NURS 6015 Exam #2 Questions and Correct Answers
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successful treatment with bacteriostatic antibiotics depends upon what
factor? Ans: adequate duration of drug therapy
a client is receiving aminoglycoside therapy. The nurse would be alert for
Ans: kidney dysfunction
bacitracin interfere with the cell wall synthesis of which type of bacteria?
Ans: staphylococcal
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amino glycoside antibiotics tend to collect in the eighth cranial nerve. the
nurse would anticipate that which clinical manifestation may occur from
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the cranial nerve involvement? Ans: vertigo
what occurs when the normal flora is destroyed by the use of anti-
infectives? Ans: superinfection
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the nurse is caring for several medical clients who have infections. for
which client would the administration of a broad spectrum antibiotic be
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most appropriate? Ans: a client with signs of infection who is awaiting
the results of laboratory testing
the nurse is caring for a client with pericarditis who has been prescribed
vancomycin 1000 mg IV q12h. when assessing the client for adverse
effects, the nurse should perform what assessments? Ans: -assess the
client for any auditory changes
-monitor the clients during output, blood urea nitrogen and creatinine
the hospital nurse is caring for a group of adult clients. for which client
should the nurse most likely administer prophylactic anti-infectives?
Ans: a client with colorectal cancer who is preoperative for a bowel
resection
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a client has been diagnosed with an infection. the nurse can help to
ensure the success of anti-infective treatment by Ans: confirming that
medication prescribed is the drug of choice for the specific
microorganism
a nurse is caring for a client who is hospitalized for pneumonia. the
nurse reviews the electronic health record and evaluates that the
microbiology data does not support the use of the broad spectrum
antibiotics. which statement is the nurse's best response to the provider
about the results? Ans: the microbiology data is identifying another
antibiotic appropriate for the client
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selective toxicity Ans: the ability to affect certain proteins or enzyme
systems that are used by the infecting organism but not by the human
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cells
spectrum Ans: the range of bacteria against which can antibiotic is
effective (broad spectrum antibiotics are effective against a wide range of
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bacteria, narrow-spectrum antibiotics are effective only against very
selective bacteria
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antiinfective agents Ans: are drugs designed to target foreign organisms
that have invaded and infected the body of a human host
although antiinfective agents target foreign organisms infecting the body
of a human host, they do not possess total selective toxicity which is the?
Ans: ability to affect certain proteins or enzyme systems used only by
the infecting organism but not by the human cells
some people believe that the habitual use of antibiotics for what might
well be a viral infection has contributed to? Ans: the development of
resistant strains
children have an increased susceptibility to the GI and nervous system
effects of antiinfectives, the nurse should monitor? Ans: nutritional and
hydration status
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extreme caution must be exercised in the use of antiinfective in pregnant
and nursing women because? Ans: they can affect the fetus and also
cross into breast milk leading to toxic effects in the neonate
antiinfectives that adversely affect the liver and kidneys must be used in
caution with __ patients, who may have decreased organ function Ans:
older
the goal of antiinfective agents is to? Ans: interfere with the normal
function of the invading organism to prevent it from reproducing and to
cause cell death without affecting host cells
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antiinfectives can affect cells by? Ans: -disrupting the cell membrane
-interfering with DNA synthesis
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-altering RNA
-blocking the use of essential nutrients
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some antiinfectives interfere with biosynthesis of the pathogen cell wall.
because bacterial cells have a slightly different composition than human
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cells this is an effective way to destroy the bacteria without interfering
with the host the __ are on classification of antibiotic that work in this
way. Ans: PCN
some antiinfectives prevent the cells of the invading organism from
using substances essential to their growth and development leading to
the inability to divide and eventually to cell death. what are some drugs
that work in this way? Ans: -sulfonamides
-antimycobacterial drugs
-trimethoprim-sulfamethoxazole (combination drug used to treat UTIs)
many antiiinfectives interfere with the steps involved in protein
synthesis a function necessary to maintain the cell and allow for cell
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divison what are some drugs that work in this way? Ans: -
aminoglycosides
-macrolides
some antiinfectives interfere with DNA synthesis in the cell, leading to
the inability to divide and cell death what are some drugs that work in
this way? Ans: fluoroquinolones
other antiinfectives alter the permeability of the cell membrane to allow
essential cellular components to leak out, causing cell death what are
some drugs that work in this way? Ans: antibiotics
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-antifungals
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-antiprotozoal
some antiinfectives are so selective in their action that they are effective
against only a few microorganisms with a very specific metabolic
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pathway or enzymes these drugs are said to have a? Ans: narrow
spectrum of activity
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other drugs interfere with biochemical reactions in many different kind
of microorganisms, making them useful in the treatment of a wide
variety of infections such drugs are said to have a? Ans: broad spectrum
of activity
some antiinfectives are so active against the infective microorganism that
they actually cause the death of the cell they affect these drugs are said
to be? Ans: bactericidal
some antiinfectives are not as aggressive against invading organisms
they interfere with the ability of the cell to reproduce or divide these
drugs are said to be? Ans: bacteriostatic