d) The regulation of gene expression through heritable modifications in chromatin structure
is called:
a) Gene regulation
b) Signal transduction
c) Transcriptional regulation
d) Epigenetic regulation
c) A/an i) _________ functions by binding ii) __________ elements to increase transcription in a gene
specific manner.
a) i) transcription factor; ii) promoter
b) i) basal transcription apparatus; ii) conserved
c) i) activator; ii) enhancer
d) i) promoter; ii) transcription
e) i) enhancer ; ii) general promoter
RNA pol 3 I synthesize tRNA, what polymerase am I?
a) What promoter element would you expect to find upstream of a gene that is highly
expressed?
a) TATA box
b) DPE
c) Initiator box
d) CpG islands
1) The TBP subunit of TFIID binds the TATA box, bending DNA state the steps of the assembly of the pre-initiation complex (there are 4)
2) TFIIA and TFIIB bind
3) A preformed complex of TFIIF and RNA pol II bind
4) TFIIE binds creating a docking site for TFIIH, which then
binds.
, TF2A and TF2B The general transcription factors
________ and _______ both join the initiation complex after TFIID. Binding both DNA and TBP
1) TFIIH binds the pre-initiation complex. State the following steps of the transition from transcriptional initiation to elongation (
there are 5)
2) Energy from ATP hydrolysis is used to unwind the DNA at
the transcription start site, forming the transcription bubble.
3) RNA pol II begins synthesizing RNA.
4) TFIIH kinase phosphorylates the CTD of RNA pol II.
5) The pre-initiation complex disassembles leaving only TFIID
bound to the promoter.
3) and 4) Which of the following is a function of a promoter? Select all that apply.
1) regulate the rate of replication
2) regulate the efficiency of translation
3) provide a binding site for transcription factors
4) position the +1 site
5)provide a binding site for the ribosome
3) Which of the following is NOT a conserved eukaryotic promoter element ?
1) TATA box
2) GC box
3) Initiator box
4) CAAT box
RNA pol I I synthesize pre-rRNA, what polymerase am I?
H1 Which histone protein is not part of the nucleosome octamer core?
H4
H2b
H3
H2a
H1
is called:
a) Gene regulation
b) Signal transduction
c) Transcriptional regulation
d) Epigenetic regulation
c) A/an i) _________ functions by binding ii) __________ elements to increase transcription in a gene
specific manner.
a) i) transcription factor; ii) promoter
b) i) basal transcription apparatus; ii) conserved
c) i) activator; ii) enhancer
d) i) promoter; ii) transcription
e) i) enhancer ; ii) general promoter
RNA pol 3 I synthesize tRNA, what polymerase am I?
a) What promoter element would you expect to find upstream of a gene that is highly
expressed?
a) TATA box
b) DPE
c) Initiator box
d) CpG islands
1) The TBP subunit of TFIID binds the TATA box, bending DNA state the steps of the assembly of the pre-initiation complex (there are 4)
2) TFIIA and TFIIB bind
3) A preformed complex of TFIIF and RNA pol II bind
4) TFIIE binds creating a docking site for TFIIH, which then
binds.
, TF2A and TF2B The general transcription factors
________ and _______ both join the initiation complex after TFIID. Binding both DNA and TBP
1) TFIIH binds the pre-initiation complex. State the following steps of the transition from transcriptional initiation to elongation (
there are 5)
2) Energy from ATP hydrolysis is used to unwind the DNA at
the transcription start site, forming the transcription bubble.
3) RNA pol II begins synthesizing RNA.
4) TFIIH kinase phosphorylates the CTD of RNA pol II.
5) The pre-initiation complex disassembles leaving only TFIID
bound to the promoter.
3) and 4) Which of the following is a function of a promoter? Select all that apply.
1) regulate the rate of replication
2) regulate the efficiency of translation
3) provide a binding site for transcription factors
4) position the +1 site
5)provide a binding site for the ribosome
3) Which of the following is NOT a conserved eukaryotic promoter element ?
1) TATA box
2) GC box
3) Initiator box
4) CAAT box
RNA pol I I synthesize pre-rRNA, what polymerase am I?
H1 Which histone protein is not part of the nucleosome octamer core?
H4
H2b
H3
H2a
H1
