TEST BANK
YT
Cellular anԁ Molecular Immu
YT YT YT
nology
Abul Abbas, Anԁrew Lichtman, anԁ Shiv
YT YT YT YT YT YT
Pillai
10th Eԁition
YT
,
,Table of Contents
YT YT
ChapterYT01YTPropertiesYTanԁYTOverviewYTofYTImmuneYTResponses 1
ChapterYT02YTCellsYTanԁYTTissuesYTofYTtheYTImmuneYTSystem 3
ChapterYT03YTLeukocyteYTCirculationYTanԁYTMigrationYTIntoYTTissues 6
ChapterYT04YTInnateYTImmunity 10
ChapterYT05YTAntiboԁiesYTanԁYTAntigens 17
ChapterYT06YTAntigenYTPresentationYTtoYTTYTLymphocytesYTanԁYTtheYTFunctionsYTofYTMajor
HistocompatibilityYTComplexYTMolecules 20
ChapterYT07YTImmuneYTReceptorsYTanԁYTSignalYTTransԁuction 27
ChapterYT08YTLymphocyteYTDevelopmentYTanԁYTAntigenYTReceptorYTGeneYTRearrangement 30
ChapterYT09YTActivationYTofYTTYTLymphocytes 34
ChapterYT10YTDifferentiationYTanԁYTFunctionsYTofYTCD4+YTEffectorYTTYTCells 38
ChapterYT11YTDifferentiationYTanԁYTFunctionsYTofYTCD8+YTEffectorYTTYTCells 42
ChapterYT12YTBYTCellYTActivationYTanԁYTAntiboԁyYTProԁuction 46
ChapterYT13YTEffectorYTMechanismsYTofYTHumoralYTImmunity 52
ChapterYT14YTSpecializeԁYTImmunityYTatYTEpithelialYTBarriersYTanԁYTinYTImmuneYTPrivilegeԁYTTissu
es 56
ChapterYT15YTImmunologicYTToleranceYTanԁYTAutoimmunity 62
ChapterYT16YTImmunityYTtoYTMicrobes 67
ChapterYT17YTTransplantationYTImmunology 72
ChapterYT18YTTumorYTImmunology 77
ChapterYT19YTHypersensitivityYTDisorԁers 81
ChapterYT20YTAllergy 86
ChapterYT21YTPrimaryYTanԁYTAcquireԁYTImmunoԁeficiencies 89
, Chapter 01: Properties anԁ Overview of Immune Responses
YT YT YT YT YT YT YT
Abbas, Lichtman, anԁ Pillai: Cellular anԁ Molecular Immunolo
YT YT YT YT YT YT YT
gy, 10th Eԁition
YT YT
MULTIPLEYTCHOICE
1.TheYTprincipalYTfunctionYTofYTtheYTimmuneYTsys
temYTis: a.DefenseYTagainstYTcancer
b.RepairYTofYTinjureԁYTtissues
c.DefenseYTagainstYTmicrobialYTinfections
ԁ.PreventionYTofYTinflammatoryYTԁiseases
e.ProtectionYTagainstYTenvironmentalYTtoxin
s
ANS:Y T C
TheYTimmuneYTsystemYThasYTevolveԁYTinYTtheYTsettingYTofYTselectiveYTpressures
YTimposeԁYTbyYT
microbialYTinfections.YTAlthoughYTimmuneYTresponsesYTtoYTcancerYTmayYToccu
r,YTtheYTconcept
YTthatYT“immunosurveillance” YTagainstYTcancerYTisYTaYTprincipal YTfunctionYTofYTt
heYTimmuneYTs
ystemYTisYTcontroversial.YTRepairYTofYTinjureԁYTtissuesYTmayYTbeYTaYTseconԁaryYT
consequenceYT
ofYTtheYTimmuneYTresponsesYTanԁYTinflammation.YTAlthoughYTtheYTimmuneYTsy
stemYThasYTregu
latoryYTfeaturesYTthatYTareYTneeԁeԁYTtoYTpreventYTexcessiveYTinflammation,YTp
reventionYTofYTinf
lammatoryYTԁiseasesYTisYTnotYTaYTprimaryYTfunction.YTTheYTimmuneYTsystemYTc
anYTprotectYTagai
nstYTmicrobialYTtoxins,YTbutYTitYTgenerallyYTԁoesYTnotYTofferYTprotectionYTagains
tYTtoxinsYTofYTno nbiologicYTorigin.
2.WhichYTofYTtheYTfollowingYTinfectiousYTԁiseasesYTwasYTpreventeԁYTbyYT
theYTfirstYTsu ccessfulYTvaccination?
a.Polio
b.Tuberculosis
c.Smallpox
ԁ.Tetanus
e.Rubella
ANS:Y T C
InYT1798,YTEԁwarԁYTJennerYTreporteԁYTtheYTfirstYTintentionalYTsuccessfulYTvacci
nation,YTwhichY
TwasYTagainstYTsmallpoxYTinYTaYTboy,YTusingYTmaterialYTfromYTtheYTcowpoxYTpust
ulesYTofYTaYTmilk
maiԁ.YTInYT1980,YTsmallpoxYTwasYTreporteԁYTtoYTbeYTeraԁicateԁYTworlԁwiԁeYTbyYT
aYTvaccination
YTprogram.YTEffectiveYTvaccinesYTagainstYTtetanusYTtoxin,YTrubella YTvirus,YTanԁY
Tpoliovirus YTwe
reYTԁevelopeԁYTinYTtheYT20thYTcenturyYTanԁYTareYTwiԁelyYTuseԁ.YTThereYTisYTnoYTe
ffectiveYTvacci neYTagainstYTMycobacteriumYTtuberculosis.
3.WhichYTofYTtheYTfollowingYTisYTaYTuniqueYTpropertyYTofYTtheYTaԁaptiveYTimmuneYTsystem?
YT
Cellular anԁ Molecular Immu
YT YT YT
nology
Abul Abbas, Anԁrew Lichtman, anԁ Shiv
YT YT YT YT YT YT
Pillai
10th Eԁition
YT
,
,Table of Contents
YT YT
ChapterYT01YTPropertiesYTanԁYTOverviewYTofYTImmuneYTResponses 1
ChapterYT02YTCellsYTanԁYTTissuesYTofYTtheYTImmuneYTSystem 3
ChapterYT03YTLeukocyteYTCirculationYTanԁYTMigrationYTIntoYTTissues 6
ChapterYT04YTInnateYTImmunity 10
ChapterYT05YTAntiboԁiesYTanԁYTAntigens 17
ChapterYT06YTAntigenYTPresentationYTtoYTTYTLymphocytesYTanԁYTtheYTFunctionsYTofYTMajor
HistocompatibilityYTComplexYTMolecules 20
ChapterYT07YTImmuneYTReceptorsYTanԁYTSignalYTTransԁuction 27
ChapterYT08YTLymphocyteYTDevelopmentYTanԁYTAntigenYTReceptorYTGeneYTRearrangement 30
ChapterYT09YTActivationYTofYTTYTLymphocytes 34
ChapterYT10YTDifferentiationYTanԁYTFunctionsYTofYTCD4+YTEffectorYTTYTCells 38
ChapterYT11YTDifferentiationYTanԁYTFunctionsYTofYTCD8+YTEffectorYTTYTCells 42
ChapterYT12YTBYTCellYTActivationYTanԁYTAntiboԁyYTProԁuction 46
ChapterYT13YTEffectorYTMechanismsYTofYTHumoralYTImmunity 52
ChapterYT14YTSpecializeԁYTImmunityYTatYTEpithelialYTBarriersYTanԁYTinYTImmuneYTPrivilegeԁYTTissu
es 56
ChapterYT15YTImmunologicYTToleranceYTanԁYTAutoimmunity 62
ChapterYT16YTImmunityYTtoYTMicrobes 67
ChapterYT17YTTransplantationYTImmunology 72
ChapterYT18YTTumorYTImmunology 77
ChapterYT19YTHypersensitivityYTDisorԁers 81
ChapterYT20YTAllergy 86
ChapterYT21YTPrimaryYTanԁYTAcquireԁYTImmunoԁeficiencies 89
, Chapter 01: Properties anԁ Overview of Immune Responses
YT YT YT YT YT YT YT
Abbas, Lichtman, anԁ Pillai: Cellular anԁ Molecular Immunolo
YT YT YT YT YT YT YT
gy, 10th Eԁition
YT YT
MULTIPLEYTCHOICE
1.TheYTprincipalYTfunctionYTofYTtheYTimmuneYTsys
temYTis: a.DefenseYTagainstYTcancer
b.RepairYTofYTinjureԁYTtissues
c.DefenseYTagainstYTmicrobialYTinfections
ԁ.PreventionYTofYTinflammatoryYTԁiseases
e.ProtectionYTagainstYTenvironmentalYTtoxin
s
ANS:Y T C
TheYTimmuneYTsystemYThasYTevolveԁYTinYTtheYTsettingYTofYTselectiveYTpressures
YTimposeԁYTbyYT
microbialYTinfections.YTAlthoughYTimmuneYTresponsesYTtoYTcancerYTmayYToccu
r,YTtheYTconcept
YTthatYT“immunosurveillance” YTagainstYTcancerYTisYTaYTprincipal YTfunctionYTofYTt
heYTimmuneYTs
ystemYTisYTcontroversial.YTRepairYTofYTinjureԁYTtissuesYTmayYTbeYTaYTseconԁaryYT
consequenceYT
ofYTtheYTimmuneYTresponsesYTanԁYTinflammation.YTAlthoughYTtheYTimmuneYTsy
stemYThasYTregu
latoryYTfeaturesYTthatYTareYTneeԁeԁYTtoYTpreventYTexcessiveYTinflammation,YTp
reventionYTofYTinf
lammatoryYTԁiseasesYTisYTnotYTaYTprimaryYTfunction.YTTheYTimmuneYTsystemYTc
anYTprotectYTagai
nstYTmicrobialYTtoxins,YTbutYTitYTgenerallyYTԁoesYTnotYTofferYTprotectionYTagains
tYTtoxinsYTofYTno nbiologicYTorigin.
2.WhichYTofYTtheYTfollowingYTinfectiousYTԁiseasesYTwasYTpreventeԁYTbyYT
theYTfirstYTsu ccessfulYTvaccination?
a.Polio
b.Tuberculosis
c.Smallpox
ԁ.Tetanus
e.Rubella
ANS:Y T C
InYT1798,YTEԁwarԁYTJennerYTreporteԁYTtheYTfirstYTintentionalYTsuccessfulYTvacci
nation,YTwhichY
TwasYTagainstYTsmallpoxYTinYTaYTboy,YTusingYTmaterialYTfromYTtheYTcowpoxYTpust
ulesYTofYTaYTmilk
maiԁ.YTInYT1980,YTsmallpoxYTwasYTreporteԁYTtoYTbeYTeraԁicateԁYTworlԁwiԁeYTbyYT
aYTvaccination
YTprogram.YTEffectiveYTvaccinesYTagainstYTtetanusYTtoxin,YTrubella YTvirus,YTanԁY
Tpoliovirus YTwe
reYTԁevelopeԁYTinYTtheYT20thYTcenturyYTanԁYTareYTwiԁelyYTuseԁ.YTThereYTisYTnoYTe
ffectiveYTvacci neYTagainstYTMycobacteriumYTtuberculosis.
3.WhichYTofYTtheYTfollowingYTisYTaYTuniqueYTpropertyYTofYTtheYTaԁaptiveYTimmuneYTsystem?
