PORTAGE
PATHOPHYSIOLOGY
MODULE 10 EXAM
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, Question 1
Which of the following drugs is most commonly prescribed to treat osteoporosis?
Correct Answer
alendronate
Rationale:
Alendronate is the correct choice because it is a bisphosphonate, a class of medications specifically designed to inhibit bone resorption
and increase bone density, making it highly effective in treating osteoporosis. Its mechanism of action and established efficacy in
clinical trials and real-world applications have led to its widespread prescription as a first-line treatment for osteoporosis.
Question 2
A 22-year-old competitive gymnast has experienced amenorrhea for the past 5 years. Her PCP is suspecting that she
may have premature osteoporosis. Would you expect her OPG levels to be high, normal, or low? Explain why her levels
would be at this level.
Correct Answer
Her OPG levels would be low. Amenorrhea results in lower estrogen levels. Estrogen increases the production of OPG
in turn decreasing osteoclast activity. If estrogen levels are low, OPG levels would also be low resulting in increased
osteoclast activity.
Rationale:
Amenorrhea leads to lower estrogen levels, which in turn results in decreased production of Osteoprotegerin (OPG). With lower OPG
levels, osteoclast activity increases, as OPG normally helps to inhibit osteoclast activity, making it more likely for the 22-year-old
gymnast to experience premature osteoporosis.
Question 3
A patient presents to the ER with severe pain in their right ankle. Blood tests reveal serum uric acid levels of 7.8
mg/dL. They are kept for observation and their 24-hr urine specimen reveals underexcretion of urate. Which phase of
gout are they in? What is the goal of your treatment given the phase they are in?
Correct Answer
This patient is in phase 2 of gout or acute gout arthritis. The goal of treatment is to manage symptoms and terminate
the acute attack primarily through NSAIDS.
Rationale:
The patient is in phase 2 of gout because they are experiencing an acute gout attack, indicated by severe pain in their ankle, and their
24-hr urine specimen reveals underexcretion of urate, a key factor in gout development. The goal of treatment is to manage
symptoms and terminate the acute attack primarily through NSAIDs, as phase 2 is focused on acute management and symptom relief,
rather than addressing the underlying pathophysiology or preventing future attacks.
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PATHOPHYSIOLOGY
MODULE 10 EXAM
25+ (Updated for 2026) Exam Prep
Pack | A+ Questions & Verified Answers
100% Guarantee Pass
This Exam contains: portage pathophysiology
✓ module 10 exam
✓ 100% Accurate Questions and Answers
✓ 100% Guarantee Pass - Verified by Experts
✓ Each Question Includes The Correct Answer
✓ Expert-Verified
Trusted by thousands of students and professionals worldwide Page 1 of 9
, Question 1
Which of the following drugs is most commonly prescribed to treat osteoporosis?
Correct Answer
alendronate
Rationale:
Alendronate is the correct choice because it is a bisphosphonate, a class of medications specifically designed to inhibit bone resorption
and increase bone density, making it highly effective in treating osteoporosis. Its mechanism of action and established efficacy in
clinical trials and real-world applications have led to its widespread prescription as a first-line treatment for osteoporosis.
Question 2
A 22-year-old competitive gymnast has experienced amenorrhea for the past 5 years. Her PCP is suspecting that she
may have premature osteoporosis. Would you expect her OPG levels to be high, normal, or low? Explain why her levels
would be at this level.
Correct Answer
Her OPG levels would be low. Amenorrhea results in lower estrogen levels. Estrogen increases the production of OPG
in turn decreasing osteoclast activity. If estrogen levels are low, OPG levels would also be low resulting in increased
osteoclast activity.
Rationale:
Amenorrhea leads to lower estrogen levels, which in turn results in decreased production of Osteoprotegerin (OPG). With lower OPG
levels, osteoclast activity increases, as OPG normally helps to inhibit osteoclast activity, making it more likely for the 22-year-old
gymnast to experience premature osteoporosis.
Question 3
A patient presents to the ER with severe pain in their right ankle. Blood tests reveal serum uric acid levels of 7.8
mg/dL. They are kept for observation and their 24-hr urine specimen reveals underexcretion of urate. Which phase of
gout are they in? What is the goal of your treatment given the phase they are in?
Correct Answer
This patient is in phase 2 of gout or acute gout arthritis. The goal of treatment is to manage symptoms and terminate
the acute attack primarily through NSAIDS.
Rationale:
The patient is in phase 2 of gout because they are experiencing an acute gout attack, indicated by severe pain in their ankle, and their
24-hr urine specimen reveals underexcretion of urate, a key factor in gout development. The goal of treatment is to manage
symptoms and terminate the acute attack primarily through NSAIDs, as phase 2 is focused on acute management and symptom relief,
rather than addressing the underlying pathophysiology or preventing future attacks.
Trusted by thousands of students and professionals worldwide Page 2 of 9
