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A 56-year-old female patient with type 2 diabetes mellitus is not adequately controlled on the
current metformin dose of 1,000 mg twice daily. The patient's A1c was checked one week ago,
and it was 7.9%. The patient's body mass index is 32 kg/m2, and she has no other significant
medical history.
Which medication should be added to the patient's regimen?
A) Glipizide
B) Insulin glargine
C) Liraglutide
D) Sitagliptin ✔Correct Answer-C
Which patient is a candidate for the 12-dose directly observed therapy regimen of isoniazid /
rifapentine for latent tuberculosis infection?
A) 6-month-old infant
B) 26-year-old man who is HIV-positive and taking antiretrovirals
C) 36-year-old pregnant woman
D) 40-year-old man with hypertension ✔Correct Answer-D
Which guidance should be given to a patient receiving amphetamine / dextroamphetamine
mixed salts extended release 20 mg orally once daily for a recent diagnosis of attention deficit
hyperactivity disorder?
A) This medication might cause drowsiness. Use caution when driving or operating heavy
machinery.
B) This medication might cause suicidal ideation. Seek help if you have thoughts of hurting
yourself.
C) This medication might cause weight gain. A diet low in fat and carbohydrates is highly
recommended.
D) This medication might increase the likelihood of developing tics. ✔Correct Answer-B
A 48-year-old female patient receives left-ventricular-assist device placement in the
cardiothoracic surgery ICU. Two days later, the patient remains intubated and mechanically
ventilated and continues to require hemodynamic support with several vasopressors.
The following laboratory values are observed:
SCr 1.9 mg/dL (baseline 0.7 mg/dL)
,WBC 13,600 cells/mm3
Urine output (past 24 hours) 20 mL
Plt 248,000 cells/mm3
AST 37 units/L
ALT 24 units/L
Total bilirubin 1 mg/dL
Which medication should be utilized for pain control in this patient?
A) Acetaminophen 1,000 mg intravenously every 4 hours
B) Fentanyl 25 mcg/hr continuous intravenous infusion
C) Meperidine 50 mg intravenously every 4 hours
D) Morphine 2 mg/hr continuous intravenous infusion ✔Correct Answer-B
A patient with symptomatic lower extremity peripheral artery disease and chronic heart failure
(Class II, ejection fraction 40%) presents to a clinic with increased shortness of breath while
walking on flat surfaces.
The patient's medications include the following:
Aspirin 81 mg dailyFurosemide 40 mg once dailyPotassium chloride 10 mEq once
dailyMetoprolol succinate 100 mg once dailyLisinopril 20 mg once dailyCilostazol 100 mg twice
daily
Which change should be made in the patient's medication regimen?
A) Add spironolactone 25 mg once daily.
B) Increase aspirin to 325 mg once daily.
C) Increase furosemide to 60 mg once daily.
D) Discontinue cilostazol 100 mg twice daily. ✔Correct Answer-D
A 55-year-old woman calls a clinic and asks if she should stop her hormone replacement therapy
after hearing a program on the news. She is currently taking conjugated equine estrogen 0.625
mg orally daily, medroxyprogesterone 5 mg orally daily, and calcium 500 mg orally twice daily.
Which is an accurate statement regarding this patient's hormone replacement therapy is
correct?
A) It decreases the risk of stroke.
B) It decreases the risk of non-vertebral fracture.
C) It decreases the incidence of cardiovascular disease.
D) It increases the risk of colon cancer. ✔Correct Answer-B
Which is an accurate statement regarding the use of the HPV vaccine?
A) Need for the vaccination must be established beforehand by an HPV or Pap test.
B) The Centers for Disease Control and Prevention recommends the HPV vaccine for girls and
women 9 to 26 years of age.
,C) The HPV vaccine has no demonstrated benefit in girls and women who already have acquired
at least one of the HPV types covered by the vaccine.
D) The HPV vaccine protects against all causes of cervical cancer and genital warts. ✔Correct
Answer-B
A patient received the first dose of the measles, mumps, and rubella (MMR) vaccine 7 days ago
and presents to a clinic with numerous bruises and small red spots on the lower legs. The
patient is diagnosed with thrombocytopenia purpura, which is suspected to be vaccine-induced.
Where should the pharmacotherapy specialist report this adverse effect?
A) CDC/FDA Vaccine Adverse Event Reporting System
B) FDA Adverse Event Reporting System
C) FDA MedWatch
D) ISMP National Vaccine Errors Reporting Program ✔Correct Answer-A
While reviewing the patient's home medications, a pharmacist discovers that a patient has been
taking St. John's wort in addition to prescribed sertraline without consultation with a primary
care provider. The pharmacist educates the patient on potential drug interactions between St.
John's wort and sertraline, and then recommends that the patient take sertraline only.
How should the pharmacotherapy specialist document the interaction with this patient?
A) Communicate the interaction to the patient's prescriber, and request for the prescriber to
document it in the patient's medical record.
B) Enter a note in the patient's medical record describing the interaction and the
recommendation.
C) Place a patient-signed statement verifying the interaction in the patient's medical record.
D) Send a note to the patient's outpatient pharmacy regarding the duplicate therapy.
✔Correct Answer-B
Which intervention is recommended for an 82-year-old patient with documented pneumococcal
pneumonia and gram-positive diplococci who is unresponsive to 3 days of ceftriaxone?
A) Increase the dose of ceftriaxone.
B) Initiate ampicillin / sulbactam.
C) Initiate cefazolin.
D) Initiate vancomycin therapy. ✔Correct Answer-D
A 54-year-old patient with type 2 diabetes mellitus is taking pravastatin 40 mg daily for coronary
artery disease after having a myocardial infarction 10 months ago.
The following laboratory values were observed:
Total cholesterol 265 mg/dL
HDL cholesterol 30 mg/dL
LDL cholesterol1 43 mg/dL
Triglycerides370 mg/dL
, A1c7.1%
Which intervention is recommended?
A) Add niacin.
B) Change from pravastatin to atorvastatin.
C) Change from pravastatin to gemfibrozil.
D) Increase pravastatin. ✔Correct Answer-B
Which of the following NSAIDs would have the highest GI risk?
A) Naproxen
B) Celecoxib
C) Nabumetone
D) Indomethacin ✔Correct Answer-D
Colchicine concentrations would be increased by inhibition of which enzyme?
A) 1A2
B) 2D6
C) 3A4
D) 2C19 ✔Correct Answer-C
Which of the following is false with regards to gout?
A) Patients with gout are at risk for kidney stones as well
B) Patients who eat a lot of seafood may increase the risk for gout
C) Allopurinol is one of the drugs of choice for an acute gout flare
D) Systemic calcineurin inhibitors can raise uric acid levels ✔Correct Answer-C
Which gout medication would be problematic in a patient with uncontrolled diarrhea-
predominant IBS?
A) Allopurinol
B) Colchicine
C) Probenecid
D) Febuxostat ✔Correct Answer-B
There are numerous factors that can increase the risk of gout attacks, which one of these is truly
a risk factor?
A) Alcohol use
B) Cigarette smoking
C) Female