NR 567 – Advanced Pharmacology for Acute and Critical Care: Emergency Neurologic Management, Toxicology Antidotes, Antiseizure Therapy in Pregnancy, Status Epilepticus Treatment, Sedative-Hypnotics and Benzodiazepine Reversal, Antipsychotic Adverse Effect

NR 567 – Advanced Pharmacology for Acute and Critical Care: Emergency Neurologic Management, Toxicology Antidotes, Antiseizure Therapy in Pregnancy, Status Epilepticus Treatment, Sedative-Hypnotics and Benzodiazepine Reversal, Antipsychotic Adverse Effects, Anesthetic Agents Neuromuscular Blocking Drugs, Opioid Agonists and Antagonists, and Cardiovascular Pharmacotherapy – Final Comprehensive Exam Questions Verified and Provided with Complete A+ Graded Rationales Latest Updated 2026 Which of the following medications should be given to patients presenting to the emergency department (ED) with an altered level of consciousness, seizures, or both, if a concern of Wernicke-Korsakoff syndrome exists? Thiamine Which of the following pharmaceutical agents is not recommended for treating methanol poisoning? Antabuse Which of the following pharmaceutical agents is the preferred antiseizure medication for a generalized seizure disorder in a 25-year -old pregnant female? Levetiracetam (Keppra) Which of the following is the least preferable initial treatment of choice for status epilepticus? Propofol (Diprivan) Which of the following statements is not true? Sedative hypnotics can be utilized as an anticonvulsant; zolpidem (Ambien) and lorazepam (Ativan) are excellent options for managing seizures.- Zolpidem is not used as an anti-seizure Your patient has been taking risperidone (Risperdal) but has developed hyperprolactinemia. Which of the following may help manage hyperprolactinemia? Bromocriptine (Parlodel) A 35-year-old female with a long history of anxiety treated with diazepam (Valium) has increasingly become fearful and anxious about the Coronavirus pandemic and triples her daily dose. She is found extremely lethargic and obtunded two days after the increased dosing. Which of the following pharmaceutical agents should the nurse practitioner order to treat her condition? Flumazenil (Romazicon) A 25-year-old male with a history of bipolar disease presents to the emergency department (ED) with acute agitation characteristic of mania. Non-pharmacological methods of de-escalation have been attempted without success. Which of the following is not recommended to treat this patient? Olanzapine (Zyprexa) Which of the following is a long-acting benzodiazepine that is used to treat anxiety? Diazepam (Valium) Acute dystonia can develop after early initiation of which of the following? halodol Adding epinephrine to a local anesthetic, such as 1% lidocaine for local infiltration, has which of the following benefits? Extends the duration of the anesthesia block, useful for longer procedures Your patient reports a history of anaphylaxis to an "ester-type" local anesthetic. Which of the following, if given, would be most likely to provoke an allergic response in this patient? Tetracaine (Pontocaine) An OR patient receives propofol for induction. What is the most likely adverse response associated with the administration of this pharmaceutical agent? Hypotension and respiratory depression Which of the following is the least appropriate medication for a patient with suspected increased intracranial pressure? Ketamine (Ketalar) It is noted that a trauma ICU patient is receiving adequate pain relief during painful procedures, but has increased skeletal muscle tone, an elevation in HR and BP, and post-procedure hallucinations and agitation as the drug wears off. Which of the following pharmaceutical agents is likely to create these effects? Ketamine (Ketalar) You are managing a patient who presented to the emergency department with a severe headache. Shortly upon arrival, the patient's neurological status rapidly deteriorates requiring airway management. Rapid sequence intubation is performed, and the patient suddenly develops a fever, hypertension, tachycardia, metabolic acidosis, hyperkalemia, and muscle rigidity. Which induction agent was most likely used? Succinylcholine chloride You are selecting a neuromuscular blocking agent with the least cardiovascular side effect profile for an elderly patient with coronary artery disease. Which of the following medications should be avoided? Pancuronium (Pavulon) Your ICU patient is admitted following multisystem trauma secondary to a motor vehicle collision. The patient is ventilated and will be maintained on a neuromuscular blocking continuous agent to maintain neuromuscular blockage and deep sedation. Which of the following is a true statement? If dantrolene is needed postoperatively on the NMBA, care should be taken to ensure muscle strength has returned prior to extubation Which of the following best describes the rationale for long-term methadone therapy in treating opioid addiction and abuse? Methadone has greater oral bioavailability than morphine Which of the following is a pure opioid antagonist that binds competitively to opioid receptors, does not produce analgesia or opioid side effects, and reverses the toxic effects of agonist and agonist-antagonist opioids? Naloxone (Narcan) Your patient presents with essential hypertension, and in reviewing lab results, you note that the circulating plasma renin and catecholamine levels are high. You decide to lower blood pressure by reducing both cardiac output and systemic vascular resistance (blocking both alpha- and beta-adrenergic