CHEM 1005 GENERAL CHEMISTRY FOR PRE-NURSING AND
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
CHEM 1005 General Chemistry for Pre-Nursing and Pre-Allied
Health final exam Latest Version 2026/2027| Questions and
Correct Answers (Verified, exam of Nursing
A 12-year-old male is brought to his primary care physician. His parents are concerned with his recent
decline in school work due to persistent blurred vision. On physical exam, planar xanthomas are noted
and laboratory testing reveals extremely low plasma HDL. This presentation would be consistent with a
loss of which of the following apoproteins?
A. ApoE
B. ApoA
C. ApoB100
D. ApoB48
Glutamate can be deaminated by which of the following enzymes:
A. Glutamine synthetase
B. Glutamate dehydrogenase (GDH)
C. Glutaminase
D. Arginase
The transamination of all amino acids requires which of the following cofactors?
A. Thiamine
B. Folate
C. N-acetyl glutamate
D. Pyridoxal phosphate (PLP)
2/25/2026
1
, CHEM 1005 GENERAL CHEMISTRY FOR PRE-NURSING AND
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
A healthy, well-nourished male consumes a protein-rich meal. Several hours later, the majority of the
nitrogen atoms from the protein in his diet would most likely be incorporated into which of the
following compounds?
A. Urea
B. Ketone bodies
C. Glycogen
D. Nucleotides
Which of the following enzymes is regulated by N-acetyl glutamate (NAG)?
A. Carbamoyl phosphate synthetase I (CPS I)
B. Argininosuccinate lyase
C. Carbamoyl phosphate synthetase II (CPS II)
D. Ornithine transcarbamylase
Two hikers get lost in the woods, they have not brought any snacks or water with them. As time passes
their insulin to glucagon ratio decreases. 24 hours into their fast you would expect the enzymatic activity
of both _________ and ________ to be elevated in the liver.
A. Glutaminase and carbamoyl phosphate synthetase I
B. Glycogen synthase and carnitine palmitoyltransferase I
C. Glutamine synthase and Phosphofructokinase 2 (PFK2)
D. PEP carboxykinase (PEPCK) and pyruvate kinase
The urea cycle takes place in which of the following subcellular locations?
A. The cytosol only
2/25/2026
B. The mitochondria only
C. The nucleus and mitochondria
2
, CHEM 1005 GENERAL CHEMISTRY FOR PRE-NURSING AND
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
D. The cytosol and the mitochondria
Select the choice that correctly indicates the proper sequence of the three stages of urea biosynthesis
leading to the urea cycle.
A. oxidative deamination of glutamate → ammonia transport → transamination
B. transamination → ammonia transport → oxidative deamination of glutamate
C. ammonia transport → oxidative deamination of glutamate → transamination
D. transamination → oxidative deamination of glutamate → ammonia transport
Which of the following enzymes is the regulatory step in the urea cycle?
A. Argininosuccinate lyase
B. Ornithine transcarbamylase
C. Arginase
D. Carbamoyl phosphate synthetase I (CPS I)
An elevation of homocysteine and a decrease in cysteine would most likely be present due to which of
the following deficiencies?
A. Cobalamin deficiency
B. Loss of function of methionine synthase
C. Tetrahydrobiopterin (BH4) deficiency
D. Loss of function of cystathionine-β synthase
2/25/2026
Hypopigmentation disorder is primarily due to deficient metabolism of which of the following amino
acids?
3
, CHEM 1005 GENERAL CHEMISTRY FOR PRE-NURSING AND
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
A. Homocysteine
B. Cysteine
C. Methionine
D. Arginine
E. Tyrosine
In an individual with a deficiency in the branched-chain ketoacid dehydrogenase complex, metabolism
of which of the following amino acids would not likely be impaired?
A. Valine
B. Tyrosine
C. Isoleucine
D. Leucine
Metabolism of _____________________ leads to the synthesis of __________________.
A. Glycine ; epinephrin
B. Threonine ; norepinephrine
C. Tyrosine ; serotonin
D. Alanine ; homocysteine
E. Tryptophan ; melatonin
A deficiency in which of the following enzymes would impair the production of S-adenosylmethionine
2/25/2026
(SAM)?
A. Phenylalanine hydroxylase
4
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
CHEM 1005 General Chemistry for Pre-Nursing and Pre-Allied
Health final exam Latest Version 2026/2027| Questions and
Correct Answers (Verified, exam of Nursing
A 12-year-old male is brought to his primary care physician. His parents are concerned with his recent
decline in school work due to persistent blurred vision. On physical exam, planar xanthomas are noted
and laboratory testing reveals extremely low plasma HDL. This presentation would be consistent with a
loss of which of the following apoproteins?
A. ApoE
B. ApoA
C. ApoB100
D. ApoB48
Glutamate can be deaminated by which of the following enzymes:
A. Glutamine synthetase
B. Glutamate dehydrogenase (GDH)
C. Glutaminase
D. Arginase
The transamination of all amino acids requires which of the following cofactors?
A. Thiamine
B. Folate
C. N-acetyl glutamate
D. Pyridoxal phosphate (PLP)
2/25/2026
1
, CHEM 1005 GENERAL CHEMISTRY FOR PRE-NURSING AND
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
A healthy, well-nourished male consumes a protein-rich meal. Several hours later, the majority of the
nitrogen atoms from the protein in his diet would most likely be incorporated into which of the
following compounds?
A. Urea
B. Ketone bodies
C. Glycogen
D. Nucleotides
Which of the following enzymes is regulated by N-acetyl glutamate (NAG)?
A. Carbamoyl phosphate synthetase I (CPS I)
B. Argininosuccinate lyase
C. Carbamoyl phosphate synthetase II (CPS II)
D. Ornithine transcarbamylase
Two hikers get lost in the woods, they have not brought any snacks or water with them. As time passes
their insulin to glucagon ratio decreases. 24 hours into their fast you would expect the enzymatic activity
of both _________ and ________ to be elevated in the liver.
A. Glutaminase and carbamoyl phosphate synthetase I
B. Glycogen synthase and carnitine palmitoyltransferase I
C. Glutamine synthase and Phosphofructokinase 2 (PFK2)
D. PEP carboxykinase (PEPCK) and pyruvate kinase
The urea cycle takes place in which of the following subcellular locations?
A. The cytosol only
2/25/2026
B. The mitochondria only
C. The nucleus and mitochondria
2
, CHEM 1005 GENERAL CHEMISTRY FOR PRE-NURSING AND
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
D. The cytosol and the mitochondria
Select the choice that correctly indicates the proper sequence of the three stages of urea biosynthesis
leading to the urea cycle.
A. oxidative deamination of glutamate → ammonia transport → transamination
B. transamination → ammonia transport → oxidative deamination of glutamate
C. ammonia transport → oxidative deamination of glutamate → transamination
D. transamination → oxidative deamination of glutamate → ammonia transport
Which of the following enzymes is the regulatory step in the urea cycle?
A. Argininosuccinate lyase
B. Ornithine transcarbamylase
C. Arginase
D. Carbamoyl phosphate synthetase I (CPS I)
An elevation of homocysteine and a decrease in cysteine would most likely be present due to which of
the following deficiencies?
A. Cobalamin deficiency
B. Loss of function of methionine synthase
C. Tetrahydrobiopterin (BH4) deficiency
D. Loss of function of cystathionine-β synthase
2/25/2026
Hypopigmentation disorder is primarily due to deficient metabolism of which of the following amino
acids?
3
, CHEM 1005 GENERAL CHEMISTRY FOR PRE-NURSING AND
PRE-ALLIED HEALTH FINAL EXAM LATEST VERSION 02/25/2026
2026/2027
A. Homocysteine
B. Cysteine
C. Methionine
D. Arginine
E. Tyrosine
In an individual with a deficiency in the branched-chain ketoacid dehydrogenase complex, metabolism
of which of the following amino acids would not likely be impaired?
A. Valine
B. Tyrosine
C. Isoleucine
D. Leucine
Metabolism of _____________________ leads to the synthesis of __________________.
A. Glycine ; epinephrin
B. Threonine ; norepinephrine
C. Tyrosine ; serotonin
D. Alanine ; homocysteine
E. Tryptophan ; melatonin
A deficiency in which of the following enzymes would impair the production of S-adenosylmethionine
2/25/2026
(SAM)?
A. Phenylalanine hydroxylase
4
