,NR566 Week 4 50 Real Exam Questions & Answers
1. In Chronic Kidney Disease (CKD), what are the first-line agents
recommended to reduce proteinuria and slow disease progression?
A. Calcium channel blockers
B. ACE inhibitors or ARBs
C. Loop diuretics
D. Beta-blockers
Answer: B. ACE inhibitors or ARBs
Explanation: According to the provided resource (Page 1, Q1), ACE
inhibitors or ARBs are the first-line agents for reducing proteinuria and
slowing the progression of CKD. These medications help by reducing
intraglomerular pressure, which is a key mechanism in proteinuria and
subsequent renal damage.
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2. Which electrolyte abnormality commonly seen in CKD poses the greatest
risk for causing malignant ventricular arrhythmias?
A. Hypocalcemia
B. Hyperkalemia
C. Hypermagnesemia
D. Hypernatremia
Answer: B. Hyperkalemia
Explanation: The resource explicitly states that hyperkalemia is the
electrolyte abnormality most responsible for malignant ventricular
arrhythmia risk in CKD (Page 1, Q2). Elevated potassium levels disrupt the
heart's electrical conduction system, which can lead to life-threatening
arrhythmias.
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3. Anemia in patients with Chronic Kidney Disease is primarily a complication
resulting from:
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, A. Chronic blood loss in the gastrointestinal tract
B. Reduced production of erythropoietin by the kidneys
C. Iron deficiency from poor dietary intake
D. Shortened lifespan of red blood cells
Answer: B. Reduced production of erythropoietin by the kidneys
Explanation: The kidneys are the primary source of erythropoietin (EPO), a
hormone that stimulates red blood cell production in the bone marrow. As
per the resource (Page 1, Q3), the anemia of CKD is chiefly due to the
failing kidneys' inability to produce sufficient EPO.
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4. Uremic pericarditis, an inflammation of the heart's lining seen in advanced
CKD, is caused by:
A. Viral infection
B. Accumulated nitrogenous wastes (uremic toxins)
C. Autoimmune reaction against cardiac tissue
D. Fluid overload leading to pericardial effusion
Answer: B. Accumulated nitrogenous wastes (uremic toxins)
Explanation: Uremic pericarditis is a direct complication of uremia, the
syndrome associated with the buildup of nitrogenous waste products in the
blood due to kidney failure (Page 1, Q4). These toxins are thought to irritate
the pericardial sac, causing inflammation.
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5. The primary driver of secondary hyperparathyroidism in patients with CKD
is:
A. Hypocalcemia stimulating PTH release
B. Hyperphosphatemia with low calcitriol (active vitamin D) levels
C. Hypermagnesemia inhibiting parathyroid gland function
D. Metabolic acidosis increasing bone resorption
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