

D. Document your observations

Answer: A. Ask the patient when his last drink of alcohol was


6. What is the BEST indication of an acute neurological problem?

A. Change in level of consciousness

B. Severe headache

C. Loss of motor function

D. Tingling sensations

Answer: A. Change in level of consciousness


7. While in a supine position your patient states, "I'm tired and cannot catch my breath." Physical
assessment reveals jugular vein distention and a third heart sound (S3). These symptoms are
indicative of what condition?
A. Myocardial infarction

B. Heart failure

C. Pulmonary embolism

D. Pneumothorax

Answer: B. Heart failure


8. Your new admission presents with a cough, unintentional weight loss, frequent night sweats, and
bloody sputum. What type of isolation precautions should you initiate, if any?


3

, A. Contact precautions

B. Droplet precautions

C. Airborne precautions

D. No isolation required

Answer: C. Airborne precautions


9. Patients with diabetes are at high risk for complications from damage to what body areas? A.
Lungs and heart

B. Skin and muscles

C. Nerve and kidney damage

D. Liver and pancreas

Answer: C. Nerve and kidney damage




10. 1.2 milligrams is equal to how many micrograms?

A. 1200 mcg

B. 120 mcg

C. 12,000 mcg

D. 1,200,000 mcg

Answer: A. 1200 mcg


11. Your post-op patient has a Jackson-Pratt (JP) drain in place. How do you ensure effective drain
function?
A. Keep the drain open


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