A4M Written Exam 2026 Exam
Questions and Verified Answers
| Already Graded A+
Mechanism of action of curcumin Supplement whose mechanism includes
decreasing tau phosphorylation and reducing COX-2 expression. -
🧠ANSWER ✔✔Curcumin is an inhibitor of phosphorylase kinase. It
decreases tau phosphorylation; reduces COX-2 expression; inhibits NF-kB.
Stimulates neutrophils and macrophages to kill microorganism. Nontoxic
and does not cause microbial resistance. Useful for treatment of
intracellular organisms. - 🧠ANSWER ✔✔Olive leaf extract
,Rate of secretion of PSA from prostate / day? - 🧠ANSWER ✔✔0.07 ng / mL
Mineral responsible for increasing renal intra-glomerular pressure and
decreasing arterial compliance - 🧠ANSWER ✔✔Sodium
How much does potassium decrease BP? - 🧠ANSWER ✔✔Supplementing
potassium 60-120 mEG day may decrease SBP / DBP by 4/2.5 mm HG
Actions of Magnesium on BP: are - 🧠ANSWER ✔✔- Acts as a calcium
channel blocker
- Regulates insulin sensitivity
- Regulates pH
- Increases arterial compliance via endothelial vasodilatation
T or F: omega-6 fatty acids decrease blood pressure - 🧠ANSWER ✔✔False
(although may indirectly affect BP through effects on saturated fatty acids)
Recommended intake of calcium to reduce HTN - 🧠ANSWER ✔✔> 800 mg
/ day may reduce incidence of HTN
T or F: soy protein decreases blood pressure and increases arterial
compliance - 🧠ANSWER ✔✔True; recommended in fermented form; 30-40
gm / day for hypertensive individuals
,T or F: omega-9 fatty acids found in olive oil have beneficial effects on both
blood pressure and cholesterol - 🧠ANSWER ✔✔True
Effects of garlic on HTN - 🧠ANSWER ✔✔garlic acts as a natural ACE-I,
CCB and increases arterial compliance via increase of NO production
T or F: The gamma isomer of Vitamin E is more potent than the alpha
isomer in lipid lowering effects - 🧠ANSWER ✔✔True
Most potent B vitamin; lowers blood pressure via multiple mechanisms -
🧠ANSWER ✔✔Vitamin B6. Increases bioavailability of coA and decreases
cholesterol synthesis. Also reduces oxLDL. Increases HDL, reduces LDL
and triglycerides.
T or F: There is strong evidence for Guggul in treatment of cholesterol -
🧠ANSWER ✔✔False
T or F: Niacin is the most effective currently known agent for increasing
HDL - 🧠ANSWER ✔✔True
Which infectious agents have been linked to development of MS plaques in
brain? - 🧠ANSWER ✔✔Mycoplasma pneumoniae and EBV
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2026. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
, T or F: 20% of MS patients have been shown to have gluten sensitivity -
🧠ANSWER ✔✔True
What pharmaceutical / nutriceutical agents have been shown to be helpful
in treatment of MS? - 🧠ANSWER ✔✔Alpha lipoic acid; minocycline;
doxycycline; memantine; NAC; Vitamin B12; phosphatidyl serine;
Coenzyme Q10; HRT with estrogen / estriol; hyperbaric oxygen therapy
What are the risk factors for sub-arachnoid hemorrhage (rupture of cerebral
aneurysm)? - 🧠ANSWER ✔✔Hypertension; smoking; oral contraceptive
usage; usage of stimulants
What is the mechanism of action of migraine headache? - 🧠ANSWER
✔✔Extreme cerebral vasoconstriction followed by vaso-dilatation
Which neuro-transmitter deficiencies have been implicated in the
development of migraine headaches? - 🧠ANSWER ✔✔GABA and
serotonin
T or F: thymectomy is recommended for treatment of myasthenia gravis -
🧠ANSWER ✔✔False; current evidence does not support thymus removal
due to risks of surgery and lack of evidence; however, 70% of patients with
Questions and Verified Answers
| Already Graded A+
Mechanism of action of curcumin Supplement whose mechanism includes
decreasing tau phosphorylation and reducing COX-2 expression. -
🧠ANSWER ✔✔Curcumin is an inhibitor of phosphorylase kinase. It
decreases tau phosphorylation; reduces COX-2 expression; inhibits NF-kB.
Stimulates neutrophils and macrophages to kill microorganism. Nontoxic
and does not cause microbial resistance. Useful for treatment of
intracellular organisms. - 🧠ANSWER ✔✔Olive leaf extract
,Rate of secretion of PSA from prostate / day? - 🧠ANSWER ✔✔0.07 ng / mL
Mineral responsible for increasing renal intra-glomerular pressure and
decreasing arterial compliance - 🧠ANSWER ✔✔Sodium
How much does potassium decrease BP? - 🧠ANSWER ✔✔Supplementing
potassium 60-120 mEG day may decrease SBP / DBP by 4/2.5 mm HG
Actions of Magnesium on BP: are - 🧠ANSWER ✔✔- Acts as a calcium
channel blocker
- Regulates insulin sensitivity
- Regulates pH
- Increases arterial compliance via endothelial vasodilatation
T or F: omega-6 fatty acids decrease blood pressure - 🧠ANSWER ✔✔False
(although may indirectly affect BP through effects on saturated fatty acids)
Recommended intake of calcium to reduce HTN - 🧠ANSWER ✔✔> 800 mg
/ day may reduce incidence of HTN
T or F: soy protein decreases blood pressure and increases arterial
compliance - 🧠ANSWER ✔✔True; recommended in fermented form; 30-40
gm / day for hypertensive individuals
,T or F: omega-9 fatty acids found in olive oil have beneficial effects on both
blood pressure and cholesterol - 🧠ANSWER ✔✔True
Effects of garlic on HTN - 🧠ANSWER ✔✔garlic acts as a natural ACE-I,
CCB and increases arterial compliance via increase of NO production
T or F: The gamma isomer of Vitamin E is more potent than the alpha
isomer in lipid lowering effects - 🧠ANSWER ✔✔True
Most potent B vitamin; lowers blood pressure via multiple mechanisms -
🧠ANSWER ✔✔Vitamin B6. Increases bioavailability of coA and decreases
cholesterol synthesis. Also reduces oxLDL. Increases HDL, reduces LDL
and triglycerides.
T or F: There is strong evidence for Guggul in treatment of cholesterol -
🧠ANSWER ✔✔False
T or F: Niacin is the most effective currently known agent for increasing
HDL - 🧠ANSWER ✔✔True
Which infectious agents have been linked to development of MS plaques in
brain? - 🧠ANSWER ✔✔Mycoplasma pneumoniae and EBV
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2026. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
, T or F: 20% of MS patients have been shown to have gluten sensitivity -
🧠ANSWER ✔✔True
What pharmaceutical / nutriceutical agents have been shown to be helpful
in treatment of MS? - 🧠ANSWER ✔✔Alpha lipoic acid; minocycline;
doxycycline; memantine; NAC; Vitamin B12; phosphatidyl serine;
Coenzyme Q10; HRT with estrogen / estriol; hyperbaric oxygen therapy
What are the risk factors for sub-arachnoid hemorrhage (rupture of cerebral
aneurysm)? - 🧠ANSWER ✔✔Hypertension; smoking; oral contraceptive
usage; usage of stimulants
What is the mechanism of action of migraine headache? - 🧠ANSWER
✔✔Extreme cerebral vasoconstriction followed by vaso-dilatation
Which neuro-transmitter deficiencies have been implicated in the
development of migraine headaches? - 🧠ANSWER ✔✔GABA and
serotonin
T or F: thymectomy is recommended for treatment of myasthenia gravis -
🧠ANSWER ✔✔False; current evidence does not support thymus removal
due to risks of surgery and lack of evidence; however, 70% of patients with
