IBHRE clinical trials and ind Questions and Correct
Answers | Latest Update
Characteristics of Heart Failure
Ans: Heart failure can result from any structural or functional cardiac
disorder that impairs ability of ventricle to fill with or eject blood.
What causes a higher than normal ejection fraction?
Ans: Hypertrophic Cardiomyopathy
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Systolic Failure =
Ans: Decreased contractility
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Diastolic Failure =
Ans: Think Decreased filing
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Cardiac Output (CO)
Ans: HR X SV / 1000
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Normal range = 4.0 - 8.0 l/min
CO = becomes insufficient to meet metabolic demand
Stroke Volume (SV)
Ans: CO / HR x 1000
Normal Range = 60-100 ml/beat
SV = determined by preload, afterload and myocardial contractility.
Ejection Fraction (EF)
Ans: SV / EDV (end-diastolic volume)
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Normal Range = 55-75%
EF = < 40%
What are the three classifications of HF?
Ans: Systolic Failure - decreased contractility
Diastolic Failure - decreased filing
Combination of both systolic and diastolic (mixed)
Systolic
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Ans: (think Pumping or squeezing)
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Caused by depressed myocardial contractility
Approximately two-thirds of heart failure patients have systolic
dysfunction
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Diastolic
Ans: (think Filling)
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Caused by the hearts inability to stretch and fill.
The muscle wall is thick and the chamber is narrowed.
What is the prevalence and incidence of Heart Failure?
Ans: According to CDC:
5.7M adults have HF
One in nine deaths in 2009 had HF as a contributing cause.
About 1/2 of people who develop HF die within five years of diagnosis.
HF costs the nation $30.7 billion each year.