CD34+ cells are correct answers Stem cell marker
CD3+ cells are correct answers T cell marker (collected for CAR-T)
CD19+ cells correct answers B cell marker (on cancer)
Which disease will you complete a CAR-T infusion after the first relapse post-auto? correct
answers DLBCL
Neurotoxicity ICE toxicity correct answers Grade 1 = 7-9
Grade 2 = 3-6
Grade 3 = 0-2
Grade 4 = 0
CRS grade 1 correct answers >38C
No supplemental O2
No BP support
CRS grade 2 correct answers >38C
Supplemental oxygen (okay for floor)
No BP support
CRS grade 3 correct answers >38C
High flow, non-rebreather, face masks, etc
Vasopressors needed
, CRS grade 4 correct answers >38C
CPAP, BiPAP, ventilation
Multiple pressors
First treatment of CRS correct answers Treatment s/sx (Tylenol, fluids) & toci
First line treatment of neurotox correct answers Steroids
What vaccine is given @24months post transplant? correct answers MMR (live vaccine) - if
being treated for chronic GVHD, cannot give as on immunosuppressant
What vaccine is given 4-6months post transplant? correct answers Pneumococcal (PCV), tetanus,
pertussis
Inactive flu!
Survivorship in pediatrics correct answers -Endocrine & gonadal assessment
-annual growth factors
-cognitive development
-ovarian function (RF's: busulfan & TBI)
PJP symptoms correct answers fever, exertional dyspnea, nonproductive cough, weight loss,
sweats, LDH rises
PJP prophylaxis correct answers trimethoprim/sulfamethoxazole
Dapsone also given - can cause low O2 levels