MH701 exam 2 with accurate detailed solutions

2



MH701 exam 2 with accurate detailed solutions || || || || || ||




Parkinsonism signs/symptoms ||




*Resting Tremors: Pin Rolling || || ||




*Rhythmic Oscillatory Movements || ||




*Gait: Posture Stooped, Steps Short and Often Shuffling
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If develops EPS give
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Benztropine or Trihexyphenidyl or Diphenhydramine || || || ||




-High-potency: haloperidol, fluphenazine || ||




-Mid-potency: perphenazine, loxapine || ||




-Low-potency: chlorpromazine ||




-Commonly used first-generation antipsychotics - Haloperidol (Haldol), Fluphenazine
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(Prolixin), Thioridazine (Mellaril), Trifluoperazine (Stelazine)
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-Low dose, high potency Haldol IM 2 - 5 mg have been found to be safe and effective in
|| || || || || || || || || || || || || || || || || || ||




managing agitated psychiatric patients. Subsequent doses may be needed within 1 hour
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depending on responses || ||




How does FGAs differ in potency
|| || || || ||




What are the Atypicals for Bipolar disorder
|| || || || || ||




olanzapine(Zyprexa), quetiapine (Seroquel), risperidone(Risperdal)(Risperdal), || || || ||




aripiprazole(Abilify), and ziprasidone (Geodon) || || ||




What is lithium used for?
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acute mania and maintenance in Bipolar
|| || || || ||




Valproate (Depakote) is used for || || || ||




acute and mixed, off-label maintenance in Bipolar
|| || || || || ||




Lamotrigine (Lamictal) is FDA approved || || || ||




for maintenance in Bipolar, off-label adjunct and second line for bipolar mania, bipolar
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depression

Carbamazepine (Tegretol) is used for || || || ||

,2


Off label for bipolar depression, maintenance
|| || || || ||




*Oxcarbazepine (Trileptal) - NOT established for || || || || ||




tx of mania in Bipolar
|| || || ||




Oxcarbazepine (Trileptal) may aid in || || || ||




tx of aggression and impulsivity in Bipolar
|| || || || || ||




Is gabapentin (Neurontin) and topiramate (Topamax) although established for tx Bipolar
|| || || || || || || || || ||




No

Lithium - risk of suicide || || || ||




decreased 13-fold with long-term maintenance therapy || || || || ||




Depakote is preferred for || || ||




rapid cycling disorders
|| ||




Hypomanic episodes and mild depressive episodes generally managed with
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single mood stabilizer || ||




Acute mania and severe depressive may require
|| || || || || ||




2-3 different medications
|| ||




With bipolar Avoid
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antidepressants in depressives may precipitate mania or rapid cycling || || || || || || || ||




what are the neurotransmitters involved in the pathology of mood disorders?
|| || || || || || || || || ||




Norepinephrine and serotonin are the two neurotransmitters most implicated in the || || || || || || || || || || ||




pathophysiology of mood disorders. || || ||




what 2 classes of medications are used to treat early-onset bipolar disorder?
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Atypical antipsychotics and mood-stabilizing agents are the most well-studied agents that
|| || || || || || || || || || ||




provide efficacy in the treatment || || || ||




What are specific examples of common medications used to treat early onset bipolar
|| || || || || || || || || || || || ||




disorder from each class of medications? || || || || ||




atypical antipsychotics include: olanzapine(Zyprexa), Quetiapine (Seroquel),
|| || || || || ||




risperidone(Risperdal), aripiprazole (Abilify), and ziprasidone (Geodon). || || || || ||

, 2


Between quetiapine (Seroquel) and valproate (Depakote) which one is superior
|| || || || || || || || || ||




inefficacious and speed of its effect in bipolar youth || || || || || || || ||




quetiapine (Seroquel) ||




Between risperidone(Risperdal) and Divalproex (Depakote). which had a more rapid
|| || || || || || || || || ||




improvement and a greater final reduction in manic symptoms || || || || || || || ||




risperidone(Risperdal)

Where Gabapentin found to be most useful?
|| || || || || ||




Epilepsy, pain management || ||




How has Some bipolar patients have benefited when Gabapentin
|| || || || || || || ||




as adjunctively with mood stabilizers
|| || || ||




Gabapentin is used as a _____________ because of its sedating effects
|| || || || || || || || || ||




hypnotic agent ||




-Where Topiramate (Topamax) found to of most benefit for various psychiatric disorders or
|| || || || || || || || || || || || ||




for treatment of what symptoms?
|| || || ||




epilepsy, migraine prevention, obesity treatment, binge eating, bulimia, and alcohol
|| || || || || || || || || ||




dependence

How much does Topiramate (Topamax) benefit in the treatment of psychotic disorders
|| || || || || || || || || || ||




little or no benefit || || ||




Is Topiramate effective as monotherapy in acute mania
|| || || || || || ||




Nope

Topiramate with Bupropion effective in bipolar depression. || || || || || ||




A little
||




Calcium channel blockers-what are their uses in practice?
|| || || || || || ||




as maintenance therapy in persons with bipolar illness
|| || || || || || ||




What are all the contraindications/drug interactions for use of Carbamazepine (Tegretol)
|| || || || || || || || || || ||




and Oxcarbazepine (Trileptal) for your patient?
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