HESI Specialty Examination Practice Exam (Modeled After
Official HESI Specialty Exams) Newest 2025 – 2026
Questions From Actual Exams Complete Questions And
Correct Detailed Answers (Verified Answers) |Already
Graded A+||Brand New!!
Content Covered (Most Frequently Tested Topics)
Pharmacology and Medication Administration
Cardiovascular Disorders
Respiratory Disorders
Neurological Conditions
Endocrine Disorders
Renal and Fluid/Electrolyte Balance
Gastrointestinal Disorders
Maternal and Newborn Nursing
Pediatric Nursing
Infection Control and Safety
Mental Health Nursing
Emergency and Critical Care Priorities
Nursing Process and Clinical Judgment
1. A nurse is caring for a patient receiving morphine for postoperative pain. Which
assessment finding requires immediate intervention?
A. Respiratory rate of 10 breaths/min
B. Heart rate of 88 bpm
C. Blood pressure of 124/78 mmHg
D. Temperature of 37.1°C
Answer: 10 breaths/min
Morphine is an opioid that depresses the respiratory center. A respiratory rate below 12
breaths/min suggests opioid-induced respiratory depression and requires immediate
intervention.
2. A patient with heart failure reports sudden weight gain of 2 kg in two days. What is the
most appropriate nursing action?
,A. Increase oral fluid intake
B. Notify the healthcare provider
C. Encourage exercise
D. Discontinue diuretics
Answer: Notify the healthcare provider
Rapid weight gain indicates fluid retention and worsening heart failure. The provider should
be notified for medication adjustment.
3. Which electrolyte imbalance is commonly associated with loop diuretics such as
furosemide?
A. Hypernatremia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Answer: Hypokalemia
Loop diuretics increase urinary potassium excretion, commonly leading to hypokalemia.
4. A patient with diabetic ketoacidosis (DKA) is admitted to the emergency department.
Which treatment is initiated first?
A. Subcutaneous insulin
B. Sodium bicarbonate
C. Intravenous fluids
D. Oral glucose
Answer: Intravenous fluids
Severe dehydration occurs in DKA. Fluid resuscitation is the priority before insulin therapy.
5. A nurse is caring for a patient with suspected stroke. Which symptom requires immediate
emergency evaluation?
A. Mild headache
B. Sudden unilateral weakness
C. Intermittent dizziness
D. Fatigue
Answer: Sudden unilateral weakness
Sudden neurological deficits such as unilateral weakness indicate possible stroke and require
rapid evaluation.
, 6. Which isolation precaution is required for a patient with active tuberculosis?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Standard precautions
Answer: Airborne precautions
Tuberculosis spreads through airborne particles; patients require negative pressure rooms and
N95 masks.
7. A nurse is assessing a patient with hypoglycemia. Which symptom is most expected?
A. Polyuria
B. Diaphoresis
C. Slow pulse
D. Warm dry skin
Answer: Diaphoresis
Low blood glucose activates the sympathetic nervous system causing sweating, tremors, and
tachycardia.
8. A patient receiving heparin therapy develops bleeding gums. Which laboratory test
should the nurse review?
A. INR
B. Platelet count
C. aPTT
D. Hemoglobin
Answer: aPTT
Activated partial thromboplastin time monitors the therapeutic level of heparin.
9. A newborn has a heart rate of 90 bpm immediately after birth. What is the priority
nursing action?
A. Provide warmth
B. Initiate positive pressure ventilation
C. Start chest compressions
D. Give oxygen by mask
Answer: Initiate positive pressure ventilation
Official HESI Specialty Exams) Newest 2025 – 2026
Questions From Actual Exams Complete Questions And
Correct Detailed Answers (Verified Answers) |Already
Graded A+||Brand New!!
Content Covered (Most Frequently Tested Topics)
Pharmacology and Medication Administration
Cardiovascular Disorders
Respiratory Disorders
Neurological Conditions
Endocrine Disorders
Renal and Fluid/Electrolyte Balance
Gastrointestinal Disorders
Maternal and Newborn Nursing
Pediatric Nursing
Infection Control and Safety
Mental Health Nursing
Emergency and Critical Care Priorities
Nursing Process and Clinical Judgment
1. A nurse is caring for a patient receiving morphine for postoperative pain. Which
assessment finding requires immediate intervention?
A. Respiratory rate of 10 breaths/min
B. Heart rate of 88 bpm
C. Blood pressure of 124/78 mmHg
D. Temperature of 37.1°C
Answer: 10 breaths/min
Morphine is an opioid that depresses the respiratory center. A respiratory rate below 12
breaths/min suggests opioid-induced respiratory depression and requires immediate
intervention.
2. A patient with heart failure reports sudden weight gain of 2 kg in two days. What is the
most appropriate nursing action?
,A. Increase oral fluid intake
B. Notify the healthcare provider
C. Encourage exercise
D. Discontinue diuretics
Answer: Notify the healthcare provider
Rapid weight gain indicates fluid retention and worsening heart failure. The provider should
be notified for medication adjustment.
3. Which electrolyte imbalance is commonly associated with loop diuretics such as
furosemide?
A. Hypernatremia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Answer: Hypokalemia
Loop diuretics increase urinary potassium excretion, commonly leading to hypokalemia.
4. A patient with diabetic ketoacidosis (DKA) is admitted to the emergency department.
Which treatment is initiated first?
A. Subcutaneous insulin
B. Sodium bicarbonate
C. Intravenous fluids
D. Oral glucose
Answer: Intravenous fluids
Severe dehydration occurs in DKA. Fluid resuscitation is the priority before insulin therapy.
5. A nurse is caring for a patient with suspected stroke. Which symptom requires immediate
emergency evaluation?
A. Mild headache
B. Sudden unilateral weakness
C. Intermittent dizziness
D. Fatigue
Answer: Sudden unilateral weakness
Sudden neurological deficits such as unilateral weakness indicate possible stroke and require
rapid evaluation.
, 6. Which isolation precaution is required for a patient with active tuberculosis?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Standard precautions
Answer: Airborne precautions
Tuberculosis spreads through airborne particles; patients require negative pressure rooms and
N95 masks.
7. A nurse is assessing a patient with hypoglycemia. Which symptom is most expected?
A. Polyuria
B. Diaphoresis
C. Slow pulse
D. Warm dry skin
Answer: Diaphoresis
Low blood glucose activates the sympathetic nervous system causing sweating, tremors, and
tachycardia.
8. A patient receiving heparin therapy develops bleeding gums. Which laboratory test
should the nurse review?
A. INR
B. Platelet count
C. aPTT
D. Hemoglobin
Answer: aPTT
Activated partial thromboplastin time monitors the therapeutic level of heparin.
9. A newborn has a heart rate of 90 bpm immediately after birth. What is the priority
nursing action?
A. Provide warmth
B. Initiate positive pressure ventilation
C. Start chest compressions
D. Give oxygen by mask
Answer: Initiate positive pressure ventilation
