UPDATED ACTUAL Questions and
CORRECT Answers
What causes cystic fibrosis? - CORRECT ANSWER - a mutation in the gene that codes for the
CFTR protein.
What are clinical manifestations of Cystic Fibrosisi? - CORRECT ANSWER - 1. thick and
tenacious sputum that is colonized with bacteria (caused by the infection leading to inflammation)
How does cystic fibrosis affect the pancreas? - CORRECT ANSWER - Causes malabsorption of
protein, fat, and fat-soluble vitamins
What does the medication Pancrelipase do ? - CORRECT ANSWER - helps to metabolism fat
When would pancrelipase be given? - CORRECT ANSWER - With all snacks and meals
What are the most important medical managements of Cystic Fibrosis? - CORRECT ANSWER -
airway clearance and antibiotics (Cystic fibrosis requires both acute and chronic management)
What are the laboratory and diagnostic test for Cystic Fibrosis? - CORRECT ANSWER - 1. Sweat
chloride test greater than 50 = suspicious
greater than 60= diagnostic
2. Pulse oximetry- sat decreased
3. Chest x-ray- shows hyperinflation, bronchial wall thickening, atelectasis, or infiltration
4. Pulmonary Function Test- decreased forced vital capacity and forced expiratory volume, with increase
in residual volume
What is one of the first line antituberculosis medications ? - CORRECT ANSWER - Isoniazid
(INH)
-interferes with b6 absorption so it needs to be supplement
, -causes peripheral neuropathy (report any numbness, tingling, ataxia)
-Can be hepatoxic (avoid alcohol, monitor jaundice, dark urine, fatigue, elevated LFTs)
- avoid tyramine and histamine (will cause headache, flushing, hypotension, lightheadedness, palpitations
and diaphoresis)
Another one of the first line antituberculosis medications? - CORRECT ANSWER - Rifampin
-increases metabolism of oral contraceptives
-can cause body fluids to turn a reddish orange (teach client to wear glasses instead of contacts because
they will be destroyed)
- Monitor LFTs (AST & ALT)
-Monitor jaundice (liver toxicity )
Tuberculosis (TB) - CORRECT ANSWER - an infectious disease that usually attacks the lungs
(can also attach the meninges, kidneys, bones and lymph nodes) transmitted by coughing, sneezing,
talking, singing, and laughing
2 types: Latent (not contagious) and Active TB (contagious)
**transmitted by airborne/droplet transmission **
What are risk factors for TB? - CORRECT ANSWER - - close contact with an infected person
- immigration from a country with a high prevalence of TB
-institutionalization
-crowed or substandard housing
-being a healthcare working performing high risk activities
-immunocompromised status (those with HIV, cancer, transplanted organs, any person without adequate
health care, person who engage in substance abuse, homeless, impoverished)
S/S of TB - CORRECT ANSWER - -low grade fever
- cough
-night sweats