Actual Complete Exam |Already Graded A+
____ is the most appropriate answer because there are no drug-drug interactions or
contraindications / cautions in HIV ✔Correct Answer-Bictegravir
n patients with persistent neutropenic fever despite anti-pseudomonal coverage, what should
be considered? ✔Correct Answer-empiric antifungal therapy should be considered after 4 - 10
days
electrocautery ✔Correct Answer-Which of the following therapies is most likely to result in a
resolution rate which approaches 100% in patients w/ external anogenital warts.?
preferred therapy for CMV retinitis? ✔Correct Answer-Ganciclovir intravitreal injections plus
valganciclovir oral
bacterial vaginosis recommended treatment ✔Correct Answer-clindamycin or metronidazole
(i.e. Clindamycin 300 mg orally twice daily for 7 days)
recommended treatment regimen for pelvic inflammatory disease ✔Correct Answer-
Ceftriaxone 250 mg intramuscularly x 1 dose plus doxycycline 100 mg orally twice daily for 14
days
vulvovaginal candidiasis teeatment ✔Correct Answer-Clindamycin cream 2%, 5 g
intravaginally at bedtime for 7 days
MedWatch ✔Correct Answer-preferred route for healthcare professionals and patients to
report suspected adverse events to the FDA
FDA Form 3500A ✔Correct Answer-mechanism for reporting suspected adverse events, but is
reserved for use by user-facilities, importers, distributors, and manufacturers
-reporting errors related to vaccines ✔Correct Answer-ISMP VERP and VAERS
viral rhinosinusitis sx duration ✔Correct Answer--peak at 3 days and may persist longer than
14 days but usually decreases in severity by 10 days
-watchful waiting is recommended to avoid overuse of antibiotics as episodes are often self-
limited
, Malignant external otitis treatment ✔Correct Answer-- predominantly caused by
Pseudomonas aeruginosa
-antipseudomonal antimicrobials are considered the mainstay of therapy.
Fidaxomicin ✔Correct Answer--associated with decreased recurrence of Clostridioides difficile
likely owing to its narrow spectrum and minimal effect on normal colonic flora
duration of initial therapy for CDI? ✔Correct Answer-10 days with oral vancomycin or
fidaxomicin
MRSA PCR ✔Correct Answer--well-recognized tool for antimicrobial de-escalation as part of
stewardship initiatives given the high negative predictive value
MRSA nasal culture ✔Correct Answer--used for surveillance and is not employed as a
stewardship tool
Procalcitonin ✔Correct Answer--useful in differentiating between viral and bacterial etiologies
-chronic kidney disease may cause an artificially high level leading to questionable
interpretation and potential continuation of inappropriate antimicrobials
Asymptomatic candiduria ✔Correct Answer--common among hospitalized patients with an
indwelling urinary catheter and treatment is nt is not warranted
elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (EVG/c/FTC/TAF) ✔Correct
Answer-Elvitegravir is only available in single-tablet regimen form; either as EVG/c/FTC/TAF or
EVG/c/FTC/TDF. Therefore, it is not possible to stock the single agents and "break up" the
patient's regimen
Waterfall plot ✔Correct Answer--Waterfall plot is ideal to represent secondary objectives.
BRAF Mutation ✔Correct Answer-BRAF mutation confers resistance to EGFR inhibitors; Anti-
EGFR therapies should be avoided in KRAS WT and BRAF mutant mCRC unless given in
combination with BRAF inhibitor
Palbociclib ✔Correct Answer--FDA approval for male breast cancer in combination with an
aromatase inhibitor or fulvestrant for men with hormone receptor-positive (HR+), human
epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer
Atezolizumab combined with nab-paclitaxel ✔Correct Answer--in breast CA is based on the
PD-L1 expression on tumor-infiltrating immune cells
Olaparib ✔Correct Answer--Breast cancer
-metastatic,
-HER2-negative -germline BRCA-mutated (gBRCAm)