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(BRADLEY UNIVERSITY) || ||
Which of the types of chemical bonding between drugs and their receptors is the least
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common? - ✔✔Covalent || ||
Which type of drug classification is most important to the practitioner? -
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✔✔Therapeutic
Mechanism of Action - ✔✔The manner in which molecular targets are affected by the
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drug
Adverse Drug Reaction (ADR) can lead the patient to - ✔✔stop taking the drug
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Half-life is defined as - ✔✔The time required for the plasma concentration of a drug
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to be reduced by 50 percent
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When one drug is more efficacious than another, it has... - ✔✔A greater ability to
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initiate a response || ||
What is bioavailability? - ✔✔The fraction of unchanged drug that reaches the systemic
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circulation following administration by any route
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Absorption is defined as: - ✔✔The transfer of a drug from its site of administration to
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the blood ||
How can Competitive antagonism be overcome? - ✔✔by adding more agonist
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, How is children's dosing most often calculated? - ✔✔MG/KG
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A patient complains of pain from a migraine. How would the practitioner classify this
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type of pain? - ✔✔Central Neuropathic Pain
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What stage of nociception is occurring when neurotransmitters in the dorsal horn
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directly or indirectly depolarize the second-order neurons? - ✔✔Trasmission
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What are the four processes of Nociception - ✔✔transduction, transmission,
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modulation, and perception || ||
A practitioner conducting a pain assessment asks the patient, "Is the pain consistent
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or intermittent?" What character of pain is the practitioner assessing? - ✔✔Temporal
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pattern
What is the maximum dose of acetaminophen in 24 hours? - ✔✔4 grams
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Etodolac is in the same drug class as ibuprofen. What is its mechanism of action? -
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✔✔It inhibits the cyclooxygenase enzyme.
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What kind of drug is Naloxone (Narcan) - ✔✔opioid antagonist
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Acetaminophen and alcohol have a complex relationship in the liver. Why? (3 reasons) || || || || || || || || || || || ||
- ✔✔1. They are both metabolized by the same liver enzyme.
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2. Alcohol inhibits the enzyme that metabolizes acetaminophen.
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3. The enzyme that metabolizes acetaminophen is induced by alcohol.
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